EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Alcohol dehydrogenaseVSAK1_12692A6D7Z62
Alcohol dehydrogenase (Zn-dependent)PA2119Q9I1Z62
Alcohol dehydrogenase, zinc-containingNMB0604Q9K0J32
Aldehyde reductase YahK (EC 1.1.1.2) (Zinc-dependent alcohol dehydrogenase YahK)yahK b0325 JW0317P756912
Aldehyde-alcohol dehydrogenaselmo1634Q8Y6Q02
Aldehyde-alcohol dehydrogenaseACL_0177A9NEM32
Aldehyde-alcohol dehydrogenaseadhE KPR_3118R4YFG82
Aldehyde-alcohol dehydrogenaseadhE SSON_1939Q3Z0V52
Aldehyde-alcohol dehydrogenaseVSAK1_03569A6CXK62
Aldehyde-alcohol dehydrogenase [Includes: Alcohol dehydrogenase (ADH) (EC 1.1.1.1); Acetaldehyde dehydrogenase [acetylating] (ACDH) (EC 1.2.1.10); Pyruvate-formate-lyase deactivase (PFL deactivase)]adhE Z2016 ECs1741P0A9Q82
AlgW proteinalgW PA4446Q9HVX12
Alkyl hydroperoxide reductaseahpC BP3552Q7VTI52
Alkyl hydroperoxide reductase (EC 3.4.-.-)ahpC Cj0334Q0PBH52
Alkyl hydroperoxide reductase AhpD (EC 1.11.1.15)BP0535Q7VSA22
Alkyl hydroperoxide reductase AhpD (EC 1.11.1.15) (Alkylhydroperoxidase AhpD)ahpD BP3551Q7VTI62
Alkyl hydroperoxide reductase subunit C (EC 1.11.1.15) (Alkyl hydroperoxide reductase protein C22) (General stress protein 22) (Peroxiredoxin) (Thioredoxin peroxidase)ahpC BSU40090P802392
Alkyl hydroperoxide reductase, C22 subunitahpC SSON_0557Q3Z4I82
Alpha amylase, catalytic region (EC 3.2.1.1)ACL_0448A9NFD82
Alpha-1,4 glucan phosphorylase (EC 2.4.1.1)glgP ACL_0528A9NFL62
Alpha-1,4 glucan phosphorylase (EC 2.4.1.1)VSAK1_20199A6CWX02
Alpha-1,4 glucan phosphorylase (EC 2.4.1.1)malP PGD_00467A0A024KYG92
Alpha-amylase (EC 3.2.1.1)amyA3 ACL_0657A9NFZ32
Alpha-amylase (EC 3.2.1.1)amyA1 ACL_0667A9NG032
Alpha-D-glucose-1-phosphatase (Alpha-D-glucose-1-phosphate phosphatase YihX) (Glucose-1-phosphatase) (Phosphatase) (EC 3.1.3.-) (Putative phosphatase)yihX A9R57_00970 AKG99_09545 BHS87_21770 BJJ90_25650 BW690_01375 ERS085365_01393 ERS085416_02207 ERS139211_03821 ERS150873_04145 PGD_03092 SK85_04213A0A024L6T32
Alpha-ketoglutarate decarboxylase (EC 1.2.4.2)kgd VSAK1_08948A6D5U22
AmgRamgR PA5200Q9HTY92
Amide hydrolaseVSAK1_25020A6CZ602
Amino acid ABC transporter, periplasmic amino acid-binding proteinVSAK1_16957A6CUV22
Amino acid ABC transporter, periplasmic amino acid-binding proteinVSAK1_00702A6D1A12
Amino acid ABC transporter, periplasmic amino acid-binding proteinVSAK1_05370A6D6H82
Amino acid ABC transporter, periplasmic amino acid-binding proteinVSAK1_00305A6D7S32
Amino acid-binding periplasmic proteinBP0558Q7VS832
Aminoacyl-histidine dipeptidase (Fragment)VSAK1_12130A6D9N82
Aminomethyltransferase (EC 2.1.2.10)VSAK1_22734A6CVV32
Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein)gcvT PA5215Q9HTX52
Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein)gcvT A4T40_19870 APT94_04900 BK334_11180 BK400_16615 BMT49_18105 BMT61_15345 ECONIH1_16725 MJ49_16425 MS6198_32470A0A0A1AHE92
Aminopeptidase (EC 3.4.11.-)pepN spr0706Q8DQF12
Aminopeptidase B (EC 3.4.11.23)VSAK1_12080A6D2Z22
Aminopeptidase NVSAK1_05290A6D6G22
Aminopeptidase T family (EC 3.4.11.-)ampS ACL_0237A9NET32
Aminotransferase (EC 2.6.1.-)FTN_0410A0Q4Z82
Aminotransferase (EC 2.6.1.-)tyrB BP1795Q7VXH52
Aminotransferase, class VVSAK1_13881A6D4912
Anaerobic dimethyl sulfoxide reductase chain A (EC 1.8.99.-)dmsA NTHI1207Q4QLN62
Anaerobic dimethyl sulfoxide reductase chain BdmsB NTHI1206Q4QLN72
Anaerobic nitric oxide reductase flavorubredoxin (FlRd) (FlavoRb)norV flrD ACU57_10610 AM266_17730 EL79_0990 EL80_0993 SK85_02945A0A0A0HE282
Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase)anmK ydhH APU18_09980 BE932_03620 SY51_09160A0A066T0G42
Anthranilate phosphoribosyltransferase (EC 2.4.2.18)trpD spr1635P670002
Anthranilate phosphoribosyltransferase (EC 2.4.2.18)trpD VSAK1_01012A6D5702
Antioxidant protein (EC 3.1.1.-)BP0965Q7VZE72
Antioxidant, AhpC/Tsa family proteinVSAK1_14262A6D7462
Antiterminator proteinlacT spr1072Q8DPP32
Arachidonate 15-lipoxygenase (15-LOX) (EC 1.13.11.33)loxA PA1169Q9I4G82
Arginine ABC transporter, periplasmic arginine-binding proteinVSAK1_21959A6D6S82
Arginine biosynthesis bifunctional protein ArgJ [Cleaved into: Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain] [Includes: Glutamate N-acetyltransferase (EC 2.3.1.35) (Ornithine acetyltransferase) (OATase) (Ornithine transacetylase); Amino-acid acetyltransferase (EC 2.3.1.1) (N-acetylglutamate synthase) (AGSase)]argJ BP3807Q7VSW32
Arginine deiminase (ADI) (EC 3.5.3.6) (Arginine dihydrolase) (AD)arcA VSAK1_02034A6D4E62
Arginine N-succinyltransferase (EC 2.3.1.109)VSAK1_09323A6D7742
Arginine N-succinyltransferase subunit beta (EC 2.3.1.109) (AOST) (AST) (ARUAII)aruG PA0897P803582
Arginine--tRNA ligase (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)argS ACL_0485A9NFH42
Arginine--tRNA ligase (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)argS VSAK1_09028A6D5V82
Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)argG Cj0665cQ9PHK72
Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)argG SFV_3202Q0T0B02
Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)argG VSAK1_09433A6D0C72
Aromatic-amino-acid aminotransferase (EC 2.6.1.57)tyrB BP2858Q7VV462
ArtIartI HPSD74_1263U4SJH82
ArylsulfataseVSAK1_15392A6D7092
Asparagine synthetase BVSAK1_10663A6D1Y02
Asparagine--tRNA ligase (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)asnS ACL_1427A9NE582
Asparagine--tRNA ligase (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)asnC asnS VSAK1_07249A6D4Z72
Aspartate 1-decarboxylase (EC 4.1.1.11) (Aspartate alpha-decarboxylase) [Cleaved into: Aspartate 1-decarboxylase beta chain; Aspartate 1-decarboxylase alpha chain]panD BP1816Q7VXF82
Aspartate aminotransferase (EC 2.6.1.1)VSAK1_14872A6D3862
Aspartate aminotransferase (EC 2.6.1.1)VSAK1_07259A6D4Z92
Aspartate ammonia-lyase (Aspartase) (EC 4.3.1.1)aspA VSAK1_26680A6D8V32
Aspartate--tRNA ligase (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)aspS ACL_0823A9NGF72
Aspartate--tRNA ligase (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)aspS VSAK1_00365A6D7T52
Aspartate--tRNA(Asp/Asn) ligase (EC 6.1.1.23) (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS)aspS FTN_0129A0Q4752
Aspartate--tRNA(Asp/Asn) ligase (EC 6.1.1.23) (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS)aspS BP0709Q7W0012
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase)asd c4220Q8FCR62
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase)asd BP1484P413992
Aspartokinase (EC 2.7.2.4)ask BP1913Q7VX912
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B) (EC 6.3.5.-)gatB lmo1754Q8Y6D32
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B) (EC 6.3.5.-)gatB spr0393Q8DR112
ATP dependent proteaseclpE spr0725Q8DQD72
ATP phosphoribosyltransferase (ATP-PRT) (ATP-PRTase) (EC 2.4.2.17)hisG VSAK1_00185A6D5K02
ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit) (F-ATPase epsilon subunit)atpC Smlt4110B2FHY72
ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit)atpG FTN_1647A0Q8E02
ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit)atpG VSAK1_24600A6D4172
ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit)atpG Smlt4112B2FHY92
ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit)atpG BP3287Q7VU452
ATP synthase subunit a (ATP synthase F0 sector subunit a) (F-ATPase subunit 6)atpB atpA uncB spr1365P0A2Y92
ATP synthase subunit a (ATP synthase F0 sector subunit a) (F-ATPase subunit 6)atpB PP_5419Q88BW82
ATP synthase subunit a (ATP synthase F0 sector subunit a) (F-ATPase subunit 6)atpB VSAK1_24625A6D4222
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)atpA NMB1936Q9JXQ02
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)atpA ACL_0984A9NGW42
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)atpA papA uncA b3734 JW3712P0ABB02
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)atpA VSAK1_24605A6D4182
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)atpA Smlt4113B2FHZ02
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)atpA BP3286Q7VU462
ATP synthase subunit alpha (EC 3.6.3.14) (ATP synthase F1 sector subunit alpha) (F-ATPase subunit alpha)atpA LMRG_02339A0A0H3GCK42
ATP synthase subunit b (ATP synthase F(0) sector subunit b) (ATPase subunit I) (F-type ATPase subunit b) (F-ATPase subunit b)atpF VSAK1_24615A6D4202
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