EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Putative lipoproteinMXAN_7332Q1CVX83
Putative lipoproteinMXAN_7199Q1CWB13
Putative lipoproteinMXAN_7089Q1CWM13
Putative lipoproteinMXAN_7039Q1CWS13
Putative lipoproteinMXAN_7023Q1CWT73
Putative lipoproteinMXAN_6720Q1CXN63
Putative lipoproteinMXAN_6709Q1CXP73
Putative lipoproteinMXAN_6658Q1CXU83
Putative lipoproteinMXAN_6367Q1CYN23
Putative lipoproteinMXAN_5297Q1D1M53
Putative lipoproteinMXAN_3971Q1D5C23
Putative lipoproteinMXAN_2710Q1D8U63
Putative lipoproteinMXAN_2423Q1D9N03
Putative lipoproteinMXAN_1342Q1DCM43
Putative lipoproteinMXAN_0793Q1DE673
Putative lipoproteinMXAN_0522Q1DEY23
Putative lipoproteinCj0089Q0PC483
Putative lipoproteinCj0396cQ0PBB43
Putative lipoproteinCj0406cQ0PBA43
Putative LipoproteinPP_1322Q88N903
Putative LipoproteinPP_0753Q88PU53
Putative LipoproteinPP_5304Q88C793
Putative LipoproteinPP_2121Q88L163
Putative lipoproteinPP_1325Q88N873
Putative LipoproteinPP_4920Q88DA73
Putative LipoproteinPP_1238Q88NH13
Putative LipoproteinPP_1204Q88NK33
Putative LipoproteinPP_0576Q88QB83
Putative LipoproteinPP_1970Q88LG33
Putative lipoprotein MlpAMXAN_1451Q1DCB53
Putative Long-chain fatty acid transporterPP_1689Q88M853
Putative Major tail proteinPP_1573Q88MJ83
Putative MCP-type signal transduction proteinCj0448cQ0PB653
Putative MCP-type signal transduction proteinCj1110cQ0P9E43
Putative MCP-type signal transduction proteinCj1506cQ0P8B23
Putative membrane proteinMXAN_4134Q1D4W43
Putative Membrane-bound lytic murein transglycosylasePP_4798Q88DM73
Putative membrane-bound lytic murein transglycosylase d (EC 3.2.1.-)mltD Smlt3434B2FP063
Putative methyl-accepting chemotaxis signal transduction proteinCj1564Q0P8643
Putative methyltransferaseCj1420cQ0P8J43
Putative murein hydrolase (EC 3.2.1.-)mltB Smlt4052B2FUT43
Putative N-acetylmuramoyl-L-alanine amidaseMXAN_2814Q1D8J23
Putative orn/arg/lys decarboxylaseSmlt2942B2FIM33
Putative outer membrane antigen proteinSmlt3210B2FLE43
Putative Outer membrane ferric siderophore receptorPP_3155Q88I463
Putative Outer membrane ferric siderophore receptorPP_3325Q88HM83
Putative Outer membrane siderophore receptorPP_4137Q88FF93
Putative outer membrane usher protein mrkcmrkC Smlt0708B2FNJ23
Putative oxidoreductaseydjA ECED1_1966B7MVP33
Putative patatin-like phospholipaseSmlt0080B2FU403
Putative penicillin-binding protein (EC 3.4.16.4)dacC Smlt4050B2FUT23
Putative PEPTIDASESmlt4064B2FUU53
Putative peptidyl-prolyl cis-trans isomerase Cbf2 (PPIase Cbf2) (EC 5.2.1.8) (Cell-binding factor 2) (Major antigen peb4A) (Rotamase Cbf2)cbf2 peb4A Cj0596Q0PAS13
Putative periplasmic proteinCj0092Q0PC453
Putative periplasmic proteinCj0114Q0PC233
Putative periplasmic proteinCj0998cQ0P9Q43
Putative phage tail componentECSE_1649B6IAW23
Putative phosphate ABC transporter, periplasmic phosphate-binding proteinPP_5329Q88C543
Putative phosphate acetyltransferase PtaNMB0631Q9K0H13
Putative phosphate selective porinSmlt3950B2FTU33
Putative phosphodiesterase-nucleotide pyrophosphataseSmlt1449B2FHJ53
Putative phytaseMXAN_5326Q1D1J73
Putative secreted proteaseCj0511Q0PB043
Putative Soluble lytic transglycosylasePP_2130Q88L073
Putative surface adhesion proteinPP_0168Q88RG23
Putative Surface adhesion proteinPP_0806Q88PP23
Putative thioredoxin-family proteinCE10_A17A0A0E0VEA73
Putative tonB dependent receptorMXAN_4559Q1D3P63
Putative TonB dependent receptorSmlt2566B2FST23
Putative TonB dependent receptorSmlt3725B2FRP83
Putative TonB dependent receptorSmlt3740B2FRR13
Putative TonB dependent receptorSmlt3905B2FT663
Putative TonB dependent receptorSmlt3645B2FR083
Putative TonB dependent receptor proteinSmlt3446B2FP173
Putative TonB-dependent outer membrane receptor proteinSmlt4026B2FUR13
Putative TonB-dependent outer membrane receptor proteinSmlt2179B2FPN53
Putative TonB-dependent receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acidfhuE Smlt3999B2FUN93
Putative translation-related proteinyhiI PP_5206Q88CH53
Putative Type 1 pili subunit CsuA/B proteinPP_2359Q88KD13
Putative uncharacterized protein (TetR family transcriptional regulator)BE932_13115 SY51_16760Q6KD523
Putative zinc ABC transporterPP_0120Q88RK93
Putrescine aminotransferasespuC PA0299Q9I6J23
Putrescine aminotransferase (EC 2.6.1.82) (Putrescine--2-oxoglutaric acid transaminase) (PAT) (PATase)patA EC3234A_52c00130 EL75_0612 EL79_0634 EL80_0627 HMPREF3040_02069 PGD_04038A0A024L9J03
Putrescine-binding periplasmic proteinpotD-2 NMB0623Q9K0H83
Putrescine-binding periplasmic protein (Spermidine/putrescine ABC transporter substrate-binding protein)potF_1 A4T40_11645 ECONIH1_08370 MS6198_16270A0A0A1A9W03
Pyocin S5pyoS5 PA0985Q9I4Y43
Pyocin-S2 (EC 3.1.-.-) (Killer protein)pys2 PA1150Q065843
Pyridine nucleotide-disulfide oxidoreductaseBY96_26755A0A027TBE43
Pyridoxal 5'-phosphate synthase subunit PdxS (PLP synthase subunit PdxS) (EC 4.3.3.6) (Pdx1) (Superoxide-inducible protein 7) (SOI7)pdxS yaaD BSU00110P375273
Pyridoxine 5'-phosphate synthase (PNP synthase) (EC 2.6.99.2)pdxJ A4T50_06300 BE932_10620 SY51_14685 WM48_13975E2QQ243
Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrase)pcp FTN_0211A0Q4F63
Pyruvate dehydrogenase E1 component (EC 1.2.4.1)aceE FTN_1494A0Q7Z63
Pyruvate dehydrogenase E1 component (EC 1.2.4.1)aceE A4T50_24425 APU18_02290 WM48_00620A0A0D6HYS93
Pyruvate dehydrogenase E1 component (PDH E1 component) (EC 1.2.4.1)aceE b0114 JW0110P0AFG83
Pyruvate dehydrogenase E1 component (PDH E1 component) (EC 1.2.4.1)aceE Z0124 ECs0118P0AFG93
Pyruvate dehydrogenase E1 component subunit beta (EC 1.2.4.1) (S complex, 36 kDa subunit)pdhB aceB BSU14590P218823
Pyruvate kinase (EC 2.7.1.40)pyk FTN_1330A0Q7J03
Pyruvate kinase (EC 2.7.1.40)pykF spr0797Q8DQ843
Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)Cj1476cQ0P8E13
Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)tgt EcE24377A_0436A7ZIF83
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