| Signal peptidase I (EC 3.4.21.89) | lepB FTN_1464 | A0Q7W7 | 1 |
| Signal peptidase I (EC 3.4.21.89) | B195_05556 | M5QNE6 | 1 |
| Signal peptidase I (EC 3.4.21.89) | AC1_0338 | B1R802 | 1 |
| Signal peptidase I (EC 3.4.21.89) | lepB PP_1432 | Q88MY6 | 1 |
| Signal peptidase I (EC 3.4.21.89) | SC1083_1794 | G4AAC1 | 1 |
| Signal peptidase I (EC 3.4.21.89) | lepB HPSD74_0075 | U4SPB6 | 1 |
| Signal peptidase I (EC 3.4.21.89) | VSAK1_07959 | A6D8G2 | 1 |
| Signal peptidase I (EC 3.4.21.89) | sip2 CD630_05540 | Q188Z9 | 1 |
| Signal peptidase I (EC 3.4.21.89) | spsB_3 spsB_1 SAMEA3374989_02348 SAMEA3375059_00994 | A0A160WAT8 | 1 |
| Signal peptidase I (EC 3.4.21.89) | OOM_0761 | I2AYK1 | 1 |
| Signal peptidase I (EC 3.4.21.89) | SAOUHSC_00903 | Q2FZT7 | 1 |
| Signal peptidase I (EC 3.4.21.89) | SAOUHSC_00902 | Q2FZT8 | 1 |
| Signal peptidase I (EC 3.4.21.89) | lepB FTT_1556c | Q5NER2 | 1 |
| Signal peptidase I U (SPase I) (EC 3.4.21.89) (Leader peptidase I) | sipU ycsB BSU04010 | P42959 | 1 |
| Signal peptide protein | N173_18140 | U1UEH0 | 1 |
| Signal recognition particle protein (Fifty-four homolog) | ffh PP_1461 | Q88MV7 | 1 |
| Signal recognition particle protein (Fifty-four homolog) | ffh HPSD74_1589 | U4SEQ3 | 1 |
| Signal recognition particle protein (Fifty-four homolog) | ffh Smlt1371 | B2FUB0 | 1 |
| Signal recognition particle protein (Fifty-four homolog) | ffh SPy_1200 | Q99ZK1 | 1 |
| Signal recognition particle protein (Fifty-four homolog) | ffh BN1095_790028 BN1096_560167 BN1097_540171 SAMEA3375004_00151 SAMEA3375059_02492 | A0A031WDB6 | 1 |
| Signal recognition particle protein (Fifty-four homolog) | ffh SAOUHSC_01207 | Q2FZ46 | 1 |
| Signal recognition particle protein (Fifty-four homolog) | ffh FTT_0964c | Q5NG88 | 1 |
| Signal recognition particle receptor FtsY (SRP receptor) | ftsY PA0373 | Q9I6C1 | 1 |
| Signal recognition particle receptor FtsY (SRP receptor) | ftsY VSAK1_12405 | A6D6X2 | 1 |
| Signal recognition particle receptor FtsY (SRP receptor) | ftsY SPy_0569 | Q9A0X7 | 1 |
| Signal recognition particle receptor FtsY (SRP receptor) | ftsY OOM_0612 | I2AY75 | 1 |
| Signal transduction histidine kinase | NSU_2852 | G6EET1 | 1 |
| Signal transduction histidine-protein kinase AtoS (EC 2.7.13.3) | atoS b2219 JW2213 | Q06067 | 1 |
| Signal transduction protein TRAP (Target of RNAIII-activating protein) | traP SAOUHSC_01964 | Q2G2F3 | 1 |
| Signal transduction protein with a PAS, a PAC, an EAL and a GGDEF domain | FTN_0451 | A0Q539 | 1 |
| Simple sugar transport system permease | LMRG_00843 | A0A0H3GCJ3 | 1 |
| Single-stranded DNA-binding protein (SSB) | ssb jhp_1166 | Q9ZJY2 | 1 |
| Single-stranded DNA-binding protein (SSB) | Fphi_0702 | B0TW15 | 1 |
| Single-stranded DNA-binding protein (SSB) | ssb FTN_0124 | A0Q470 | 1 |
| Single-stranded DNA-binding protein (SSB) | ssb MXAN_1071 | Q1DDE2 | 1 |
| Single-stranded DNA-binding protein (SSB) | ssb Rv0054 MTCY21D4.17 | P9WGD5 | 1 |
| Single-stranded DNA-binding protein (SSB) | HPSD74_0413 | U4SLL8 | 1 |
| Single-stranded DNA-binding protein (SSB) | ssb3 ssb SPy_1830 M5005_Spy1554 | P66852 | 1 |
| Single-stranded DNA-binding protein (SSB) | ssb1 CD630_36620 | Q181R6 | 1 |
| Single-stranded DNA-binding protein (SSB) | OOM_0102 | I2AWW8 | 1 |
| Single-stranded DNA-binding protein (SSB) | ssb FTT_1752 | Q5NE96 | 1 |
| Siroheme synthase 1 [Includes: Uroporphyrinogen-III C-methyltransferase 1 (Urogen III methylase 1) (EC 2.1.1.107) (SUMT 1) (Uroporphyrinogen III methylase 1) (UROM 1); Precorrin-2 dehydrogenase 1 (EC 1.3.1.76); Sirohydrochlorin ferrochelatase 1 (EC 4.99.1.4)] | cysG1 KPN78578_30550 KPN_03115 | A6TD45 | 1 |
| Site-determining protein | B195_20220 | M5QD18 | 1 |
| Site-determining protein | fleN PA1454 | G3XD64 | 1 |
| Site-determining protein | OOM_0313 | I2AXG4 | 1 |
| Site-determining protein | minD FTT_1606 | Q5NEM0 | 1 |
| Site-specific recombinase | SPCG_1274 | B2IQA6 | 1 |
| Site-specific recombinase, phage integrase family | EDWATA_02641 | D4F7A6 | 1 |
| Small heat shock protein IbpA | ibpA PP_1982 | Q88LF1 | 1 |
| Small ribosomal subunit biogenesis GTPase RsgA (EC 3.6.1.-) | rsgA SPy_0263 M5005_Spy0223 | Q9A1H9 | 1 |
| Small toxic protein ShoB | shoB ryfB yphI b4687 JW2546.1 | C1P611 | 1 |
| Small toxic protein TisB (LexA-regulated protein TisB) | tisB ysdB b4618 JW3649 | A5A627 | 1 |
| Small-conductance mechanosensitive channel | mscS yggB b2924 JW2891 | P0C0S1 | 1 |
| SN-glycerol-3-phosphate ABC transporter, permease protein | VSAK1_01337 | A6D2F3 | 1 |
| sn-glycerol-3-phosphate acyltransferase | plsD AC3_1724 | B1BX74 | 1 |
| sn-glycerol-3-phosphate import ATP-binding protein UgpC (EC 3.6.3.20) | ugpC VSAK1_01327 | A6D2F1 | 1 |
| sn-glycerol-3-phosphate transport system permease protein UgpE | ugpE VSAK1_01332 | A6D2F2 | 1 |
| sn-glycerol-3-phosphate-binding periplasmic protein UgpB | ugpB STM3557 | Q7CPK0 | 1 |
| Snf2 family protein | SPCG_1597 | B2IRD0 | 1 |
| Social gliding motility protein Tgl | tgl MXAN_3084 | Q1D7T6 | 1 |
| Sodium transport system ATP-binding protein | LMRG_02801 | A0A0H3GEL0 | 1 |
| Sodium, sulfate symporter, putative | SAOUHSC_03030 | Q2FUS2 | 1 |
| Sodium-calcium/proton antiporter | chaA KPN_02229 | A6TAN4 | 1 |
| Sodium-dependent dicarboxylate transporter SdcS (Na(+)/dicarboxylate symporter) | sdcS SAOUHSC_02137 | Q2FWY4 | 1 |
| Sodium-dependent transporter (Fragment) | VSAK1_12140 | A6D860 | 1 |
| Sodium-dicarboxylate symporter family protein | FTT_0598c | Q5NH71 | 1 |
| Sodium/alanine symporter | VS_0633 | B7VJV2 | 1 |
| Sodium/alanine symporter | PP_0496 | Q88QJ5 | 1 |
| Sodium/alanine symporter | VSAK1_12000 | A6D2X6 | 1 |
| Sodium/glutamate symporter | gltS VSAK1_19574 | A6CWJ5 | 1 |
| Sodium/glutamate symporter | SAOUHSC_02622 | Q2FVS0 | 1 |
| Sodium/hydrogen exchanger (Antiporter) family protein | FTT_0268 | Q5NI22 | 1 |
| Sodium/hydrogen exchanger family protein | MXAN_3848 | Q1D5P3 | 1 |
| Sodium/hydrogen exchanger family protein | KW89_1738 | A0A0K2DY00 | 1 |
| Sodium/proline symporter (Proline permease) | putP SAOUHSC_02119 | Q2FWY7 | 1 |
| Sodium/proline symporter (Proline permease) (Propionate transporter) | putP b1015 JW1001 | P07117 | 1 |
| Sodium/solute symporter family protein | AC3_0107 | B1BXE1 | 1 |
| Sodium/solute symporter family protein | AC3_0300 | B1BS11 | 1 |
| Sodium:alanine symporter family protein | AC3_2497 | B1BPW3 | 1 |
| Sodium:alanine symporter family protein, putative | SAOUHSC_01354 | Q2G2N5 | 1 |
| Sodium:dicarboxylate symporter family protein | CPC_1216 | B1BHD9 | 1 |
| Sodium:neurotransmitter symporter family protein | CPC_1604 | B1BFG4 | 1 |
| Sodium:proton exchanger | KU39_1592 | A0A0K2L3P7 | 1 |
| Soluble lytic murein transglycosylase | Fphi_0355 | B0TZL3 | 1 |
| Soluble lytic murein transglycosylase | VSAK1_14102 | A6D3P6 | 1 |
| Soluble lytic murein transglycosylase | OOM_1057 | I2AZA8 | 1 |
| Soluble lytic murein transglycosylase (EC 3.2.1.-) | slt FTT_0400 | Q5NHP7 | 1 |
| Soluble lytic murein transglycosylase (EC 4.2.2.n1) (Exomuramidase) (Peptidoglycan lytic exotransglycosylase) (Slt70) | slt sltY b4392 JW4355 | P0AGC3 | 1 |
| Soluble pyridine nucleotide transhydrogenase | Fphi_1588 | B0TZF9 | 1 |
| Soluble pyridine nucleotide transhydrogenase | udhA FTN_0999 | A0Q6M2 | 1 |
| Soluble pyridine nucleotide transhydrogenase (STH) (EC 1.6.1.1) (NAD(P)(+) transhydrogenase [B-specific]) | sthA udhA KPN78578_42060 KPN_04251 | A6TGE6 | 1 |
| Soluble pyridine nucleotide transhydrogenase (STH) (EC 1.6.1.1) (NAD(P)(+) transhydrogenase [B-specific]) | sthA B195_19626 | M5QD74 | 1 |
| Soluble pyridine nucleotide transhydrogenase (STH) (EC 1.6.1.1) (NAD(P)(+) transhydrogenase [B-specific]) | sthA sth udhA b3962 JW5551 | P27306 | 1 |
| Soluble pyridine nucleotide transhydrogenase (STH) (EC 1.6.1.1) (NAD(P)(+) transhydrogenase [B-specific]) | sthA VSAK1_13256 | A6D954 | 1 |
| Soluble secreted antigen MPT53 | mpt53 mpb53 Rv2878c MTCY274.09c | P9WG65 | 1 |
| Sortase A, LPXTG specific | pCpb2-CP1_61 | K9MGG2 | 1 |
| Sortase B | AC3_0625 | B1BNC4 | 1 |
| Sortase family protein | CP4_3470 | F8UNK0 | 1 |
| Sortase family protein | CPC_2651 | B1BMR7 | 1 |
| Sortase, putative | SAOUHSC_02834 | Q2FV99 | 1 |