| ATP-dependent nuclease (AddB) | HP_0275 | O25052 | 6 |
| Autotransporter | SY51_16805 | A0A0C5ENV9 | 6 |
| Bifunctional protein FolD [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] | folD G925_00505 | A0A0E2LNZ8 | 6 |
| Branched chain amino acid aminotransferase (Branched-chain amino acid aminotransferase) (Branched-chain amino-acid aminotransferase) (EC 2.6.1.42) | ilvE A5958_10045 AMK83_07205 BMT91_24130 ERS085379_03228 PU06_17310 UN86_04375 | A0A066RE28 | 6 |
| Branched-chain-amino-acid aminotransferase (BCAT) (EC 2.6.1.42) (Transaminase B) | ilvE Z5281 ECs4704 | P0AB82 | 6 |
| Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) (Carbamoyl-phosphate synthetase glutamine chain) | carA UTI89_C0036 | Q1RGG8 | 6 |
| Carboxy-S-adenosyl-L-methionine synthase (Cx-SAM synthase) (EC 2.1.3.-) | cmoA EcE24377A_2101 | A7ZMZ5 | 6 |
| Cbb3-type cytochrome c oxidase subunit | ccoP2 PA1555 | Q9I3G2 | 6 |
| Cell division protein ZapA (Z ring-associated protein ZapA) | zapA | Q1JQN5 | 6 |
| Cellulose biosynthesis protein BcsC (Cellulose synthase) | BE932_16705 SY51_20165 | A0A061KCQ7 | 6 |
| Chaperone protein ClpB | clpB PA4542 | Q9HVN5 | 6 |
| Chaperone protein HscA (Hsc66) | hscA CE10_2957 | A0A0E0V815 | 6 |
| Chaperone protein HtpG (Heat shock protein HtpG) (High temperature protein G) | htpG A5958_03930 AMK83_09250 AML07_05780 APZ14_17125 AUS26_03260 ERS085379_01130 ERS150876_00652 FORC28_4608 RG28_02460 UN86_09330 | A0A0F3TBT1 | 6 |
| Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA) | surA Z0062 ECs0058 | P0ABZ8 | 6 |
| Cis-aconitate porin OpdH | opdH PA0755 | Q9I5H4 | 6 |
| Citrate synthase | gltA A4T40_07205 BE932_27230 BK248_02620 BK334_19305 ECONIH1_04050 MS6198_07720 SY51_03655 | A0A061KSA4 | 6 |
| Conserved hypothetical secreted protein | HP_1117 | O25742 | 6 |
| D-3-phosphoglycerate dehydrogenase | serA PA0316 | Q9I6H5 | 6 |
| D-erythro-7,8-dihydroneopterin triphosphate epimerase (Dihydroneopterin triphosphate 2'-epimerase) | folX BE932_09125 SY51_13165 | A0A061YEK6 | 6 |
| D-ribose pyranase (EC 5.4.99.62) | rbsD BE932_18000 SY51_21370 | A0A061YD85 | 6 |
| Deleted. | 0 | A0A0D8VZW7 | 6 |
| Deleted. | 0 | A0A0F4HL10 | 6 |
| Deleted. | 0 | A0A0A7XUV7 | 6 |
| Deleted. | 0 | A0A075L3Q2 | 6 |
| Deleted. | 0 | A0A099AWG5 | 6 |
| Deleted. | 0 | A0A0B0VCE8 | 6 |
| Deleted. | 0 | A0A0E3KPE2 | 6 |
| Deleted. | 0 | A0A0B0XUI7 | 6 |
| Deleted. | 0 | B3HDE5 | 6 |
| Deleted. | 0 | A0A0B1FC31 | 6 |
| Deoxyribose mutarotase (Putative cytoplasmic protein) | EC958_4771 UG58_25720 | W9A105 | 6 |
| Dihydroneopterin aldolase (DHNA) (EC 4.1.2.25) (7,8-dihydroneopterin 2'-epimerase) (7,8-dihydroneopterin aldolase) (7,8-dihydroneopterin epimerase) (EC 5.1.99.8) (Dihydroneopterin epimerase) | folB c3808 | P0AC17 | 6 |
| DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) | topA A4T50_22725 BE932_02210 SY51_07835 | E2QLN3 | 6 |
| DNA-binding protein Fis | fis CKO_04673 | A8AQG0 | 6 |
| DNA-binding protein HU-beta | SD1617_3517 | E2XC85 | 6 |
| DNA-binding protein YbiB (Glycosyl transferase) (Putative glycosyl transferase) (EC 2.4.2.18) | trpD2 BE932_27665 BK373_21910 ERS085406_04367 MJ49_02155 SY51_04095 WM48_04135 | A0A066SYG1 | 6 |
| DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta') | rpoC Ecok1_39560 APECO1_2485 | A1AIG0 | 6 |
| Elastase (EC 3.4.24.26) (Neutral metalloproteinase) (PAE) (Pseudolysin) [Cleaved into: Pro-elastase] | lasB PA3724 | P14756 | 6 |
| Electron transfer flavoprotein subunit beta (Beta-ETF) (Electron transfer flavoprotein small subunit) (ETFSS) | etfB PA2952 | Q9HZP6 | 6 |
| Elongation factor G (EF-G) | fusA EcE24377A_3809 | A7ZSL5 | 6 |
| Elongation factor Tu (EF-Tu) | tuf tufA HP_1205 | P56003 | 6 |
| Ferric uptake regulation protein (Ferric uptake regulator) | fur PA4764 | Q03456 | 6 |
| Fimbrial protein (Putative fimbrial-like exported adhesin protein) | ydeQ PGD_01763 WR15_17885 | A0A024L228 | 6 |
| FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (FKBP22) (PPIase) (EC 5.2.1.8) (Rotamase) | fklB ytfC b4207 JW5746 | P0A9L3 | 6 |
| Flagellin | fliC | Q83XM5 | 6 |
| Flavodoxin 1 | fldA Z0832 ECs0715 | P61951 | 6 |
| Fructosamine kinase | EcSMS35_1466 | B1LE06 | 6 |
| Fructose-bisphosphate aldolase (EC 4.1.2.13) | BX52_23605 | A0A0E2TRQ1 | 6 |
| Fumarate hydratase class I (EC 4.2.1.2) | BE932_20310 SY51_23745 | A0A066SU96 | 6 |
| Fumarate reductase flavoprotein subunit (EC 1.3.5.4) | frdA A4T50_15530 APU18_25400 BE932_21250 ERS085406_00123 SY51_23960 WM48_23085 | E2QK93 | 6 |
| Fumarylacetoacetase | fahA PA2008 | Q9I2A2 | 6 |
| Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase) | proA PA4007 | Q9HX20 | 6 |
| Glucans biosynthesis protein D | mdoD opgD Ecok1_13780 APECO1_572 | A1AB32 | 6 |
| Glucosamine-6-phosphate deaminase (EC 3.5.99.6) (GlcN6P deaminase) (GNPDA) (Glucosamine-6-phosphate isomerase) | nagB A5958_02730 UN86_16605 | A0A0F3S9R5 | 6 |
| Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) | gltX Ecok1_23180 APECO1_4141 | A1ADS2 | 6 |
| Glutaredoxin | grxD EC1303_c17770 | A0A0E1LXK3 | 6 |
| Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) | gpsA EcE24377A_4112 | A7ZTG2 | 6 |
| Glycine betaine ABC transporter substrate-binding protein (Glycine/betaine ABC transporter substrate-binding protein) | proX BE932_11320 SY51_15070 | A0A061YDR4 | 6 |
| Glycine--tRNA ligase beta subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase beta subunit) (GlyRS) | glyS E2348C_3810 | B7ULB9 | 6 |
| GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) | guaA E2348C_2782 | B7UGU5 | 6 |
| GntR family transcriptional regulator | BE932_27185 SY51_03610 | A0A066T289 | 6 |
| GTP binding protein TypA | TTRE_0000705401 | A0A077ZG10 | 6 |
| Heat shock protein hslJ (Heat-inducible protein) (Heat-shock protein HslJ) | hslJ ACU90_19575 AML07_18015 APZ14_18450 AUS26_06690 BHS81_09520 ERS085374_00570 ERS150876_04119 FORC28_3351 HW42_11255 WR15_00345 | A0A066QKG1 | 6 |
| Heme/hemoglobin uptake outer membrane receptor PhuR | phuR PA4710 | Q9HV88 | 6 |
| Hemin TonB-dependent receptor (Hemin receptor) (Ligand-gated channel protein) | chuA hemR A4T40_23220 APU18_01015 BE932_16525 BK334_07060 BMT49_23970 ECONIH1_20415 ERS085406_01747 MS6198_40110 SY51_19995 | A0A023L3G7 | 6 |
| Histidine/lysine/arginine/ornithine transporter subunit periplasmic-binding component of ABC superfamily | hisJ ECUMN_2649 | B7N5S1 | 6 |
| HTH-type transcriptional regulator GntR | gntR PGD_00447 | A0A024KYE6 | 6 |
| Inhibitor of g-type lysozyme (Protein YcgK) | pliG ACU90_08590 AML07_17425 APZ14_02400 AUS26_13135 BMT91_17535 ERS085386_04996 ERS150876_02312 FORC28_2862 | A0A061KE35 | 6 |
| Integration host factor subunit beta (IHF-beta) | ihfB himD UMNK88_1064 | A0A0E0TX53 | 6 |
| Iron-regulated outer membrane protein (FrpB) | HP_1512 | O26042 | 6 |
| Iron-regulated protein (TonB-dependent colicin J protein CjrA) | cjrA A4T50_27085 pEC14_26 | C8CGJ0 | 6 |
| Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS) | ileS ECED1_0023 | B7MNN1 | 6 |
| L,D-transpeptidase (L,D-transpeptidase linking Lpp to murein) (Protein erfK/srfK) | erfK ldtA ACN87_02630 BUE81_28150 EC3234A_99c00020 PGD_01249 | A0A024L0L7 | 6 |
| L-arabinose-binding periplasmic protein (ABP) | A4T50_02025 APU18_08630 WM48_09780 | A0A0D8VZ65 | 6 |
| Lipopolysaccharide 1,3-galactosyltransferase (UDP-D-galactose:(Glucosyl)lipopolysaccharide-alpha-1,3-D-galactosyltransferase) | waaI BE932_17325 SY51_20690 | I7A075 | 6 |
| Lipoprotein | BE932_26470 SY51_02920 | A0A061YEH2 | 6 |
| Long-chain-fatty-acid--CoA ligase | fadD1 PA3299 | Q9HYU4 | 6 |
| LPS-assembly lipoprotein LptE | lptE BY96_24110 | A0A027TFL8 | 6 |
| Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) | lysS ACN81_06240 ACU57_10060 ACU90_05230 BHF46_15555 GJ12_25245 HW42_02295 RG28_26080 | A0A061K9L0 | 6 |
| Malonic semialdehyde reductase (NAD(P)-dependent oxidoreductase) (NADP-dependent 3-hydroxy acid dehydrogenase) (NADP-dependent L-serine/L-allo-threonine dehydrogenase) (EC 1.1.1.-) (Serine 3-dehydrogenase) | ydfG A4T50_00300 AKG99_26725 AM270_16760 AML35_10725 BHF46_11575 BV389_18400 ERS085386_04269 GJ11_10515 HMPREF3040_01414 UN91_26125 | A0A066R614 | 6 |
| Mannonate dehydratase (EC 4.2.1.8) (D-mannonate hydro-lyase) | uxuA UN91_07445 | A0A0F3UNC5 | 6 |
| Membrane protein (Outer membrane lipoprotein) (Outer membrane lipoprotein (Lipocalin)) (Outer membrane lipoprotein Blc) (Outer membrane lipoprotein blc) | blc_1 blc A4T50_15505 AC067_05545 AC789_1c45650 ACN002_4380 ACN81_01660 ACN87_07270 ACU57_19255 ACU90_12870 AKG99_18235 APU18_25375 AWP75_27390 BE932_21225 BE963_12270 BHS81_24870 BK251_24490 BK292_24755 BK337_15595 BK373_03400 BMT49_19220 BMT97_20855 BN17_41311 BW690_00455 BXT93_23630 ERS085366_02358 ERS085374_04938 ERS139235_04272 GJ11_26070 HMPREF3040_03040 JD73_27660 MJ49_08225 PGD_03333 SY51_23935 WQ89_21815 | E2QK88 | 6 |
| Membrane protein (Protein YebE) | BE932_04730 SY51_10235 | A0A061YEQ4 | 6 |
| Membrane-bound lytic murein transglycosylase C (EC 4.2.2.n1) (Murein lyase C) | mltC UMNK88_3661 | A0A0E0U2X6 | 6 |
| Metalloprotease | BE932_12780 SY51_16485 | A0A066SVL3 | 6 |
| Multicopper oxidase | BE932_23720 SY51_00720 | A0A061YEC3 | 6 |
| Murein hydrolase B (EC 3.2.1.-) (EC 4.2.2.-) (Murein hydrolase effector LrgB) (Murein transglycosylase B) | mltB BE932_11445 ERS085411_03320 SY51_15200 | A0A066SV86 | 6 |
| N utilization substance protein B homolog (Protein NusB) | nusB EcE24377A_0447 | A7ZIG9 | 6 |
| N-acetylneuraminate epimerase (EC 5.1.3.24) (N-acetylneuraminate mutarotase) (Neu5Ac mutarotase) (Sialic acid epimerase) | yjhT nanM BE932_22475 BK334_20810 ERS085383_04278 ERS085404_04352 SK85_04656 SY51_24810 | A0A066SPX8 | 6 |
| N-succinylglutamate 5-semialdehyde dehydrogenase (EC 1.2.1.71) (Succinylglutamic semialdehyde dehydrogenase) (SGSD) | astD BE932_04185 SY51_09705 | A0A066T0N7 | 6 |
| Na(+)-translocating NADH-quinone reductase subunit A (Na(+)-NQR subunit A) (Na(+)-translocating NQR subunit A) (EC 1.6.5.8) (NQR complex subunit A) (NQR-1 subunit A) | nqrA PA2999 | Q9HZK6 | 6 |
| NAD-dependent malic enzyme (NAD-ME) (EC 1.1.1.38) | maeA E2348C_1613 | B7URL9 | 6 |
| NAD-dependent protein deacylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog) | cobB c1395 | Q8FIM4 | 6 |
| NAD/NADP-dependent betaine aldehyde dehydrogenase (BADH) (EC 1.2.1.8) | betB BE932_25235 SY51_01745 | A0A066SX29 | 6 |
| NADH dehydrogenase | BX23_15210 | A0A028ED46 | 6 |
| NADH-quinone oxidoreductase subunit B (EC 1.6.5.11) (NADH dehydrogenase I subunit B) (NDH-1 subunit B) | nuoB EcE24377A_2580 | A7ZPA1 | 6 |
| NADH-quinone oxidoreductase subunit F (EC 1.6.5.11) | BV389_16150 UN91_13255 | A0A0F3UG83 | 6 |
| Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase) | ndk PA3807 | Q59636 | 6 |
| Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase) | ndk ECS88_2694 | B7MI03 | 6 |
| Nucleoside-specific channel-forming protein tsx | tsx AC789_1c04100 | A0A0D0NGK1 | 6 |