EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Universal stress protein G (Universal stress protein UspG)uspG A4T40_06655 A4T50_17965 APT94_14090 BE949_14060 BET08_35780 BIQ85_03390 BK248_03155 BK334_18755 BK375_15300 BK383_17835 BUE82_17625 ECONIH1_03495 ERS085406_01680 MS6198_06610 UC41_17640A0A0A1A1D33
Universal stress protein YxiE (USP YxiE)yxiE BSU39250 N17EP422973
UPF0227 protein YcfPycfP BY96_21455A0A027TKW33
UPF0227 protein YcfPycfP BX52_11275A0A0E2U3J63
UPF0234 protein PA4395PA4395Q9HW113
UPF0312 protein PP_4981PP_4981Q88D473
UPF0441 protein YgiBygiB EcE24377A_3501A7ZRR93
Uridine phosphorylase (EC 2.4.2.3)udp A5958_09710 AC789_1c42160 ACN002_3922 ACN81_24000 ACN87_05655 ACU90_13840 AKG99_19900 AM270_17845 AMK83_06870 APT94_08445 ARC77_16115 AU473_01740 BE949_20820 BE957_02925 BE963_10445 BHF46_22425 BHS81_22945 BIQ85_21720 BK251_23025 BK292_00410 BK375_20840 BK383_22425 BMT53_14495 BMT94_14070 BMT97_19840 BN17_37811 BUE82_24450 BV389_09160 BW690_08580 BWP17_23035 BXT93_06390 ECs4761 ERS085379_03153 ERS085383_03379 ERS085386_03446 ERS085404_04442 ERS139235_04545 GJ11_24380 GJ12_23645 HMPREF3040_00243 HW42_00655 PGD_00139 PU06_16990 RG28_24480 SK85_04159 SM09_04814 UC41_14095 UN86_04710 WQ89_13415C3SK473
UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (Alpha-D-glucosyl-1-phosphate uridylyltransferase) (UDP-glucose pyrophosphorylase) (UDPGP) (Uridine diphosphoglucose pyrophosphorylase)galU PA2023Q9I2913
UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)uvrA PA4234Q9HWG03
V-type sodium ATP synthase, subunit ESPCG_0859B2IP403
VacJ like lipoproteinFTN_0322A0Q4R33
VacJ lipoproteinvacJ PP_2163Q88KX63
VgrG1vgrG1 PA0091Q9I7413
Virulence factor MviMBE932_29550 SY51_05905A0A066SX183
Vitamin B12 transporter BtuB (Cobalamin receptor) (Outer membrane cobalamin translocator)btuB bfe cer dcrC b3966 JW3938P061293
Zinc metalloprotease ZmpC (EC 3.4.24.-) (MMP-9 protease)zmpC SP_0071Q97T803
Zinc-binding lipoprotein AdcAadcA spr1975Q8CWN23
(2E,6E)-farnesyl diphosphate synthase (Geranyl transferase)BE932_25720 SY51_02205A0A066T1F62
1,4-dihydroxy-2-naphthoyl-CoA synthase (DHNA-CoA synthase) (EC 4.1.3.36)menB A4T40_16655 BE957_11725 BE963_27125 BK334_03365 BMT94_02775 BMT97_08405 ECONIH1_13215 HMPREF3040_00964 MS6198_25980 SM09_02383A0A023KZH72
1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)dxs ECIAI39_0256B7NJ772
10 kDa chaperonin (GroES protein) (Protein Cpn10)groS groES Smlt4215B2FIV02
10 kDa chaperonin (GroES protein) (Protein Cpn10)groS cpn10 groES BP3496P0A3392
2',3'-cyclic-nucleotide 2'-phosphodiesterase (CpdB)HP_0104O249302
2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16)cpdB NTHI0741Q4QMU22
2':3'-cyclic-nucleotide 2'-phosphodiesterasecpdB SSON_4398Q3YUD42
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) (Tetrahydrodipicolinate N-acetyltransferase) (THP acetyltransferase) (Tetrahydropicolinate acetylase)dapH lmo1011Q8Y8A12
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) (Tetrahydrodipicolinate N-acetyltransferase) (THP acetyltransferase) (Tetrahydropicolinate acetylase)dapH spr1907Q8DN542
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)dapD SSON_0178Q3Z5J22
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)dapD BP1764P0A4U82
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC 5.4.2.11)gpmA gpm BP0607Q7VS432
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (BPG-independent PGAM) (Phosphoglyceromutase) (iPGM) (EC 5.4.2.12)gpmI ACL_0400A9NF912
2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (EC 2.3.1.29) (Glycine acetyltransferase)kbl VSAK1_15142A6D3E02
2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthase) (KDO-8-phosphate synthase) (KDO 8-P synthase) (KDOPS) (Phospho-2-dehydro-3-deoxyoctonate aldolase)kdsA b1215 JW1206P0A7152
2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthase) (KDO-8-phosphate synthase) (KDO 8-P synthase) (KDOPS) (Phospho-2-dehydro-3-deoxyoctonate aldolase)kdsA VSAK1_02114A6D9872
2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthase) (KDO-8-phosphate synthase) (KDO 8-P synthase) (KDOPS) (Phospho-2-dehydro-3-deoxyoctonate aldolase)kdsA BV389_04145 UN91_24010A0A0F3UR242
2-isopropylmalate synthaseleuA FTN_0062A0Q4082
2-methylisocitrate lyase (2-MIC) (MICL) (EC 4.1.3.30) ((2R,3S)-2-methylisocitrate lyase)prpB PA0796Q9I5E22
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquino l hydroxylase (EC 1.14.13.-) (2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase)ubiF yleB A5958_02790 ACN77_23730 ACN81_03070 ACU90_10635 AM270_15675 AMK83_07420 AUS26_05625 BE957_21450 BHS81_03880 BK251_09860 BK292_19445 BMT53_06825 ERS085374_02543 ERS085379_01990 ERS139235_02753 HW42_07160 PU06_25895 RG28_01230 UN86_16665A0A066RHP52
2-octaprenylphenol hydroxylase (Oxidoreductase)BE932_12580 SY51_16325A0A066SVI92
2-oxoglutarate decarboxylase, thiamine-requiring E1 subunit (EC 1.2.4.2)sucA PP_4189Q88FA92
2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylasesucA FTN_1635A0Q8C82
2-oxoisovalerate dehydrogenase complex, E1 component, alpha subunitMXAN_4564Q1D3P12
2-oxoisovalerate dehydrogenase complex, E1 component, beta subunitMXAN_4565Q1D3P02
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD (EC 2.1.1.190) (23S rRNA(m5U1939)-methyltransferase)rlmD rumA ECP_2766Q0TE742
3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12)ribB VSAK1_02604A6CX132
3-dehydroquinate synthase (EC 4.2.3.4)aroB VSAK1_09368A6D7832
3-deoxy-D-manno-octulosonic-acid transferasekdtA FTN_1469A0Q7X22
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ PA3645Q9HXY72
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA) (Beta-hydroxydecanoyl thioester dehydrase) (Trans-2-decenoyl-[acyl-carrier-protein] isomerase) (EC 5.3.3.14)fabA PA1610O338772
3-hydroxyisobutyrate dehydrogenase (HIBADH) (EC 1.1.1.31)mmsB BP1447Q7VYA32
3-hydroxyisobutyrate dehydrogenase, putativeVSAK1_19589A6CWJ82
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)leuC VSAK1_07744A6D7A32
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)leuD VSAK1_07739A6D7A22
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)leuB VSAK1_07749A6D7A42
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)leuB BV389_15080 UN91_11065A0A0F3UIG02
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)leuB BP1483Q7VY732
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Fatty acid oxidation complex subunit beta)fadA VSAK1_12697A6D7Z72
3-oxoacyl-(Acyl-carrier-protein) synthaseVSAK1_10158A6D0N92
3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase)fabG b1093 JW1079P0AEK22
3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase)fabG STM1195P0A2C92
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)fabF FTN_1341A0Q7K12
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)VSAK1_26910A6D7Y02
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)fabF BP2439Q7VW332
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS)aroA BE932_28515 SY51_04890A0A066T4M32
30S ribosomal protein S1rpsA NMB1301Q9JZ442
30S ribosomal protein S1rpsA A3K88_24700 A3L25_17700 AYO08_02010 BIW19_00420 DW66_1702 HB13667_11115 HB4184_18220A0A059UTC62
30S ribosomal protein S1rpsA KPR_3640R4YGT02
30S ribosomal protein S1rpsA Smlt2043B2FNP52
30S ribosomal protein S1rpsA BP0950Q7VZG02
30S ribosomal protein S10rpsJ Cj1708cQ9PLX02
30S ribosomal protein S10rpsJ STM3441P679042
30S ribosomal protein S10rpsJ SSON_3462Q3YWT82
30S ribosomal protein S10rpsJ BP3612Q7VTD42
30S ribosomal protein S10rpsJ LMRG_02177A0A0H3GG092
30S ribosomal protein S10 (Small ribosomal subunit protein uS10)rpsJ nusE b3321 JW3283P0A7R52
30S ribosomal protein S11rpsK STM3417O542962
30S ribosomal protein S11rpsK PP_0477P593742
30S ribosomal protein S11rpsK SSON_3438Q3YWW22
30S ribosomal protein S11 (Small ribosomal subunit protein uS11)rpsK b3297 JW3259P0A7R92
30S ribosomal protein S12rpsL str spr0248P0A4A82
30S ribosomal protein S12rpsL strA STM3448P0A7S62
30S ribosomal protein S12rpsL LMRG_02201A0A0H3GJH52
30S ribosomal protein S12 (Small ribosomal subunit protein uS12)rpsL strA b3342 JW3304P0A7S32
30S ribosomal protein S13rpsM lmo2608P663832
30S ribosomal protein S13rpsM SPy_0077 M5005_Spy0068P663942
30S ribosomal protein S13rpsM SSON_3439Q3YWW12
30S ribosomal protein S13rpsM VSAK1_01734A6D9B32
30S ribosomal protein S13rpsM BP3639Q7VTA82
30S ribosomal protein S13rpsM LMRG_02152A0A0H3GFY02
30S ribosomal protein S13 (Small ribosomal subunit protein uS13)rpsM b3298 JW3260P0A7S92
30S ribosomal protein S14rpsN STM3427P664092
30S ribosomal protein S14rpsN PP_0467 PP0467Q88QM22
30S ribosomal protein S14 (Small ribosomal subunit protein uS14)rpsN b3307 JW3269P0AG592
30S ribosomal protein S15rpsO Cj0884Q0PA132
30S ribosomal protein S15rpsO PP_4709Q88DV92
30S ribosomal protein S15rpsO SSON_3311Q3YX762
30S ribosomal protein S15rpsO VSAK1_10978A6D2432
30S ribosomal protein S15rpsO BP0794Q7VZU12
30S ribosomal protein S15 (Small ribosomal subunit protein uS15)rpsO secC b3165 JW3134P0ADZ42
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