EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Deleted.0A0A0A6SHI02
Deleted.0A0A0F6GU342
Deleted.0A0A0E2A6D52
Deleted.0A0A0A7Y3482
Deleted.0A0A0D6II092
Deleted.0A0A0A7XY082
Deleted.0A0A0E1ZUA12
Delta-aminolevulinic acid dehydratase (EC 4.2.1.24)VSAK1_13205A6D2D02
Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)deoC ACL_0699A9NG352
Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)deoC VSAK1_10848A6D2172
Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)deoC ECS88_5062B7MNI82
DhcA, dehydrocarnitine CoA transferase, subunit AdhcA PA1999Q9I2B02
Di-/tripeptide transporterVSAK1_17912A6CVE32
Diadenylate cyclase (DAC) (EC 2.7.7.85) (Cyclic-di-AMP synthase) (c-di-AMP synthase) (Diadenylate cyclase CdaA)dacA cdaA lmo2120Q8Y5E42
Dienelactone hydrolase and related enzymeVSAK1_16737A6CUQ82
Dienelactone hydrolase family proteinPP_1184Q88NM32
Dihydroaeruginoic acid synthetasepchE PA4226G3XCV22
Dihydrofolate synthase/folylpolyglutamate synthaseBE932_09190 SY51_13220A0A066T8T72
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)pdhCQ8Y8632
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)pdhC ACL_1310A9NHS52
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)LMRG_00516A0A0H3GFB22
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA FTN_1492A0Q7Z42
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)pdhD ACL_1309A9NHS42
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)acoL SPy_1031Q99ZX52
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA KPR_1049R4Y9G62
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA HPSD74_0592U4SM142
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)VSAK1_19664A6CWL32
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)VSAK1_04720A6D6A72
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)odhL Smlt3199B2FLD32
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)odhL BP1126Q7VZ162
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)LMRG_00517A0A0H3GFQ32
Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Glycine cleavage system L protein)lpdA SF0113 S0115P0A9P32
Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate complex) (S complex, 50 kDa subunit)pdhD aceD citL BSU14610P218802
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2) (S complex, 48 kDa subunit)pdhC aceC BSU14600P218832
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB FTN_1634A0Q8C72
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB PP_4188Q88FB02
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)VSAK1_08953A6D5U32
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)odhB BP1125Q7VZ172
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex)sucB Z0881 ECs0752P0AFG72
Dihydroorotase (DHOase) (EC 3.5.2.3)pyrC A9R57_10490 BHS87_05625 BJJ90_15915 ERS085365_03564 ERS085416_00187 ERS139211_03463 ERS150873_02792 WR15_23720W8SRK22
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD VSAK1_24555A6D4082
Dihydroxyacetone kinase, C-terminal domainVSAK1_23579A6CWC22
Dipeptide ABC transporter-periplasmic binding protein (EC 3.6.3.23)dppA-III PP_0885Q88PG52
Dipeptide ABC transporter-periplasmic binding protein (EC 3.6.3.23)dppA-I PP_0882Q88PG82
Disulphide bond formation proteindsbI Cj0017cQ0PCA82
dITP/XTP pyrophosphatase (EC 3.6.1.66) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)PA0387Q9I6A82
DNA binding protein, histone-like proteinACL_0872A9NGK52
DNA gyrase subunit A (EC 5.99.1.3)gyrA FTN_1484A0Q7Y62
DNA gyrase subunit A (EC 5.99.1.3)gyrA spr1099Q8DPM22
DNA gyrase subunit A (EC 5.99.1.3)gyrA ACL_0007A9NE702
DNA gyrase subunit A (EC 5.99.1.3)gyrA PA3168P483722
DNA gyrase subunit A (EC 5.99.1.3)gyrA cafB nalA BSU00070P056532
DNA gyrase subunit B (EC 5.99.1.3)gyrB FTN_0600A0Q5I02
DNA gyrase subunit B (EC 5.99.1.3)gyrBQ8YAV72
DNA gyrase subunit B (EC 5.99.1.3)gyrB PA0004Q9I7C22
DNA gyrase subunit B (EC 5.99.1.3)gyrB VSAK1_12632A6D7Y42
DNA gyrase subunit B (EC 5.99.1.3)gyrB BE932_17745 BHF46_03440 SY51_21115A0A066TB662
DNA helicase (EC 3.6.4.12)PA1372Q9I3X22
DNA ligase (EC 6.5.1.2) (Polydeoxyribonucleotide synthase [NAD(+)])ligA VSAK1_08818A6D8B02
DNA mismatch repair protein HexBhexB spr0160P0A3R22
DNA polymerase III subunit alpha (EC 2.7.7.7)dnaE PA3640Q9HXZ12
DNA polymerase III subunit delta (EC 2.7.7.7)HPSD74_1577U4SGJ12
DNA primase (EC 2.7.7.-)dnaG BE932_14240 SY51_17775A0A061KMV62
DNA protection during starvation protein (EC 1.16.-.-)dps pexB vtm b0812 JW0797P0ABT22
DNA protection during starvation protein (EC 1.16.-.-)dps HPSD74_0868U4SKZ72
DNA protection during starvation protein (EC 1.16.-.-)dps Z1034 ECs0890P0ABT32
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)topA SPy_1164Q99ZM42
DNA topoisomerase 4 subunit A (EC 5.99.1.3) (Topoisomerase IV subunit A)parCQ8Y7J02
DNA topoisomerase 4 subunit A (EC 5.99.1.3) (Topoisomerase IV subunit A)parC spr0757Q8DQB42
DNA topoisomerase 4 subunit A (EC 5.99.1.3) (Topoisomerase IV subunit A)parC PA4964Q9HUK12
DNA topoisomerase 4 subunit A (EC 5.99.1.3) (Topoisomerase IV subunit A)parC BE932_13945 SY51_17485A0A066SXB42
DNA topoisomerase 4 subunit B (EC 5.99.1.3) (Topoisomerase IV subunit B)parEQ8Y7J12
DNA topoisomerase I (EC 5.99.1.2)VSAK1_04022A6D7I92
DNA translocase FtsKftsK ftsQ Cj0886cQ0PA122
DNA-binding proteinVSAK1_00175A6D5J82
DNA-binding protein Bph2bph2 BP2047Q7VWY42
DNA-binding protein HU (HCj)hup hupB Cj0913cQ461212
DNA-binding protein HU-alphahupA PA5348Q9HTL02
DNA-binding protein HU-betaVSAK1_02434A6D9K22
DNA-binding protein Hu-betahupB BP3530Q79GE72
DNA-binding protein HU-beta (HU-1) (NS1)hupB STM0451P0A1R82
DNA-binding response regulator (Transcriptional regulator) (Transcriptional regulatory protein CpxR) (Two-component system response regulator)cpxR A4T50_14005 BE932_18970 BK373_19055 BMT49_21420 ERS085406_03945 MJ49_10050 SY51_22295A0A061YIR22
DNA-binding response regulator in two-component regulatory system with ArcB or CpxAVSAK1_14002A6D3M62
DNA-binding response regulator PhoBVSAK1_14187A6D7312
DNA-binding response regulator PhoBVSAK1_14192A6D7322
DNA-binding transcriptional activatorVSAK1_19199A6CY172
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)rpoA pez phs sez b3295 JW3257P0A7Z42
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)rpoA Cj1595Q9PM802
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)rpoA ACL_0114A9NEG02
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)rpoA PP_0479Q88QL12
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)rpoA BP3642P0A4E52
DNA-directed RNA polymerase subunit alpha 1 (RNAP subunit alpha 1) (EC 2.7.7.6) (RNA polymerase subunit alpha 1) (Transcriptase subunit alpha 1)rpoA1 FTN_0264A0Q4K82
DNA-directed RNA polymerase subunit alpha 2 (RNAP subunit alpha 2) (EC 2.7.7.6) (RNA polymerase subunit alpha 2) (Transcriptase subunit alpha 2)rpoA2 FTN_1412A0Q7R62
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB Cj0478Q461242
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB crsE rfm BSU01070P378702
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB PP_0447Q88QP22
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB KPR_0300R4Y4902
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB SSON_4160Q3YUZ72
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB VSAK1_09853A6D0L12
DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta')rpoC Cj0479Q9PI302
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