EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Secreted effector kinase SteC (EC 2.7.-.-) (Salmonella translocated effector C)steC STM1698Q8ZP571
Secreted effector protein SptP [Includes: GTPase-activating protein (GAP); Tyrosine-protein phosphatase (EC 3.1.3.48)]sptP STM2878P748731
Secreted effector protein SseB (Secretion system effector B)sseB STM1398Q7BVH71
Secreted effector protein SseC (Secretion system effector C)sseC STM1400O849471
Secreted effector protein SseD (Secretion system effector D)sseD STM1401Q9R8031
Secreted effector protein SteA (Salmonella translocated effector A)steA STM1583Q8ZPD71
Secreted flagellin CflaC Cj0720cP967471
Secreted metalloprotease Mcp02 (EC 3.4.24.-)KW89_3040A0A0K2E1401
Secretion proteinFTT_0018Q5NIP81
Secretion protein HlyDB195_10851M5QIS61
Segregation and condensation protein AscpA SPy_0366 M5005_Spy0308Q9A1B21
Segregation and condensation protein BscpB SPy_0367 M5005_Spy0309P602201
Sel1-like protein (EC 3.5.2.6)OOM_0265I2AXC31
Selenocysteine-specific translation elongation factorselB MXAN_1076Q1DDD71
Sensor histidine kinaseMXAN_5314Q1D1K81
Sensor histidine kinaseLMRG_00830A0A0H3GBY41
Sensor histidine kinase (EC 2.7.13.3)SPy_1622Q99YN21
Sensor histidine kinase (EC 2.7.3.-)qseC FTT_0094cQ5NIH61
Sensor histidine kinase ResELMRG_01094A0A0H3GE391
Sensor histidine kinase/response rgulatorMXAN_4465Q1D3Y71
Sensor protein PhoQ (EC 2.7.13.3) (EC 3.1.3.-) (Sensor histidine protein kinase/phosphatase PhoQ)phoQ b1129 JW1115P238371
Sensor protein SrrB (EC 2.7.13.3) (Staphylococcal respiratory response protein B)srrB SAOUHSC_01585Q2FY801
Sensory box histidine kinase/response regulatorMXAN_6855Q1CXA11
Septation ring formation regulator EzrAezrA SAOUHSC_01827Q2FXK81
SerAserA HPSD74_1240U4SHG71
Serine acetyltransferase (EC 2.3.1.30)cysE CJD_1771B1V8541
Serine acetyltransferase (EC 2.3.1.30)cysE spr0517Q8DQS91
Serine endoproteasedegQ KPN_03633A6TEP21
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA MW2037P668041
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA Fphi_1424B0TYH31
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA FTN_1259A0Q7C51
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA KPN78578_28250 KPN_02876A6TCG51
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA NMB1055P569901
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA glyC BSU36900 ipc-34dP391481
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA YPO2907 y1322 YP_2548Q8ZCR11
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA SF2598 S2770P0A8271
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA SC1083_1340G4A9321
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA b2551 JW2535P0A8251
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA HPSD74_0422U4SMB51
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA SPy_1145 M5005_Spy0867Q99ZP11
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA glyA_1 glyA_2 BN1095_20264 BN1096_690008 BN1097_700008 SAMEA3374973_03801 SAMEA3374989_00952 SAMEA3375004_02364 SAMEA3375059_01881A0A069AKK11
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA OOM_1564I2B0J91
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA SCH_2549Q57LF71
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA SAOUHSC_02354Q2FWE51
Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)glyA FTT_1241Q5NFJ31
Serine hydroxymethyltransferase 1 (SHM1) (SHMT 1) (Serine methylase 1) (EC 2.1.2.1)glyA1 glyA Rv1093 MTV017.46P9WGI91
Serine hydroxymethyltransferase 2 (SHMT 2) (Serine methylase 2) (EC 2.1.2.1)glyA2 PA2444Q9I1381
Serine O-acetyltransferaseB195_00045M5QN581
Serine peptidase, S49 familyFTN_0118A0Q4641
Serine protease (EC 3.4.21.-)AC3_2825B1BRP81
Serine protease Do-like HtrB (EC 3.4.21.107) (HtrA-like serine protease)htrB yvtA BSU33000Q9R9I11
Serine protease espP (EC 3.4.21.-)espP HPSD74_1531U4SF141
Serine protease HtrA-like (EC 3.4.21.-)SAOUHSC_00958Q2FZP21
Serine protease pic autotransporter (EC 3.4.21.-) [Cleaved into: Serine protease pic; Serine protease pic translocator]pic she c0350Q8CWC71
Serine protease Rv3671c (EC 3.4.21.-)Rv3671cP9WHR91
Serine protease sat autotransporter (EC 3.4.21.-) [Cleaved into: Serine protease sat (Secreted autotransporter toxin sat); Serine protease sat translocator]sat c3619Q8FDW41
Serine protease SepA autotransporter (EC 3.4.21.-) [Cleaved into: Serine protease SepA; Serine protease SepA translocator]sepA CP0070Q8VSL21
Serine protease, HrtA family (EC 3.4.21.-)CD630_32840Q180C81
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS Fphi_0173B0TYM91
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS FTN_0647A0Q5M51
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS YPO1379 y2796 YP_1214Q8ZGC41
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS SF0852 S0893P0A8L41
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS PA2612Q9I0M61
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS b0893 JW0876P0A8L11
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS SPy_1742 M5005_Spy1483Q99YE21
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS1 serS CD630_00140Q18C971
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)serS SCH_0917Q57R381
Serine-aspartate repeat-containing protein DsdrD SAOUHSC_00545Q2G0L41
Serine-rich adhesin for platelets (Staphylococcus aureus surface protein A)sraP sasA SAOUHSC_02990Q2FUW11
Serine-type D-Ala-D-Ala carboxypeptidaseFTN_0635A0Q5L31
Serine-type D-Ala-D-Ala carboxypeptidaseB195_13161M5QHW11
Serine-type D-Ala-D-Ala carboxypeptidase (EC 3.4.16.4)Fphi_1708B0U0A31
Serine-type D-Ala-D-Ala carboxypeptidase (EC 3.4.16.4)OOM_0962I2AZ291
Serine-type D-Ala-D-Ala carboxypeptidase (EC 3.4.16.4)OOM_0970I2AZ371
Serine-type peptidaseNMB1998Q9JXK31
Serine/threonine kinase associate protein KapCkapC MXAN_1668Q1DBQ31
Serine/threonine kinase family protein (EC 2.7.1.-)MXAN_4557Q1D3P81
Serine/threonine protein kinase PpkAppkA PA0074Q9I7581
Serine/threonine transporter SstT (Na(+)/serine-threonine symporter)sstT PP_2443Q88K491
Serine/threonine transporter SstT (Na(+)/serine-threonine symporter)sstT SPy_0324 M5005_Spy0275Q9A1E01
Serpin (Serine proteinase inhibitor) family proteinMXAN_4276Q1D4H21
Shiga toxin 2 A-subunit (Shiga toxin 2 subunit A) (Shiga-like toxin II A subunit encoded by bacteriophage BP-933W)stx2 A-subunit stx 2 A-subunit stx2A ECs1205 Z1464Q7DI681
Shiga toxin 2 subunit AstxA2Q6YII81
Shiga toxin 2 subunit BstxB2Q6YII71
Shiga toxin 2 subunit B (Shiga-like toxin II B subunit encoded by bacteriophage BP-933W) (Stx2 subunit B)stx2B ECs1206 Z1465A7UQX31
Shikimate dehydrogenase (NADP(+)) (SDH) (EC 1.1.1.25)aroE SPy_1584 M5005_Spy1303P635971
Shikimate kinase (SK) (EC 2.7.1.71)aroK FTN_1136A0Q7071
Shikimate kinase (SK) (EC 2.7.1.71)aroK SPy_1351Q99Z841
Short chain dehydrogenaseFphi_1807B0U0T11
Short chain dehydrogenaseFTN_0807A0Q6301
Short chain dehydrogenaseFTN_0957A0Q6I01
Short chain dehydrogenaseB195_03803M5QPP71
Short chain dehydrogenase family proteinKW89_58A0A0K2DT371
Short-chain dehydrogenaseFTN_1178A0Q7491
Short-chain dehydrogenase/reductase (EC 1.-.-.-)FTT_0360Q5NHT51
Short-chain dehydrogenase/reductase SDRB195_15959M5QFB21
Sialidase (EC 3.2.1.18) (Neuraminidase) (NANase)nanH VC_1784P0C6E91
Sialidase B (Neuraminidase B) (EC 3.2.1.18)nanB spr1531Q8CWP81
Sigma factor-binding protein Crlcrl VSAK1_02084A6D9N61
Sigma-54 dependent transcriptional regulatorVSAK1_11178A6D8T61
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