EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Pyruvate kinase (EC 2.7.1.40)SC1083_0919G4A7X31
Pyruvate kinase (EC 2.7.1.40)pykF SFV_1699Q0T4971
Pyruvate kinase (EC 2.7.1.40)pyk HPSD74_2081U4SA251
Pyruvate kinase (EC 2.7.1.40)pykA SCH_1894Q57NB11
Pyruvate kinase (EC 2.7.1.40)pyk FTT_1366cQ5NF771
Pyruvate kinase (PK) (EC 2.7.1.40)pyk MW1641Q7A0N41
Pyruvate kinase (PK) (EC 2.7.1.40)pyk pykA Rv1617 MTCY01B2.09P9WKE51
Pyruvate kinase (PK) (EC 2.7.1.40)pyk SAOUHSC_01806Q2FXM91
Pyruvate kinase (PK) (EC 2.7.1.40) (Vegetative protein 17) (VEG17)pyk pykA BSU29180P808851
Pyruvate kinase I (EC 2.7.1.40) (PK-1)pykF b1676 JW1666P0AD611
Pyruvate kinase II (EC 2.7.1.40) (PK-2)pykA b1854 JW1843P215991
Pyruvate oxidase, putative (EC 1.2.3.3)SAOUHSC_02849Q2FV861
Pyruvate, phosphate dikinase (EC 2.7.9.1)ppdK FTN_0064A0Q4101
Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)porA_3 porA_1 SAMEA3374989_00900 SAMEA3375059_00046A0A160X9W31
Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)nifJ FSU_0139C9RNZ41
Pyruvate/proton symporter BtsT (Brenztraubensaure transporter) (Pyruvate/H(+) symporter)btsT yjiY b4354 JW5791P393961
Quality control serine endoprotease DegS (EC 3.4.21.-)degS PP_1301Q88NB11
Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)tgt spr1869P669081
Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)tgt PA3823Q9HXH91
Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)tgt SPy_0203 M5005_Spy0175Q9A1L61
Quinate dehydrogenase (Quinone) (EC 1.1.5.8)quiA PP_3569Q88GZ61
Quinolinate phosphoribosyltransferase (EC 2.4.2.19)VSAK1_04695A6D6A21
Quinolone resistance protein NorBnorB SAOUHSC_01448Q2FYJ51
Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase)qor PA0023P439031
Quinoprotein ethanol dehydrogenase (EC 1.1.2.8)qedH-I PP_2674Q88JH51
Quinoprotein glucose dehydrogenase (EC 1.1.5.2)gcd PP_1444Q88MX41
Quinoprotein glucose dehydrogenase-B (Glucose dehydrogenase-B [pyrroloquinoline-quinone]) (Soluble glucose dehydrogenase) (S-GDH) (EC 1.1.5.2)gdhB ABAYE1751B0V5841
RarD proteinVSAK1_24224A6D6J31
RasGEF domain proteinKW89_768A0A0K2DUS41
RasGEF domain proteinKW89_930A0A0K2DVQ81
RCC1 repeat domain proteinMXAN_0889Q1DDX31
RcpArcpA PA4304Q9HW961
RecBCD enzyme subunit RecB (EC 3.1.11.5) (Exonuclease V subunit RecB) (ExoV subunit RecB) (Helicase/nuclease RecBCD subunit RecB)recB FTN_1357A0Q7L71
RecBCD enzyme subunit RecB (EC 3.1.11.5) (Exonuclease V subunit RecB) (ExoV subunit RecB) (Helicase/nuclease RecBCD subunit RecB)recB VSAK1_08601A6D0A31
RecBCD enzyme subunit RecC (EC 3.1.11.5) (Exonuclease V subunit RecC) (ExoV subunit RecC) (Helicase/nuclease RecBCD subunit RecC)recC Fphi_1326B0TXZ01
RecBCD enzyme subunit RecC (EC 3.1.11.5) (Exonuclease V subunit RecC) (ExoV subunit RecC) (Helicase/nuclease RecBCD subunit RecC)recC FTN_1359A0Q7L91
RecBCD enzyme subunit RecD (EC 3.1.11.5) (Exonuclease V subunit RecD) (ExoV subunit RecD) (Helicase/nuclease RecBCD subunit RecD)recD VSAK1_08606A6D0A41
Receptor antigen AragA PGN_0293B2RHG71
Receptor antigen BragB PGN_0294B2RHG81
Recombination protein RecRrecR SPy_1422 M5005_Spy1159P659941
Recombination-associated protein RdgCrdgC YPO3212 y0974 YP_0723Q8ZC181
Redox-sensing transcriptional repressor Rexrex SPy_1120 M5005_Spy0842P603881
Regulator of ribonuclease activity BrraB yjgD b4255 JW4212P0AF901
Regulatory proteinrofA SPy_0124Q9A1S41
Regulatory protein cIISGF_04596E7TIU81
Regulatory protein MsrRmsrR MW1249Q7A0Y41
Regulatory protein MsrRmsrR SAOUHSC_01361Q7BHL71
Regulatory protein RecXrecX SPy_1607 M5005_Spy1320Q99YP21
Regulatory protein SpxspxA SPy_1249 M5005_Spy0959P603811
Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC)prmC AC1_2702B1R7331
Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC)prmC hemK spr0925Q8DPZ31
Replication initiator A, N-terminalSPCG_1340B2IQG81
Replicative DNA helicase (EC 3.6.4.12)dnaB PA4931Q9HUN31
Replicative DNA helicase (EC 3.6.4.12)VSAK1_09223A6D9H81
Replicative DNA helicase (EC 3.6.4.12)holB SPy_2182Q99XJ11
Repressor for uid operonuidR SFV_1634Q0T4F91
Required for phosphorylcholine incorporation in teichoic and lipoteichoic acidslicD1 spr1151Q8DPI01
ResD proteinresDQ8Y5V71
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexEmexE PA2493Q9I0Y91
Respiratory NADH dehydrogenase 2 cupric reductasendh SCH_1161Q57QE41
Respiratory nitrate reductase 2 beta chain (EC 1.7.5.1)narY b1467 JW1462P193181
Respiratory nitrate reductase beta chainnarH PA3874G3XD871
Response regulatorrr08 spr0076Q8DRK11
Response regulatorrr03 spr0344Q8DR451
Response regulatorcomE spr2041Q8DMW51
Response regulatorrr09 spr0578Q8DQN81
Response regulatorVSAK1_06285A6D6Y01
Response regulatorKW89_2268A0A0K2DZ021
Response regulator (Activator) in two-component regulatory system wtih UhpB, regulates uhpT expression (LuxR/UhpA family)KPN_00490A6T5R91
Response regulator ErdRerdR PA3604Q9HY221
Response regulator GacA (Global activator)gacA PA2586Q513731
Response regulator receiver proteinFphi_1209B0TXH61
Response regulator/GGDEF domain proteinMXAN_5340Q1D1I31
RetS (Regulator of Exopolysaccharide and Type III Secretion)retS PA4856Q9HUV71
RgpF, Rhamnan synthesis protein FOOM_0829I2AYR11
Rhamnosyltransferase chain BrhlB PA3478Q9HYD11
Rhizopine catabolism proteinSKA58_02105Q1NH471
RhlEVSAK1_08681A6D9K51
Rhodanese-like domain proteinHPSD74_0770U4SIS11
Rhodanese-like family proteinFTT_1127Q5NFU21
Rhodanese-related sulfurtransferaseFTN_0120A0Q4661
Rhomboid family proteinSAOUHSC_01649Q2FY241
Rhs-related proteinPP_3108Q88I911
Riboflavin biosynthesis protein (EC 2.7.1.26) (EC 2.7.7.2)mreA SPy_1250Q99ZF61
Riboflavin synthase subunit alpha (EC 2.5.1.9)B195_13366M5QZL21
Ribokinase (RK) (EC 2.7.1.15)rbsK b3752 JW3731P0A9J61
Ribokinase (RK) (EC 2.7.1.15)rbsK VSAK1_16162A6CYV01
Ribokinase, PfkB familyFphi_1482B0TYW11
Ribokinase, pfkB familyFTN_1210A0Q7761
Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)rnc spr1127Q8DPJ81
Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)rnc SSON_2691Q3YYU91
Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)rnc acpA SPy_0531 M5005_Spy0438P666701
Ribonuclease E (RNase E) (EC 3.1.26.12)rne Fphi_1434B0TYI31
Ribonuclease E (RNase E) (EC 3.1.26.12)rne SC1083_1969G4AAU01
Ribonuclease E (RNase E) (EC 3.1.26.12)rne KPR_2129R4Y8821
Ribonuclease E (RNase E) (EC 3.1.26.12)rne ams hmp1 b1084 JW1071P215131
Ribonuclease E (RNase E) (EC 3.1.26.12)rne HPSD74_1168U4SGJ21
Ribonuclease E (RNase E) (EC 3.1.26.12)rne OOM_1576I2B0L01
Ribonuclease E (RNase E) (EC 3.1.26.12)rne KU39_1035A0A0K2L2381
Ribonuclease E (RNase E) (EC 3.1.26.12)rne FTT_1227Q5NFK71
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