EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Lmo2418 proteinlmo2418Q8Y4L92
Lmo2431 proteinlmo2431Q8Y4K72
Lmo2439 proteinlmo2439Q8Y4J92
Lmo2451 proteinlmo2451Q8Y4I82
Lmo2518 proteinlmo2518Q8Y4D22
Lmo2767 proteinlmo2767Q8Y3R62
Lon protease (EC 3.4.21.53) (ATP-dependent protease La)lon FTN_1055A0Q6S72
Lon protease (EC 3.4.21.53) (ATP-dependent protease La)lon ACL_0536A9NFM42
Lon protease (EC 3.4.21.53) (ATP-dependent protease La)lon PA0779Q9I5F92
Long-chain fatty acid transport proteinVSAK1_03224A6CXD72
Long-chain fatty acid transport proteinVSAK1_03229A6CXD82
Long-chain fatty acid transport protein (Outer membrane FadL protein) (Outer membrane flp protein)fadL STM2391Q8ZNA52
LPS-assembly lipoprotein LptElptE FTN_0871A0Q6942
LPS-assembly lipoprotein LptElptE NMB0707Q9K0A72
LPS-assembly lipoprotein LptElptE AB237_2936A0A0E1Q0G12
LPS-assembly lipoprotein LptElptE rlpB SSON_0595Q3Z4F12
LPS-assembly lipoprotein LptElptE VSAK1_08788A6D9D92
LPS-assembly lipoprotein LptElptE BP2043Q7VWY82
LPS-assembly lipoprotein LptE (Rare lipoprotein B)lptE rlpB b0641 JW0636P0ADC12
LPS-assembly protein LptDlptD MXAN_2708Q1D8U82
LPS-assembly protein LptDlptD KPR_0975R4YBZ42
LPS-assembly protein LptDlptD imp ostA SSON_0062Q3Z5V52
LPS-assembly protein LptDlptD VSAK1_07719A6D7982
LPS-assembly protein LptDlptD imp ostA BP3329Q7VU132
LPS-assembly protein LptD (Organic solvent tolerance protein)lptD imp ostA yabG b0054 JW0053P315542
LuxTVSAK1_22189A6D6P62
Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)lysU lysS FTN_0168A0Q4B32
Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)lysS asuD herC b2890 JW2858P0A8N32
Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)lysS VSAK1_11183A6D8T72
LysM domain proteinJ512_1343A0A009HQA22
LysM domain protein (Peptidoglycan-binding protein) (Peptidoglycan-binding protein LysM) (Putative peptidoglycan-binding protein)ygaU APT94_01330 BE949_27540 BE963_03040 BIQ85_14775 BMT49_16710 ERS085406_03852 HMPREF3040_03238A0A069CIJ32
LysM domain-containing proteinLMRG_01088A0A0H3GIH22
LysozymeBE932_15635 SY51_19145A0A066SUM42
LysR family transcriptional regulator (LysR substrate binding domain protein) (Transcriptional regulator)APT94_24225 AWP75_11545 BE949_07995 BIQ85_12365 BK337_10435 BK375_01895 BMT94_03330 BXT93_06575 HMPREF3040_02913 UC41_19300A0A0D8W8782
Lysyl endopeptidase (EC 3.4.21.50) (Protease IV) (PvdS-regulated endoprotease)prpL PA4175Q9HWK62
M protein type 1emm1 SPy_2018Q99XV02
Macrodomain Ter proteinmatP EcSMS35_2164B1LJ432
Macrodomain Ter proteinmatP EcE24377A_1070A7ZK592
Maf-like protein BP2447BP2447Q7VW252
Maf-like protein YceFmaf yceF UMNK88_1356A0A0E0TXW02
Magnesium ABC transporter ATPaseWR15_06630A0A0B0W2W32
Magnesium transporter MgtEmgtE PA0913Q9I5442
Magnesium-translocating P-type ATPase (EC 3.6.3.2)mgtA EcE24377A_4814A7ZVC32
Magnesium-transporting ATPase, P-type 1 (Mg(2+) transport ATPase, P-type) (EC 3.6.1.-) (EC 3.6.3.2)mgtA ERS085374_03041 PGD_03429A0A024L7W62
Major antigenic peptide PEB2peb2 Cj0778Q0PAB22
Major antigenic peptide PEB3peb3 Cj0289cQ0PBL72
Major cell-binding factor (CBF1) (PEB1)peb1A Cj0921cQ0P9X82
Major exported protein (Secreted protein hcp)hcpA PA0263; hcpB PA1512; hcpC PA5267Q9HI362
Major outer membrane lipoproteinVSAK1_17977A6CVF62
Major outer membrane lipoprotein 1 (Murein-lipoprotein 1)lpp1 lppA STM1377Q7CQN42
Malate dehydrogenase (EC 1.1.1.37)mdh FTN_0980A0Q6K32
Malate dehydrogenase (EC 1.1.1.37)mdh STM3359P250772
Malate dehydrogenase (EC 1.1.1.37)mdh ECs4109C3SRV22
Malate dehydrogenase (EC 1.1.1.37)mdh BP2365Q7VW972
Malate synthase G (EC 2.3.3.9)glcB VSAK1_20844A6CYE62
Malate synthase G (EC 2.3.3.9)glcB BP3680Q7VT712
MalEHPSD74_0260U4SLS32
Maltoporin (Maltose-inducible porin)lamB SSON_4214Q3YUU92
Maltose ABC transporter periplasmic proteinmalE VSAK1_16507A6CUL22
Maltose ABC transporter periplasmic proteinmalE VSAK1_16547A6CUM02
Maltose operon periplasmic proteinmalM molA b4037 JW3997P038412
Maltose/maltodextrin-binding proteinmalX SPy_1306Q99ZB12
Manganese-binding lipoprotein MntAmntA ytgA BSU30770O343852
Manganese/Zinc/Iron chelate uptake transporter family proteinFTN_0183A0Q4C82
Mannose-1-phosphate guanylyltransferaseVSAK1_09613A6D0G32
Mannose-specific PTS system IIAB component manLLMRG_02345A0A0H3GCZ42
Membrane fusion proteinFTN_1276A0Q7E22
Membrane fusion proteinFTN_1692A0Q8I42
Membrane fusion proteinmtrC NMB1716Q9JY662
Membrane proteinVSAK1_04990A6D3212
Membrane proteinAPU18_00435 BK373_06055 BMT49_16040 MJ49_18415 SY51_14395 WM48_13160A0A061YKR02
Membrane protein (Osmotically-inducible protein OsmY) (Putative phospholipid-binding protein)osmY_1 AA102_07885 ACN77_10630 ACU90_11775 AWP75_13885 BE957_06600 BHS81_18990 ERS085374_01886 PU06_20060A0A086U5892
Membrane protein (Outer membrane protein C)ompC SY51_12725C6K7L72
Membrane protein (Protein YdiY) (Putative outer membrane protein, acid-inducible) (Putative uncharacterized protein) (Salt-induced outer membrane protein)ydiY b1722 A4T40_13290 A4T50_01100 A5958_22675 A9R57_03305 AA102_21720 AC789_1c19030 ACN77_27750 ACN81_10640 ACU90_02755 AKG99_11455 AM270_03315 AMK83_18375 AML35_09955 APT94_06520 ARC77_00900 AU473_19520 BE932_04065 BE963_24020 BHF46_17205 BHS81_10580 BHS87_09760 BIQ85_09845 BJJ90_13800 BK248_10015 BK334_14015 BK373_05080 BK375_03755 BK383_05655 BK400_10725 BMT49_11190 BMT61_02055 BMT94_02520 BMT97_01295 BN17_19821 BUE82_10350 BV389_07700 BWP17_18625 ECONIH1_09955 ECs2428 ERS085365_03053 ERS085374_04226 ERS085379_02242 ERS085383_00127 ERS085386_01316 ERS085406_02836 ERS139211_02882 ERS139235_00828 ERS150873_00746 GJ12_11180 HMPREF3040_05209 HW42_12825 JD73_23360 MJ49_22735 MS6198_19470 PU06_10525 RG28_13480 SM09_04350 SY51_09585 UC41_06050 UN86_21650 UN91_27870 WM48_08805 WQ89_08570C3T7N72
Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC)yidC FTN_0073A0Q4192
Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC)yidC PP_0006P0A1402
Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC)yidC VSAK1_24665A6D4302
Membrane protein insertase YidC 1 (Foldase YidC 1) (Membrane integrase YidC 1) (Membrane protein YidC 1)yidC1 SPy_0247 M5005_Spy0208P656312
Membrane protein insertase YidC 2 (Foldase YidC 2) (Membrane integrase YidC 2) (Membrane protein YidC 2)yidC2 SPy_0351 M5005_Spy0295Q9A1C32
Membrane protein required for colicin V productioncvpA PP_1999Q88LD62
Membrane-bound lytic murein transglycosylase A (EC 4.2.2.n1) (Murein hydrolase A)mltA FTN_1286A0Q7F22
Membrane-bound lytic murein transglycosylase A (EC 4.2.2.n1) (Murein hydrolase A)PA1222Q9I4B62
Membrane-bound lytic murein transglycosylase A (EC 4.2.2.n1) (Murein hydrolase A)mltA AC789_1c31350A0A0E1LBP52
Membrane-bound lytic murein transglycosylase BmltB SFV_2804Q0T1C72
Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-)mltB ABSDF1210B0VUW82
Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-)mltB BP0959Q7VZF22
Membrane-bound lytic murein transglycosylase C (EC 4.2.2.n1) (Murein lyase C)mltC STM3112Q8ZM392
Membrane-bound lytic murein transglycosylase D (Fragment)VSAK1_26920A6D9T12
Meso-diaminopimelate D-dehydrogenase (DAPDH) (Meso-DAP dehydrogenase) (EC 1.4.1.16)ACL_0763A9NG992
Metal ABC transporter substrate-binding lipoproteinmtsA SPy_0453 M5005_Spy0368P0A4G42
Metal dependent amidohydrolaseMXAN_0886Q1DDX62
Metal-dependent phosphohydrolase, HD domain proteinACL_0209A9NEQ52
MetallophosphoesteraseMXAN_3577Q1D6F62
Metalloprotease LoiP (EC 3.4.24.-)loiP yggG b2936 JW2903P258942
Methionine import ATP-binding protein MetN (EC 3.6.3.-)metN FTN_1106A0Q6X72
Methionine import ATP-binding protein MetN 2 (EC 3.6.3.-)metN2 lmo2419Q8Y4L82
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG VSAK1_03444A6CXI12
Methyl-accepting chemotaxis protein PctCpctC PA4307O324402
Methyltransferase (EC 2.1.1.-)spnIM spr1287Q8DP912
Methyltransferase, putativeVSAK1_17397A6CV402
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