EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Putative phthiocerol dimycocerosate transporter LppX (Lipoprotein LppX)lppX Rv2945c MTCY24G1.04P9WK651
Putative pilus biogenesis operon proteinMXAN_0362Q1DFD71
Putative pilus biogenesis protein PilJ/methyl accepting chemotaxis proteinpilJ Smlt3671B2FR341
Putative PilW protein (Type 4 fimbrial biogenesis protein PilW)pilW Smlt1623B2FJB51
Putative pit accessory proteinSmlt1705B2FK781
Putative poly-hydroxy-butyrate synthesis proteinSmlt3326B2FN331
Putative polymerase/proteinaseyajG S0385 SF0378 AJR25_006310 AJR27_019305A0A0H2VTD91
Putative polymerase/proteinaseyajG ECs0488 Z0537Q8XE621
Putative polysaccharide biosynthesis proteinFSU_1440D9SAA01
Putative polysaccharide deacetylaseCD630_15220Q18C421
Putative polysaccharide deacetylaseCD630_27190Q183F41
Putative polysaccharide deacetylase family proteinVSAK1_24960A6CZ481
Putative polysaccharide-degrading enzymeMXAN_6236Q1CZ081
Putative pore-forming peptideSPy_0800Q9A0F31
Putative porinKPN_04773A6THT51
Putative PorinPP_4465Q88EJ71
Putative porin DACIN5021_0233L9MEG51
Putative positive transcriptional regulatormutR SPy_0496Q9A1321
Putative pre-16S rRNA nuclease (EC 3.1.-.-)spr0176Q8DRE21
Putative pre-16S rRNA nuclease (EC 3.1.-.-)SPy_2113 M5005_Spy1796Q99XP41
Putative primosome component (Helicase loader)dnaI SPy_0340Q9A1D11
Putative pristinamycin I synthase 3MXAN_1023Q1DDI91
Putative processin peptidase (EC 3.4.24.-)PP_5112Q88CR81
Putative PROCESSING PROTEASEjhp_0602Q9ZLH71
Putative prolyl aminopeptidaseVSAK1_01422A6D2H01
Putative proteaseVS_2565B7VK361
Putative proteaseVSAK1_14177A6D7291
Putative proteaseSPy_0590Q9A0W01
Putative proteaseSPy_0591Q9A0V91
Putative PTS system enzyme IISPy_2097Q99XQ41
Putative PTS system, enzyme IIB componentSPy_1710Q99YG91
Putative PTS system, lactose-specific component IIAlacF SPy_1918Q99Y161
Putative PTS system, lactose-specific component IIBC (EC 2.7.1.69)lacE SPy_1917Q99Y171
Putative PTS system, N-acetylglucosamine-specific IIA componentCPC_0098B1BFR71
Putative PTS transport proteinmanX YPO0834Q7CGX31
Putative pullulanaseVSAK1_23704A6CWE71
Putative pullulanasepulA SPy_1972Q99XX81
Putative purine operon repressorpurR SPy_0268Q9A1H41
Putative PydP transporter, NCS1 nucleoside transporter familypydP PP_4035Q88FQ21
Putative pyridine nucleotide-disulphide oxidoreductaseCj0559Q0PAV71
Putative pyruvate carboxylase B subunit (EC 6.4.1.1)pycB Cj0933cQ0P9W61
Putative pyruvate carboxylase, B subunitFSU_1289C9RNK81
Putative pyruvate formate-lyasepfl SPy_1849Q99Y651
Putative pyruvate formate-lyase 2 (EC 2.3.1.54)pflD SPy_2049Q99XT31
Putative pyruvate formate-lyase activating enzymeSPy_2055Q99XS71
Putative reductase / dehydrogenaseSPy_1693Q99YI11
Putative regulator AbrB (AidB regulator)abrB ybgN b0715 JW5097 ECK0704P757471
Putative regulator of flagellationycfJ PP_0837Q88PL31
Putative regulatory proteinCj1507cQ0P8B11
Putative regulatory proteinB195_16809M5QEB31
Putative regulatory protein-RofA relatedSPy_0216Q9A1L01
Putative repressor proteinadcR SPy_0092Q9A1U71
Putative repressor protein PhnRVSAK1_17747A6CVB01
Putative repressor-phage associatedSPy_1861Q99Y571
Putative resistance proteinylcB SSON_0523Q3Z4M01
Putative respiratory nitrate reductase alpha chain (EC 1.7.99.4)narG Smlt2774B2FUL21
Putative respiratory nitrate reductase subunitnarH Smlt2773B2FUL11
Putative response regulatorVSAK1_01297A6D2E51
Putative response regulatorSPy_0245Q9A1J51
Putative response regulatorSPy_1237Q99ZG81
Putative response regulator (Activator) in two-component regulatory system (OmpR family)ACIAD0726Q6FE741
Putative rhamnosyltransferase-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharidergpBc SPy_0787Q9A0G41
Putative ribonucleotide reductase 2nrdF.1 SPy_0425Q9A1771
Putative ribosomal protein S1-like DNA-binding proteinSPy_0913Q9A0661
Putative RmuC family proteinSmlt4678B2FP901
Putative RNA helicasedeaD2 SPy_1369Q99Z691
Putative RNA-binding Sun proteinsunL SPy_1627Q99YM81
Putative RND family (AdeB-like)ACIAD2944Q6F8F61
Putative RND/Acr family transmembrane transportersmeO Smlt3925B2FTS21
Putative rod shape-determining proteinmreB Smlt4059B2FUU01
Putative rRNA methylaseSPy_0356Q9A1C11
Putative rubrerythrinCD630_15240Q18C451
Putative rubrerythrin (Rr)CD630_14740Q18BZ41
Putative salt-induced outer membrane proteinNSU_0049G6E6S81
Putative secreted serine protease (EC 3.4.21.-)Cj1365cQ0P8P41
Putative secretion proteinNMB1737Q7DD871
Putative sensor histidine kinaseCPC_2708B1BMM01
Putative sensory box-containing diguanylate cyclaseCPC_1163B1BJA81
Putative serine protein kinase PrkAB195_20245M5QD221
Putative serine-pyruvate aminotransferase (EC 2.6.1.-)CD630_09940Q18AJ41
Putative shikimate 5-dehydrogenase (EC 1.1.1.25)aroE.2 SPy_0534Q9A1021
Putative short-chain type dehydrogenase/reductase Rv0148 (EC 1.1.1.-)Rv0148P968251
Putative SI family secreted trypsin-like serine proteaseVS_II0815B7VSJ81
Putative siderophore receptorfhuAQ7AX111
Putative sigma 54 modulation proteinyfiA YPO3279Q0WC091
Putative signal peptide peptidase SppA (EC 3.4.21.-)sppA yteI BSU29530O345251
Putative single-strand DNA-specific exonucleaserecJ SPy_0926Q9A0541
Putative SNF helicasesnf SPy_0342Q9A1C91
Putative sodium/solute symporterVSAK1_26655A6D8U81
Putative sodium:dicarboxylate symport transport proteinSmlt3462B2FP321
Putative SpoIIIJ-associated RNA/ssDNA-binding protein Jagjag CD630_36770Q181S91
Putative spore proteinCD630_00070Q18C911
Putative sporulation initiation inhibitor proteinMXAN_5815Q1D0711
Putative sporulation transcription regulator WhiAwhiA SPy_0654 M5005_Spy0541Q9A0R61
Putative structural protein-phage associatedSPy_1457Q99Z071
Putative succinate dehydrogenase iron-sulfur protein (EC 1.3.5.1)sdhB Cj0438Q0PB721
Putative succinate dehydrogenase subunit C (EC 1.3.99.1)sdhC Cj0439Q0PB711
Putative succinic semialdehyde dehydrogenasegabD SPy_1067Q99ZU41
Putative succinyl-diaminopimelate desuccinylaseMXAN_6777Q1CXH91
Putative sucrose operon repressorscrR SPy_1817Q99Y891
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