EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Collagen triple helix repeat proteinMXAN_5295Q1D1M72
Competence proteincglD spr1861Q8DN892
Competence protein ComECLMRG_02600A0A0H3GDJ02
Conjugal transfer protein (Conjugal transfer protein FinO) (Conjugal transfer repressor) (Fertility inhibition protein FinO (Conjugal transfer repressor)) (FinO protein)FinO finO BE932_01565 BE957_01580 ETN48_p0041 IPF_268 pCTXM15_EC8_00045B1VCB52
Conjugative transfer: surface exclusiontraT PSLT103Q93GL92
Conserved ABC-type transport system proteinNTHI1247Q4QLK42
Conserved hypothetical exported proteinSmlt1634B2FJC62
Conserved hypothetical exported proteinSmlt0483B2FKV72
Conserved hypothetical lipoproteinNTHI0363Q4QNT22
Conserved hypothetical lipoproteinNTHI0252Q4QP252
Copper homeostasis protein (Copper homeostasis/adhesion lipoprotein NlpE)BE932_24100 SY51_01085A0A066SSL82
Coproporphyrinogen-III oxidase (EC 1.3.98.3)A4T50_13775 BE932_18710 BK373_19290 BMT49_21660 MJ49_10285 SY51_22050A0A066T9B22
CPS-53 (KpLE1) prophage protein (Phage protein)yfdP_1 yfdP A5958_03605 ACN81_05050 ACU57_00210 ACU57_14065 AUQ13_25380 BE932_11170 BE949_11200 BK373_17610 BK373_27825 BUE81_28320 ERS085366_02776 ERS085379_05401 MJ49_05345 PGD_02153 SM09_01330 UN86_01445A0A024L4V52
Crr proteincrr KPR_1946R4YEV82
CsaA proteincsaA PA3221Q9HZ192
CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)pyrG ctrA BSU37150P132422
CTP synthase (EC 6.3.4.2) (Fragment)VSAK1_08019A6D8H42
Cyanide insensitive terminal oxidasecioA PA3930G3XCW82
Cyanophycin synthetasecphA FTN_1112A0Q6Y32
CyanophycinasecphB FTN_1209A0Q7752
Cyclic AMP receptor proteincrp SSON_3488Q3YWR42
Cyclic AMP receptor-like proteinvfr PA0652P552222
CydA proteincydA KPR_3842R4YI622
Cys/Met metabolism PLP-dependent enzymeMXAN_2035Q1DAQ92
Cysteine desulfurase (EC 2.8.1.7) (Selenocysteine beta-lyase) (SCL) (Selenocysteine lyase) (EC 4.4.1.16) (Selenocysteine reductase)sufS UMNK88_2143A0A0E0TYR62
Cysteine desulfurase IscS (EC 2.8.1.7)iscS VSAK1_12115A6D2Z92
Cysteine peptidase, putativePG_1788Q7MTY92
Cysteine synthase (CSase) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase) (OAS-TL) (O-acetylserine sulfhydrylase)cysK NMB0763Q7DDL52
Cysteine synthase (EC 2.5.1.47)cysKQ8YAC32
Cysteine synthase (EC 2.5.1.47)cysM SPy_1618Q99YN52
Cysteine synthase (EC 2.5.1.47)VSAK1_11435A6D9112
Cytochrome aa3 quinol oxidase subunit ILMRG_02443A0A0H3GGN22
Cytochrome bVSAK1_04840A6D9I12
Cytochrome bd ubiquinol oxidase subunit 1 (EC 1.10.3.-) (Cytochrome d ubiquinol oxidase subunit I)cydA yxkK BSU38760P943642
Cytochrome bd-I terminal oxidase subunit IcydA FTN_0193A0Q4D82
Cytochrome bd-I terminal oxidase subunit IcydA HPSD74_0012U4SPW62
Cytochrome bo terminal oxidase subunit I (EC 1.10.3.10)cyoB PP_0813Q88PN62
Cytochrome cNMB0923Q9JZR92
Cytochrome c oxidase subunit 2 (EC 1.9.3.1)BP3744Q7VT132
Cytochrome c oxidase subunit I, cbb3-type (EC 1.9.3.1)ccoN-I PP_4250Q88F492
Cytochrome c oxidase subunit, cbb3-typeccoO-II PP_4256Q88F432
Cytochrome c oxidase, cbb3-type, CcoN subunitccoN1 PA1554Q9I3G32
Cytochrome c oxidase, subunit CcoNVSAK1_11625A6D6E12
Cytochrome c oxidase, subunit II (EC 1.9.3.1)coxB MXAN_6086Q1CZF22
Cytochrome c-551 (Cytochrome c B) (Cytochrome c551)cccB BSU35270O345942
Cytochrome c-552 (EC 1.7.2.2) (Ammonia-forming cytochrome c nitrite reductase) (Cytochrome c nitrite reductase)nrfA VSAK1_05600A6D5R42
Cytochrome c4NMB1805Q7DD792
Cytochrome c4cc PP_0126Q88RK32
Cytochrome c4 (Fragment)VSAK1_13241A6D9512
Cytochrome c4 (Fragment)VSAK1_13236A6D9T82
Cytochrome c5VSAK1_12793A6D9P72
Cytochrome c551 peroxidaseVSAK1_14590A6D4V32
Cytochrome c554VSAK1_11690A6D8N42
Cytochrome D ubiquinol oxidase subunit I (Cytochrome bd-I ubiquinol oxidase subunit I) (Cytochrome d terminal oxidase polypeptide subunit I)BE932_27315 BE949_13400 BE957_21090 BE963_17870 BV389_04080 BW690_11420 BWP17_20085 BXT93_11905 ECs0768 HMPREF3040_04573C3TIK22
Cytochrome d ubiquinol oxidase subunit IIIVSAK1_04815A6D6C62
Cytochrome d ubiquinol oxidase, subunit IVSAK1_00395A6D7U12
Cytolethal distending toxin BcdtB Cj0078cQ0PC572
Cytolethal distending toxin CcdtC Cj0077cQ0PC582
Cytolethal distending toxin subunit AcdtA HPSD74_0361U4SJD52
Cytolethal distending toxin subunit A (CDT A)cdtA Cj0079cQ0PC562
Cytolethal distending toxin subunit B (EC 3.1.-.-)HPSD74_0360U4SLC82
Cytoskeleton protein RodZrodZ SSON_2598Q3YZ362
Cytotoxicity-associated immunodominant antigen (120 kDa protein) (CAG pathogenicity island protein 26)cagA cag26 cai HP_0547P559802
D-3-phosphoglycerate dehydrogenaseserA FTN_1249A0Q7B52
D-3-phosphoglycerate dehydrogenaseVSAK1_14370A6D9D12
D-alanine--D-alanine ligase (EC 6.3.2.4) (D-Ala-D-Ala ligase) (D-alanylalanine synthetase)ddl BE932_23520 SY51_00525A0A066SSX22
D-alanyl-D-alanine carboxypeptidaseSP70585_0690C1C5Z72
D-alanyl-D-alanine carboxypeptidasedacB SFV_3212Q0T0A22
D-alanyl-D-alanine carboxypeptidase DacA (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Penicillin-binding protein 5) (PBP-5)dacA Z0777 ECs0670P0AEB42
D-alanyl-D-alanine carboxypeptidase/endopeptidase (EC 3.4.16.4)VSAK1_11048A6D8Q02
D-amino acid dehydrogenase (EC 1.4.99.-)dadA KPR_3221R4YB552
D-galactose-binding periplasmic proteinmglB NTHI0987Q4QM782
D-galactose-binding periplasmic proteinmglB HPSD74_0534U4SLZ52
D-galactose-binding periplasmic protein (GBP) (D-galactose/ D-glucose-binding protein) (GGBP)mglB b2150 JW2137P0AEE52
D-galactose-binding periplasmic protein (GBP) (D-galactose/ D-glucose-binding protein) (GGBP)mglB STM2190P239052
D-ribose transporter subunitVSAK1_16167A6CYV12
D12 class N6 adenine-specific DNA methyltransferaseVSAK1_09103A6D7G52
DamX-related proteinVSAK1_09363A6D7822
DctP proteinVSAK1_20294A6CWY92
DctP proteinVSAK1_20684A6CYB42
DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)deaD cshA SPy_1415Q99Z382
Deferrochelatase/peroxidase EfeB (EC 1.11.1.-)efeB SSON_1038Q3Z3962
Degenerate transposase (Orf2)spr0766Q8DQA82
DegP proteindegP KPR_1107R4Y5J42
Dehydrogenase, glucose/sorbosone familyMXAN_6745Q1CXL12
Deleted.0A3M3482
Deleted.0A3M6042
Deleted.0A3M4212
Deleted.0A3M3J32
Deleted.0A3M8X12
Deleted.0A3M8442
Deleted.0A3M7X42
Deleted.0A3M2D72
Deleted.0A3M9B32
Deleted.0A3M7H92
Deleted.0A3M6472
Deleted.0A3M2022
Deleted.0A3MA132
Deleted.0A3M8342
Deleted.0A3M7F82
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