EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Uncharacterized proteinLMRG_00479A0A0H3GAX94
Uncharacterized proteinLMRG_00530A0A0H3GB204
Uncharacterized proteinLMRG_00783A0A0H3GBV04
Uncharacterized proteinLMRG_01441A0A0H3GKG14
Uncharacterized proteinLMRG_01459A0A0H3GGG34
Uncharacterized proteinLMRG_01508A0A0H3GEI44
Uncharacterized proteinLMRG_01513A0A0H3GEI34
Uncharacterized proteinLMRG_01603A0A0H3GMF94
Uncharacterized proteinLMRG_01318A0A0H3GD564
Uncharacterized protein PA3922PA3922Q9HX914
Uncharacterized protein YcbKycbK Z1273 ECs1009P0AB084
UPF0149 protein YgfBygfB BX51_15360A0A025CHU74
Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase)upp NGO0353Q5F9P04
Urease subunit alpha (EC 3.5.1.5) (Urea amidohydrolase subunit alpha)ureA hpuA HP_0073P149164
Urease subunit beta (EC 3.5.1.5) (Urea amidohydrolase subunit beta)ureB hpuB HP_0072P699964
Uridine kinase (EC 2.7.1.48) (Cytidine monophosphokinase) (Uridine monophosphokinase)udk Z3234 ECs2873P0A8F64
Uridine kinase (EC 2.7.1.48) (Cytidine monophosphokinase) (Uridine monophosphokinase)udk BY96_25845A0A027U5G54
Uridine phosphorylase (UPase) (UrdPase) (EC 2.4.2.3)udp b3831 JW3808P127584
Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)hemE NGO0362Q5F9N14
Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)hemE BY96_20180A0A027TLK84
UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)uvrA NGO_1207Q5F7H14
Valine--pyruvate aminotransferase (EC 2.6.1.66) (Valine--pyruvate transaminase)avtA A4T40_23650 BK248_14900 BK334_07480 ECONIH1_20840 MS6198_41060A0A0A1AG884
Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)valS PA3834Q9HXH04
Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)valS NGO1809Q5F5W04
YSIRK family Signal peptideNGO_0666Q5F8U44
(R,R)-butanediol dehydrogenase (EC 1.1.1.4) (Acetoin reductase/2,3-butanediol dehydrogenase) (AR/BDH)bdhA ydjL BSU06240O347883
1,2-propanediol oxidoreductase (Lactaldehyde reductase)BE932_11945 SY51_15695A0A061YM883
1,5-anhydro-D-fructose reductase (Oxidoreductase)afr_2 A4T40_21090 BK334_10080 ECONIH1_18330 MS6198_35660 SY51_17885A0A061YDE83
1,6-anhydro-N-acetylmuramyl-L-alanine amidase (EC 3.5.1.28)amiD PP_0130Q88RJ93
10 kDa chaperonin (GroES protein) (Heat shock protein 10) (Protein Cpn10)groS groES hsp10 hspA mopB HP_0011P0A0R33
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)dapD PA3666G3XD763
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)dapD EcE24377A_0169A7ZHQ63
2,5-diketo-D-gluconate reductase A (EC 1.1.1.274)dkgA ECED1_3662B7N0E33
2,5-diketo-D-gluconic acid reductase (Glyoxal reductase) (Putative aldo/keto reductase) (EC 1.1.1.-)yvgN_2 yvgN_1 A4T40_04815 A4T50_25360 BE932_25130 BE963_15595 BET08_14810 BK248_05040 BK334_06385 BK375_21250 BK383_16585 BMT49_02760 BMT97_17975 BUE82_19195 ECONIH1_01785 ERS085406_03758 MS6198_03030 SY51_01665 UC41_02130 WM48_01860E2QG623
2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (EC 2.3.1.29) (Glycine acetyltransferase)kbl BY96_26225A0A027TD113
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECDP-synthase) (MECPP-synthase) (MECPS) (EC 4.6.1.12)ispF ECED1_3202B7MZ473
2-deoxyglucose-6-phosphatase (2-deoxyglucose-6-phosphate phosphatase)A4T50_01125 APU18_09530 BE932_04090 BK373_05105 MJ49_22710 SY51_09610 WM48_08830A0A067HGC73
2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)sucA b0726 JW0715P0AFG33
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB (EC 2.1.1.185) (23S rRNA (guanosine2251 2'-O)-methyltransferase) (23S rRNA Gm2251 2'-O-methyltransferase)rlmB BY96_00595A0A027U4U43
3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (CMP-2-keto-3-deoxyoctulosonic acid synthase) (CKS) (CMP-KDO synthase)kdsB AC067_07905 BE932_28840 SY51_05215A0A061KWL13
3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (CMP-2-keto-3-deoxyoctulosonic acid synthase) (CKS) (CMP-KDO synthase)kpsU kdsB ACN87_12525 ECONIH1_17510 MS6198_34050A0A0A1A9A93
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (17 kDa actomyosin component) (Beta-hydroxyacyl-ACP dehydratase)fabZ sefA yaeA b0180 JW0175P0A6Q63
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA) (Beta-hydroxydecanoyl thioester dehydrase) (Trans-2-decenoyl-[acyl-carrier-protein] isomerase) (EC 5.3.3.14)fabA EcE24377A_1068A7ZK573
3-ketoacyl-acyl carrier protein reductase (EC 1.1.1.100)fabG spr0381Q8DR153
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Fatty acid oxidation complex subunit beta)fadA A5958_09645 AA102_11475 ACN77_18100 BE957_02865 BMT61_12740 ERS085379_03141 GJ12_23705 HW42_00715 PU06_16930 RG28_24540 UN86_04770 WQ89_13355A0A066R6J43
3-methyladenine DNA glycosylase (DNA-3-methyladenine glycosylase 1) (DNA-3-methyladenine glycosylase I)tag A4T40_23530 BE949_22455 BE963_08875 BIQ85_19945 BK248_20195 BK334_07355 BK373_23150 BMT97_18785 BXT93_08055 ECONIH1_20715 MJ49_12445 MS6198_40750A0A023KV363
30S ribosomal protein S1rpsA FTN_0159A0Q4A43
30S ribosomal protein S1 (Bacteriophage Q beta RNA-directed RNA polymerase subunit I) (Small ribosomal subunit protein bS1)rpsA ssyF b0911 JW0894P0AG673
30S ribosomal protein S10rpsJ spr0187P663403
30S ribosomal protein S11rpsK Smlt0929B2FQK63
30S ribosomal protein S12rpsL EcE24377A_3811A7ZSL73
30S ribosomal protein S13rpsM PP_0476Q88QL33
30S ribosomal protein S14rpsN PA4250Q9HWE83
30S ribosomal protein S18rpsR PA4934Q9HUN03
30S ribosomal protein S18rpsR G925_04532A0A0E2KXL33
30S ribosomal protein S19rpsS CKO_04732A8AQL33
30S ribosomal protein S2 (BS1) (Vegetative protein 209) (VEG209)rpsB BSU16490P214643
30S ribosomal protein S2 (Small ribosomal subunit protein uS2)rpsB b0169 JW0164P0A7V03
30S ribosomal protein S20rpsT PP_0600Q88Q953
30S ribosomal protein S20rpsT EcE24377A_0023A7ZHB23
30S ribosomal protein S3rpsC PP_0460Q88QM93
30S ribosomal protein S3 (Small ribosomal subunit protein uS3)rpsC b3314 JW3276P0A7V33
30S ribosomal protein S4 (Small ribosomal subunit protein uS4)rpsD ramA b3296 JW3258P0A7V83
30S ribosomal protein S5rpsE spr0206P665823
30S ribosomal protein S5rpsE PP_0471Q88QL83
30S ribosomal protein S5rpsE Z4673 ECs4168P0A7W33
30S ribosomal protein S5 (Small ribosomal subunit protein uS5)rpsE spc b3303 JW3265P0A7W13
30S ribosomal protein S7rpsG spr0249Q8CWU63
30S ribosomal protein S7rpsG PP_0450Q88QN93
30S ribosomal protein S7rpsG Smlt0902B2FQ413
30S ribosomal protein S7rpsG Z4699 ECs4192P666073
30S ribosomal protein S7 (Small ribosomal subunit protein uS7)rpsG b3341 JW3303P023593
30S ribosomal protein S8rpsH CKO_04720A8AQK23
30S ribosomal protein S9rpsI PP_1316Q88N963
30S ribosomal protein S9 (Small ribosomal subunit protein uS9)rpsI b3230 JW3199P0A7X33
4-aminobutyrate aminotransferase (EC 2.6.1.19) (4-aminobutyrate aminotransferase, PLP-dependent) (4-aminobutyrate transaminase) (Aspartate aminotransferase family protein)gabT A5958_16725 AMK83_09480 BW690_12955 ERS085379_00716 PGD_04441 UN86_27190 WQ89_14995 WR15_13220A0A024LBI43
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (EC 1.17.7.3) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase)ispG PA3803Q9HXJ43
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (EC 1.17.7.3) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase)ispG EcE24377A_2799A7ZPV83
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (EC 1.17.7.3) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase)ispG EcHS_A2666A8A3213
4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.7.4)ispH EcE24377A_0029A7ZHB83
4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8)dapB Ec53638_1339A0A0E1T6623
4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8)dapB A4T40_03485 BK334_15735 ECONIH1_00175 MS6198_00380A0A0A1A0J33
5-keto-4-deoxy-D-glucarate aldolase (KDGluc aldolase) (KDGlucA) (EC 4.1.2.20) (2-dehydro-3-deoxy-D-glucarate aldolase) (2-keto-3-deoxy-D-glucarate aldolase) (5-dehydro-4-deoxy-D-glucarate aldolase) (Alpha-keto-beta-deoxy-D-glucarate aldolase)garL BY96_08840A0A027U0913
50 kDa outer membrane proteinomp50 Cj1170cQ0P9863
50S ribosomal protein L1rplA PP_0444Q88QP43
50S ribosomal protein L1rplA Smlt0895B2FQ353
50S ribosomal protein L1rplA Z5557 ECs4907P0A7L23
50S ribosomal protein L1 (Large ribosomal subunit protein uL1)rplA b3984 JW3947P0A7L03
50S ribosomal protein L10rplJ PP_0445Q88QP33
50S ribosomal protein L10rplJ Z5558 ECs4908P0A7J53
50S ribosomal protein L10 (50S ribosomal protein L8) (Large ribosomal subunit protein uL10)rplJ b3985 JW3948P0A7J33
50S ribosomal protein L11rplK Smlt0894B2FQ343
50S ribosomal protein L11rplK EcE24377A_4523A7ZUJ63
50S ribosomal protein L13rplM Smlt4302B2FJU43
50S ribosomal protein L13 (Large ribosomal subunit protein uL13)rplM b3231 JW3200P0AA103
50S ribosomal protein L14rplN PP_0464Q88QM53
50S ribosomal protein L14rplN EcE24377A_3793A7ZSJ93
50S ribosomal protein L15rplO PP_0473Q88QL63
50S ribosomal protein L16rplP PP_0461Q88QM83
50S ribosomal protein L16rplP Smlt0913B2FQ523
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