EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Mid-cell-anchored protein ZmapZ SPy_1643Q99YL62
MlaAHPSD74_2190U4S7Z52
Modulator of FtsH protease HflChflC Z5782 ECs5151P0ABC52
Molecular chaperone, heat shock protein Hsp20ibpA ACL_0421A9NFB22
Molybdate-binding periplasmic proteinmodA b0763 JW0746P373292
Molybdate-binding periplasmic proteinmodA NTHI2000Q4QJP82
Molybdate-binding periplasmic proteinmodA SSON_0715Q3Z4472
Molybdate-binding periplasmic proteinmodB BP3095Q7VUJ32
Molybdenum ABC transporter, periplasmic molybdenum-binding proteinVSAK1_14847A6D3812
Molybdenum cofactor biosynthesis protein BVSAK1_03685A6D3S52
Molybdenum cofactor guanylyltransferase (MoCo guanylyltransferase) (EC 2.7.7.77) (GTP:molybdopterin guanylyltransferase) (Mo-MPT guanylyltransferase) (Molybdopterin guanylyltransferase) (Molybdopterin-guanine dinucleotide synthase) (MGD synthase)mobA APU18_14050 BE932_18650 ERS085406_03888 SY51_22000A0A061Y9B72
MSHA biogenesis protein MshLVSAK1_08206A6D0242
MSHA biogenesis protein MshNVSAK1_08216A6D0262
MSHA pilin protein MshBVSAK1_08236A6D0302
MshA, mannose-sensitive haemaglutininVSAK1_08241A6D0312
Muconate cycloisomerase 1 (EC 5.5.1.1)catB PP_3715Q88GK62
Muconate cycloisomerase IcatB PA2509Q9I0X32
Multidrug efflux outer membrane protein OprNoprN PA2495Q9I0Y72
Multifunctional fusion protein [Includes: Protein translocase subunit SecD; Protein-export membrane protein SecF]secD secF LMRG_01443A0A0H3GH332
Murein hydrolase activator NlpDnlpD b2742 JW2712P0ADA32
Murein hydrolase activator NlpDnlpD STM2925P408272
Murein L,D-transpeptidaseBE932_03825 SY51_09355A0A066SRW02
Murein transglycosylase AmltA VSAK1_08626A6D0A82
N-acetyl-D-glucosamine kinase (EC 2.7.1.59) (GlcNAc kinase)nagK VSAK1_05435A6D5N12
N-acetyl-gamma-glutamyl-phosphate reductase (AGPR) (EC 1.2.1.38) (N-acetyl-glutamate semialdehyde dehydrogenase) (NAGSA dehydrogenase)argC PA0662Q9I5Q92
N-acetyl-gamma-glutamyl-phosphate reductase (AGPR) (EC 1.2.1.38) (N-acetyl-glutamate semialdehyde dehydrogenase) (NAGSA dehydrogenase)argC BP2960Q7VUW02
N-acetylmuramoyl-L-alanine amidaseVSAK1_09978A6D8D62
N-acetylmuramoyl-L-alanine amidaseLMRG_02909A0A0H3GKJ72
N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28)amiC BP0246Q7W0A42
N-acetylmuramoyl-l-alanine amidase IIamiB SSON_4354Q3YUH42
N-succinylglutamate 5-semialdehyde dehydrogenase (EC 1.2.1.71) (Succinylglutamic semialdehyde dehydrogenase) (SGSD)astD VSAK1_09318A6D7732
N5-carboxyaminoimidazole ribonucleotide mutase (N5-CAIR mutase) (EC 5.4.99.18) (5-(carboxyamino)imidazole ribonucleotide mutase)purE PA5426P721572
N5-carboxyaminoimidazole ribonucleotide mutase (N5-CAIR mutase) (EC 5.4.99.18) (5-(carboxyamino)imidazole ribonucleotide mutase)purE BP1526Q7VY372
Na Ca ex and CBS and SIS and Hydrolase 3 domain c ontaining proteinTTRE_0000738401A0A077ZGW22
Na(+)-translocating NADH-quinone reductase subunit A (Na(+)-NQR subunit A) (Na(+)-translocating NQR subunit A) (EC 1.6.5.8) (NQR complex subunit A) (NQR-1 subunit A)nqrA HPSD74_1029U4SHF22
Na(+)-translocating NADH-quinone reductase subunit A (Na(+)-NQR subunit A) (Na(+)-translocating NQR subunit A) (EC 1.6.5.8) (NQR complex subunit A) (NQR-1 subunit A)nqrA VSAK1_12200A6D8722
Na(+)-translocating NADH-quinone reductase subunit B (Na(+)-NQR subunit B) (Na(+)-translocating NQR subunit B) (EC 1.6.5.8) (NQR complex subunit B) (NQR-1 subunit B)nqrB VSAK1_12195A6D8712
Na(+)-translocating NADH-quinone reductase subunit C (EC 1.6.5.-)VSAK1_12185A6D8692
Na(+)-translocating NADH-quinone reductase subunit C (EC 1.6.5.-)VSAK1_12190A6D8702
Na(+)-translocating NADH-quinone reductase subunit D (Na(+)-NQR subunit D) (Na(+)-translocating NQR subunit D) (EC 1.6.5.8) (NQR complex subunit D) (NQR-1 subunit D)nqrD VSAK1_12180A6D8682
Na(+)-translocating NADH-quinone reductase subunit F (Na(+)-NQR subunit F) (Na(+)-translocating NQR subunit F) (EC 1.6.5.8) (NQR complex subunit F) (NQR-1 subunit F)nqrF PA2994Q9HZL12
Na(+)-translocating NADH-quinone reductase subunit F (Na(+)-NQR subunit F) (Na(+)-translocating NQR subunit F) (EC 1.6.5.8) (NQR complex subunit F) (NQR-1 subunit F)nqrF VSAK1_12170A6D8662
Na+-transporting NADH:ubiquinone oxidoreductase subunit C (EC 1.6.5.-)nqrC ACL_0967A9NGU72
NAD dependent epimerase/dehydratase familyMXAN_0533Q1DEX12
NAD nucleotidasenadN NTHI0303Q4QNY42
NAD(P) transhydrogenase subunit alpha (EC 1.6.1.2)pntA VSAK1_14807A6D3732
NAD(P)-dependent oxidoreductase (dTDP-4-dehydrorhamnose reductase) (EC 1.1.1.133)rmlD BE932_07655 BET08_08605 SY51_11835A0A023KZ822
NAD(P)H-dependent FMN reductaseACL_0238A9NET42
NAD-dependent malic enzymemaeA FTN_0443A0Q5312
NAD-dependent oxidoreductaseVSAK1_03319A6CXF62
NAD-specific glutamate dehydrogenase (EC 1.4.1.2)gdhB PP_2080Q88L552
NADH dehydrogenase I, F subunitnuoF FTN_1675A0Q8G72
NADH-quinone oxidoreductase subunit A (EC 1.6.5.11) (NADH dehydrogenase I subunit A) (NDH-1 subunit A) (NUO1)nuoA PP_4119Q88FH72
NADH-quinone oxidoreductase subunit B (EC 1.6.5.11) (NADH dehydrogenase I subunit B) (NDH-1 subunit B)nuoB Smlt3404B2FNX82
NADH-quinone oxidoreductase subunit C (EC 1.6.5.11) (NADH dehydrogenase I subunit C) (NDH-1 subunit C)nuoC FTN_1678A0Q8H02
NADH-quinone oxidoreductase subunit C/D (EC 1.6.5.11) (NADH dehydrogenase I subunit C/D) (NDH-1 subunit C/D) (NUO3/NUO4)nuoC nuoCD nuoD b2286 JW5375P335992
NADH-quinone oxidoreductase subunit I (EC 1.6.5.11) (NADH dehydrogenase I subunit I) (NDH-1 subunit I)nuoI PA2644Q9I0J42
NADH-ubiquinone oxidoreductase, NQO3 subunit (NQO3)HP_1266O258562
NADP-dependent malic enzyme (EC 1.1.1.40)maeB BP1120Q7VZ222
NarG proteinnarG KPR_3132R4YB122
NarH proteinnarH KPR_3131R4YAC32
Neutral zinc metallopeptidase (Putative peptidase) (YpfJ protein, zinc metalloprotease superfamily)A5958_18170 A9R57_16640 AA102_04265 ACN77_08850 ACU90_01075 AM270_06710 AMK83_10930 AML07_10835 APZ14_05910 AUS26_08920 BHS87_14000 BJJ90_06910 BMT53_23350 ERS085365_02850 ERS085374_00122 ERS085379_00991 ERS085416_01325 ERS139211_02636 ERS150873_01474 ERS150876_00773 FORC28_1486 PU06_04995 RG28_09535 UN86_00320A0A066Q6422
NHL repeat proteinMXAN_6584Q1CY182
NifS-related proteinVSAK1_06235A6CZN72
Nitrate reductase (EC 1.7.99.4)napA VSAK1_22399A6CVN62
Nitrate/nitrite response regulator proteinVSAK1_22419A6CVP02
Nitrogen regulatory IIA protein (EC 2.7.1.69)rpoP BP0694Q7W0122
Nitrogen regulatory protein P-II 2glnK PA5288Q9HTR62
NLPA lipoproteinplpB PP_5165Q88CL52
NlpD proteinnlpD KPR_4101R4YHC82
NlpD putative outer membrane lipoproteinnlpD HPSD74_0695U4SKD52
Non-hemolytic phospholipase C (EC 3.1.4.3) (PLC-N) (Phosphatidylcholine cholinephosphohydrolase) (Phosphatidylcholine-hydrolyzing phospholipase C) (PC-PLC)plcN PA3319P157132
Nucleoid-associated protein PA1533PA1533Q9I3I02
Nucleoprotein/polynucleotide-associated enzymeyaiL BE932_25430 BK248_04775 ERS085406_02258 SY51_01920 WM48_02115A0A066SXJ02
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)ndk VSAK1_12075A6D2Z12
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)ndk BP2202Q7VWK72
Nucleoside triphosphate hydrolase (EC 3.6.1.19) (Nucleoside triphosphate pyrophosphohydrolase) (Protein MazG)mazG ACN81_20380 AML35_05295 APT94_17885 BE949_26875 BHF46_05055 BIQ85_15420 BK400_05825 BMT94_18555 BMT97_03130 BV389_24170 HMPREF3040_01162 SM09_02918 UN91_03640A0A023KRU92
Nucleoside-specific channel-forming protein tsxtsx STM0413P0A2612
Nucleoside-specific channel-forming protein Tsxtsx ACIN5021_3855L9LUH12
Nucleoside-specific channel-forming protein tsxtsx Z0512 ECs0464P0A9282
O-succinylhomoserine sulfhydrylase (OSH sulfhydrylase) (OSHS sulfhydrylase) (EC 2.5.1.-)metZ PA3107P552182
Octaprenyl-diphosphate synthaseispB PA4569Q9HVL52
Oligoendopeptidase F (EC 3.4.24.-)pepB2 ACL_1181A9NHF02
Oligoendopeptidase F, M3B family (EC 3.4.24.-)ACL_0119A9NEG52
Oligoendopeptidase, M3 peptidase familyACL_0733A9NG692
Oligopeptide ABC transporter, periplasmic oligopeptide-binding proteinVSAK1_15842A6CYN62
Oligopeptide ABC transporter, periplasmic oligopeptide-binding proteinVSAK1_06595A6D1S72
Oligopeptide ABC transporter, periplasmic oligopeptide-binding proteinVSAK1_22309A6D8A42
Oligopeptide transport ATP-binding protein OppF (Stage 0 sporulation protein KE)oppF spo0KE BSU11470P241372
Oligopeptide-binding protein AliBaliB spr1382P0A4G12
OmpA domain proteinMXAN_6898Q1CX612
OmpA domain proteinMXAN_6246Q1CYZ82
OmpA domain proteinMXAN_4254Q1D4J42
OmpA domain proteinMXAN_2090Q1DAK42
OmpA domain proteinMXAN_5042Q1D2C62
OmpA family proteinMXAN_5152Q1D2182
OmpA family proteinPP_1128Q88NS62
OmpA proteinompA KPR_1669R4YB962
OmpA/MotB domain proteinRPE_1792Q07QP42
OmpC proteinompC KPR_2077R4Y8072
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