EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Trehalose synthase/amylase TreS (EC 3.2.1.1) (EC 5.4.99.16) (Maltose alpha-D-glucosyltransferase) (MTase)treS Rv0126P9WQ191
Trehalose-6-phosphate hydrolase (EC 3.2.1.93) (Alpha,alpha-phosphotrehalase)treC olgH b4239 JW4198P289041
Trifunctional UDP-D-GlcNAc 4,6-dehdratase/5-epimerase/3-epimeraseSP70585_0424C1CBD91
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig Fphi_1531B0TZA41
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig KPN78578_03890 KPN_00398A6T5H91
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig CJD_0163B1V7P41
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig spr0362Q8DR291
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig YPO3158 y1026 YP_0773Q8ZC641
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig SF0381 S0387P0A8521
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig SC1083_1827G4AAF41
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig b0436 JW0426P0A8501
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig SSON_0419Q3Z4W71
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig ropA SPy_1896 M5005_Spy1612P0C0E11
Trigger factor (TF) (EC 5.2.1.8) (PPIase)tig SAOUHSC_01779Q2FXQ61
Triosephosphate isomerase (EC 5.3.1.1)VSAK1_00577A6D1761
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA Fphi_0977B0TWU21
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA FTN_1631A0Q8C41
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA STM4081Q8ZKP71
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA YPO0085 y0052 YP_0089Q8ZJK91
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA tpi Rv1438 MTCY493.16cP9WG431
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA SC1083_1668G4A9Z51
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA tpi b3919 JW3890P0A8581
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA tpi SPy_0613 M5005_Spy0509P698871
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA tpi BN1095_560008 BN1096_720012 BN1097_730012 SAMEA3374989_01377 SAMEA3375004_02829 SAMEA3375059_02347A0A031WLR91
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)tpiA FSU_2922C9RL061
Trk transporter membrane-spanning protein-K+ transporttrkH spr0070Q8DRK51
Trk transporter NAD+ binding protein-K+ transporttrkA spr0427Q8DQY81
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ (EC 2.1.1.200) (tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase) (tRNA Cm32/Um32 methyltransferase)trmJ FTN_1294A0Q7G01
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ (EC 2.1.1.200) (tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase) (tRNA Cm32/Um32 methyltransferase)trmJ yfhQ b2532 JW2516P0AE011
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ (EC 2.1.1.200) (tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase) (tRNA Cm32/Um32 methyltransferase)trmJ VSAK1_12125A6D3011
tRNA (guanine-N(1)-)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase)trmD SPy_0849 M5005_Spy0656Q9A0B61
tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase)trmB SPy_1726 M5005_Spy1468P675041
tRNA 2-selenouridine synthase (EC 2.9.1.-) (Selenophosphate-dependent tRNA 2-selenouridine synthase)selU PA1643Q9I3821
tRNA dimethylallyltransferase (EC 2.5.1.75) (Dimethylallyl diphosphate:tRNA dimethylallyltransferase) (DMAPP:tRNA dimethylallyltransferase) (DMATase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (IPTase)miaA VSAK1_09968A6D8D41
tRNA dimethylallyltransferase (EC 2.5.1.75) (Dimethylallyl diphosphate:tRNA dimethylallyltransferase) (DMAPP:tRNA dimethylallyltransferase) (DMATase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (IPTase)miaA SPy_0921 M5005_Spy0722Q9A0591
tRNA modification GTPase MnmE (EC 3.6.-.-)mnmE thdF trmE SPy_1071 M5005_Spy0794Q99ZU01
tRNA modification GTPase MnmE (EC 3.6.-.-)mnmE trmE LMRG_01887A0A0H3GGM71
tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD) (tRNA threonylcarbamoyladenosine biosynthesis protein TsaD)tsaD gcp SPy_1872 M5005_Spy1591Q99Y461
tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)truA SPy_1901 M5005_Spy1617P658501
tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)truA2 truA CD630_17840Q186Z41
tRNA pseudouridine synthase B (EC 5.4.99.25) (tRNA pseudouridine(55) synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)truB VSAK1_10983A6D2441
tRNA pseudouridine synthase B (EC 5.4.99.25) (tRNA pseudouridine(55) synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)truB SPy_1251 M5005_Spy0961P658581
tRNA pseudouridine synthase C (EC 5.4.99.26) (tRNA pseudouridine(65) synthase) (tRNA pseudouridylate synthase C) (tRNA-uridine isomerase C)truC YPO1038 y3143 YP_2813Q8ZH721
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG (Glucose-inhibited division protein A)mnmG gidA spr0124Q8DRH81
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG (Glucose-inhibited division protein A)mnmG gidA SPy_2185 M5005_Spy1838Q99XI81
tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase)mesJ tilS SSON_0201Q3Z5G91
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (EC 2.8.4.3) ((Dimethylallyl)adenosine tRNA methylthiotransferase MiaB) (tRNA-i(6)A37 methylthiotransferase)miaB PA3980Q514701
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (EC 2.8.4.3) ((Dimethylallyl)adenosine tRNA methylthiotransferase MiaB) (tRNA-i(6)A37 methylthiotransferase)miaB VSAK1_11405A6D9051
tRNA-dihydrouridine synthase (EC 1.3.1.-)spr1994Q8DN061
tRNA-dihydrouridine synthase (EC 1.3.1.-)SP70585_2315C1CBG51
tRNA-dihydrouridine synthase (EC 1.3.1.-)SPy_0122Q7DAN31
tRNA-modifying protein YgfZYPO0898 y3283 YP_3595Q7CGT31
tRNA-modifying protein YgfZygfZ yzzW b2898 JW2866P0ADE81
tRNA-specific 2-thiouridylase MnmA (EC 2.8.1.13)mnmA trmU Fphi_0719B0TW321
tRNA-specific 2-thiouridylase MnmA (EC 2.8.1.13)mnmA trmU SPy_2188 M5005_Spy1840P580751
tRNA-specific 2-thiouridylase MnmA (EC 2.8.1.13)mnmA asuE trmU ycfB b1133 JW1119P257451
tRNA-specific adenosine deaminase (EC 3.5.4.33)tadA SPy_0209 M5005_Spy0179P689991
Trp operon repressor homologtrpR VSAK1_14107A6D3P71
Trp repressor binding proteinFphi_0639B0U1421
Trypsin family protein (EC 3.4.21.-)KW89_2954A0A0K2E1J51
Trypsin like proteinase PrtTprtT PGN_0561B2RI851
Trypsin, putativeVC_1649Q9KRJ11
Tryptophan 2,3-dioxygenase family protein (EC 1.13.11.11)KW89_436A0A0K2DU721
Tryptophan synthase alpha chain (EC 4.2.1.20)trpA PP_0082Q88RP71
Tryptophan synthase alpha chain (EC 4.2.1.20)trpA b1260 JW1252P0A8771
Tryptophan synthase alpha chain (EC 4.2.1.20)trpA SFV_1274Q0T5D61
Tryptophan synthase beta chain (EC 4.2.1.20)trpB NMB0699Q9K0B51
Tryptophan synthase beta chain (EC 4.2.1.20)trpB Rv1612 MTCY01B2.04P9WFX91
Tryptophan synthase beta chain (EC 4.2.1.20)trpB b1261 JW1253P0A8791
Tryptophan--tRNA ligase (EC 6.1.1.2)Fphi_1142B0TXA81
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)trpS STM3481P0A2P21
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)trpS b3384 JW3347P009541
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)trpS VSAK1_09343A6D7781
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)trpS trsA SPy_2207 M5005_Spy1858Q99XH41
Twin-arginine translocation pathway signalNSU_4099G6EIC71
Twitching mobility proteinpilT PA0395P245591
Twitching motility protein PilTpilT FSU_1505C9RPX91
Two component regulator propeller family proteinFSU_2254D9S4231
Two component regulator three Y motif proteinCPC_2570B1BMZ61
Two component regulator, sensor histidine kinase kdpDkdpD FTN_1715A0Q8K71
Two component sensor protein kdpD (EC 2.7.3.-)kdpD FTT_1736cQ5NEA71
Two-component regulatorCj0355cQ0PBF41
Two-component regulatorracR Cj1261Q0P8Z51
Two-component regulator, sensor histidine kinaseFTN_1617A0Q8B11
Two-component regulator, sensor histidine kinase (EC 2.7.13.3)OOM_0590I2AY561
Two-component response regulatorFTN_1465A0Q7W81
Two-component response regulatorvicR SPy_0528Q9A1081
Two-component response regulatorCD630_30540Q184P21
Two-component response regulatorFTT_1557cQ5NER11
Two-component response regulator CbrBcbrB PA4726Q9HV731
Two-component sensor CbrAcbrA PA4725Q9HV741
Two-component sensor histidine kinasevicK SPy_0529Q9A1071
Two-component sensor PhoQphoQ PA1180Q9I4F81
Two-component sensor protein (Fragment)cpxA VSAK1_24159A6D9U91
Two-component signal transduction histidine kinaseNSU_0273G6E7D81
Type 4 fimbrial assembly protein PilBpilB PA4526P226081
Type 4 fimbrial biogenesis protein FimUfimU PA4550G3XCZ01
Type 4 fimbrial biogenesis protein PilPpilP PA5041G3XCX71
Type 4 fimbrial biogenesis protein PilXpilX PA4553Q9HVM91
Type 4 pilus biogenesis operon proteinMXAN_0359Q1DFE01
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