EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Outer membrane protein, putativeVSAK1_16667A6CUP42
Outer membrane protein, putativeVSAK1_16672A6CUP52
Outer membrane receptor for ferric enterobactin (Enterochelin) and colicins B and DfepA SSON_0534Q3Z4L02
Outer membrane receptor protein (TonB-dependent siderophore receptor)BE932_26505 SY51_02960A0A061YDS82
Outer membrane usher protein FimCfimC fhaA BP1882P334102
Outer-membrane lipoprotein carrier proteinlolA ABSDF0745B0VSH72
Outer-membrane lipoprotein carrier proteinlolA SSON_0892Q3Z3M92
Outer-membrane lipoprotein carrier proteinlolA VSAK1_00060A6D5H52
Outer-membrane lipoprotein carrier proteinlolA BP2472Q7VW062
Outer-membrane lipoprotein LolBlolB hemM ychC b1209 JW1200P613202
Outer-membrane lipoprotein LolBlolB ABSDF2625B0VTW92
Outer-membrane lipoprotein LolBlolB SSON_1969Q3Z0S72
Outer-membrane lipoprotein LolBlolB BP3127Q7VUG92
Oxaloacetate decarboxylase (EC 4.1.1.3)VSAK1_07794A6D8442
Oxidoreductase FAD/NAD(P)-binding proteinVSAK1_10233A6D0Q42
Oxidoreductase, short-chain dehydrogenase/reductase family proteinVSAK1_20719A6CYC12
p-type ATPase-metal/cation transport (EC 3.6.3.10)ctpC spr1911Q8DN512
PanD regulatory factorpanZ A4T40_22940 BK334_23245 ECONIH1_20145 MS6198_39620A0A0A1ABE32
Pantothenate synthetase (PS) (EC 6.3.2.1) (Pantoate--beta-alanine ligase) (Pantoate-activating enzyme)panC BE932_23780 SY51_00775A0A061KSC82
ParA family proteinVSAK1_24640A6D4252
ParB family proteinVSAK1_19634A6CWK72
PAS:GGDEFVSAK1_15337A6D6532
PbgE1 proteinVSAK1_04192A6D6692
PblBSP70585_0074C1C9R12
PbpA proteinpbpAQ8Y6102
PdhA proteinpdhAQ8Y8652
PdhB proteinPdhBQ8Y8642
PDZ domain proteinPG_1726Q7MU402
Pectinesterase (EC 3.1.1.11)ybhC STM0786Q8ZQR32
Pectinesterase (EC 3.1.1.11)ybhC A4T50_18710 APU18_20740 BE932_27525 BMT97_08175 ERS085406_01530 SY51_03945A0A023KV232
Pectinesterase (EC 3.1.1.11)ybhC ECs0800 Z0943Q8X8912
Penicillin-binding protein 1A (EC 2.4.2.-)mrcA BP0905Q7VZJ72
Penicillin-binding protein 1A (EC 2.4.2.-)BP3655Q7VT952
Penicillin-binding protein 1A (PBP-1A) (Exported protein 2) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.1.129) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]pbpA exp2 spr0329Q8DR592
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)APD06_10835A0A0J8V1R22
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)VSAK1_05075A6D3382
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.1.129) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]mrcB pbpF ponB b0149 JW0145P029192
Penicillin-binding protein 2apbp2A SPy_2059Q99XS52
Penicillin-binding protein 2X (PBP-2X) (PBP2X)pbpX spr0304P596762
Penicillin-binding protein 7pbpG SSON_2191Q3Z0702
Penicillin-binding protein activator LpoA (PBP activator LpoA)yraM lpoA STM3264Q8ZLU42
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA NTHI1957Q4QJT82
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA KPR_4749R4YEQ92
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA SFV_3177Q0T0D42
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA HPSD74_0866U4SK702
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA VSAK1_05150A6D3532
Penicillin-binding protein activator LpoA (PBP activator LpoA)yraM lpoA CE10_3677A0A0E0V9Z92
Penicillin-binding protein activator LpoB (PBP activator LpoB) (Lipoprotein activator of PBP from the outer membrane B)lpoB ycfM b1105 JW5157P0AB382
Peptidase family S49 proteinsohB FTN_0550A0Q5D02
Peptidase M16-like proteinVSAK1_18072A6CVH52
Peptidase T (EC 3.4.11.4)ACL_0998A9NGX82
Peptidase, M13 (Neprilysin) family (EC 3.4.24.-)MXAN_3160Q1D7L02
Peptidase, M16 (Pitrilysin) family (EC 3.4.24.-)MXAN_1624Q1DBU72
Peptidase, M16 (Pitrilysin) family (EC 3.4.24.-)MXAN_1623Q1DBU82
Peptidase, M16 familyPG_0196Q7MXI92
Peptidase, M28E family (EC 3.4.11.-)MXAN_2760Q1D8P62
Peptidase, M48 (Ste24 endopeptidase) family (EC 3.4.-.-)MXAN_5933Q1CZV32
Peptide ABC transporter, periplasmic peptide-binding proteinVSAK1_12840A6D2572
Peptide ABC transporter, periplasmic peptide-binding proteinVSAK1_08084A6D7V52
Peptide ABC transporter, periplasmic peptide-binding protein, putativeVSAK1_23024A6CW112
Peptide chain release factor 2 (RF-2)prfB PA3701P0C3482
Peptide chain release factor 3 (RF-3)prfC PA3903Q9HXB02
Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)msrA FTN_1772A0Q8Q72
Peptide transport periplasmic protein-like proteinsapA SSON_1846Q3Z1422
Peptidoglycan associated lipoprotein (Omp18)pal Cj0113Q0PC242
Peptidoglycan D,D-transpeptidase FtsI (EC 3.4.16.4) (Penicillin-binding protein 3) (PBP-3)ftsI pbpB PA4418G3XD462
Peptidoglycan-associated lipoproteinpal AB237_0813A0A0E1PNB32
Peptidoglycan-associated lipoproteinpal HPSD74_0020U4SP622
Peptidoglycan-associated lipoproteinVSAK1_00445A6D8I32
Peptidoglycan-associated lipoprotein (Peptidoglycan-associated outer membrane lipoprotein)pal A4T50_18565 APU18_20575 BE932_27360 BK373_24450 ERS085406_01561 MJ49_02845 SY51_03780 WM48_03820E2QIB42
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)MXAN_4085Q1D5102
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)PG_2164Q7MT312
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)fkbY NTHI0707Q4QMX12
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)HMPREF0010_03292D0CEW22
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)KPR_0740R4YBB02
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)HPSD74_1634U4SEU82
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (Fragment)VSAK1_01764A6D9V62
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)ppiA PP_4541Q88EC52
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)SPy_0457Q9A1562
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)ppiB PA1793Q9I2U92
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)VSAK1_12220A6D8762
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)ppiB BP1906Q7VX982
Peptidyl-prolyl cis-trans isomerase, FKBP-type (Fragment)VSAK1_09908A6D8C22
Peptidylarginine deiminase (EC 3.5.3.-)PG_1424Q9RQJ22
Peptidylprolyl isomerase (EC 5.2.1.8)PP_2304Q88KI62
Peptidylprolyl isomerase (EC 5.2.1.8)ybaU KPR_4316R4YHL62
Peptidylprolyl isomerase (EC 5.2.1.8)Smlt0993B2FR552
Periplasmic linker protein, putativeVSAK1_07039A6D5552
Periplasmic negative regulator of sigmaErseB VSAK1_07944A6D8F92
Periplasmic nitrate reductase, electron transfer subunit (Diheme cytochrome c NapB)VSAK1_22394A6CVN52
Periplasmic oligopeptide-binding proteinoppA b1243 JW1235P238432
Periplasmic oligopeptide-binding proteinoppA NTHI1292Q4QLH02
Periplasmic protein involved in polysaccharide exportVSAK1_04262A6D6832
Periplasmic serine endoprotease DegP-like (EC 3.4.21.107)degQ SSON_3375Q3YX142
Periplasmic serine endoprotease DegP-like (EC 3.4.21.107)Smlt0381B2FJ522
Periplasmic serine endoprotease DegP-like (EC 3.4.21.107)mucD BP2434Q7VW382
Periplasmic solute-binding proteinBP3674Q7VT772
Periplasmic substrate-binding transport protein, putativeVSAK1_20169A6CWW42
Periplasmic sulfate-binding proteinsbp SSON_4086Q3YV612
PeroxidaseBY96_26490A0A027U5Z62
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