EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein TolAtolA PA0971P506002
Protein TolBtolB STM0748Q8ZQT52
Protein TolBtolB NTHI0502Q4QNG02
Protein TolBtolB F911_01083 HMPREF0010_02143D0CBL32
Protein TolBtolB SSON_0692Q3Z4642
Protein TolBtolB HPSD74_0019U4SMV82
Protein TolBtolB VSAK1_00440A6D8I22
Protein TonBtonB BP3531Q79GE62
Protein translocase subunit SecAsecA FTN_0672A0Q5P92
Protein translocase subunit SecAsecA Cj0942cQ0P9V72
Protein translocase subunit SecAsecA ACL_0330A9NF222
Protein translocase subunit SecAsecA VSAK1_26795A6D9F72
Protein translocase subunit SecAsecA Smlt0764B2FPB22
Protein translocase subunit SecDsecD FTN_1095A0Q6W62
Protein translocase subunit SecDsecD PP_0835Q88PL52
Protein translocase subunit SecDsecD SSON_0385Q3Z5012
Protein translocase subunit SecDsecD Smlt2011B2FN022
Protein translocase subunit SecDsecD E2348C_0343B7UJN12
Protein translocase subunit SecYsecY VSAK1_01724A6D9B12
Protein YceIyceI SSON_1076Q3Z3602
Protein YdgHydgH b1604 JW1596P761772
Protein-disulfide isomeraseVSAK1_22279A6D8982
Protein-disulfide isomeraseVSAK1_11203A6D8U12
Protein-methionine-sulfoxide reductase catalytic subunit MsrP (EC 1.8.5.-)msrP VSAK1_19889A6CWQ82
Protein-methionine-sulfoxide reductase catalytic subunit MsrP (EC 1.8.5.-)msrP BP0479Q7VSE92
Pseudouridine synthase (EC 5.4.99.-)BE932_19620 SY51_23125A0A066SUN42
Pseudouridine synthase (EC 5.4.99.-)rluD BE932_10790 SY51_14845A0A066T1F52
PslBpslB PA2232Q9I1N72
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD)phhB PA0871P433352
PTS glucose-specific enzyme IIABC componentptsG spr0668Q8DQH22
PTS system trehalose-specific EIIBC component (EIIBC-Tre) (EII-Tre) [Includes: Trehalose-specific phosphotransferase enzyme IIB component (EC 2.7.1.201) (PTS system trehalose-specific EIIB component); Trehalose permease IIC component (PTS system trehalose-specific EIIC component)]treP treB BSU07800P397942
Pullulanase, surface-anchored protein (EC 3.2.1.41)ACL_0665A9NG012
Pur operon repressorpurR spr1793P658332
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1)deoD VSAK1_18002A6CVG12
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1)deoD VSAK1_10833A6D2142
Purine-nucleoside phosphorylase (EC 2.4.2.1)deoD ACL_0698A9NG342
Putative 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)sucA Smlt3197B2FLD12
Putative 3-methyladenine DNA glycosylase (EC 3.2.2.-)PA4010Q9HX172
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase (HMG aldolase) (EC 4.1.3.17) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.3) (Regulator of ribonuclease activity homolog) (RraA-like protein)PA1772Q9I2W72
Putative 5'-nucleotidaseMXAN_2236Q1DA662
Putative ABC transport solute-binding proteinBP2747Q7VVC92
Putative ABC transporter (ATP-binding protein)SPy_1316Q99ZA32
Putative ABC transporter (Binding protein)SPy_0903Q9A0742
Putative ABC transporter (Lipoprotein)SPy_0163Q9A1P72
Putative ABC transporter (Substrate-binding protein)SPy_0778Q9A0H22
Putative ABC transporter arginine-binding protein 2artI b0863 JW0847P308592
Putative ABC transporter periplasmic amino acid-binding proteinBP3831Q7VSU12
Putative ABC transporter substrate binding proteinBP0301Q7W0612
Putative ABC transporter substrate-binding lipoprotein YhfQyhfQ BSU10330C0SP942
Putative ABC transporter toluene tolerance exported proteinSmlt4673B2FP852
Putative ABC-type Co2+ transport system, periplasmic componentNTHI1418Q4QL592
Putative acetoin dehydrogenase (TPP-dependent) beta chainacoB SPy_1028Q99ZX72
Putative acetoin utilization protein AcuBVSAK1_14272A6D7482
Putative acid phosphataselppC SPy_1882Q99Y382
Putative adhesinNMB0586Q9K0K82
Putative adhesinyebL SSON_1284Q3Z2L52
Putative aldehyde dehydrogenaseVSAK1_23174A6CW412
Putative aldehyde dehydrogenaseVSAK1_25220A6CZA02
Putative aldehyde dehydrogenaseBP3624Q7VTC22
Putative alkaline phosphataseVSAK1_18504A6CXM82
Putative alkylphosphonate ABC tranporterVSAK1_22349A6CVM62
Putative alpha helix proteinyfhG SSON_2638Q3YZ002
Putative amidaseycbB SFV_0927Q0T6B62
Putative amidaseSSON_2974Q3YY432
Putative amine oxidasePP_4983Q88D452
Putative Amino acid ABC transporter, periplasmic amino acid-binding proteinPP_0657Q88Q412
Putative amino acid ABC transporter, periplasmic amino acid-binding proteinSPy_1274Q99ZD72
Putative amino acid-binding periplasmic proteinBP1532Q7VY312
Putative amino-acid ABC transporter, periplasmic amino acid-binding proteinBP1364Q7VYH52
Putative amino-acid ABC transporter-binding protein YhdWyhdW PP_1297Q88NB52
Putative aminohydrolaseBP3063Q7VUM22
Putative aminopeptidase YhfE (EC 3.4.11.-)yhfE BSU10200O076032
Putative aminopeptidase YsdC (EC 3.4.11.-)ysdC BSU28820P945212
Putative aminotransferase (EC 2.6.1.17)BP2785Q7VVA02
Putative anaerobic ribonucleoside-triphosphate reductase (EC 1.17.4.-)nrdD SPy_2110Q99XP72
Putative ATP-binding cassette transporter-like proteinSPy_2032Q99XU22
Putative ATP-binding component of ABC transporterVSAK1_19509A6CWI22
Putative autotransporterEC958_4121W9AM672
Putative bacterioferritin comigratory proteinBP1307Q7VYL22
Putative beta-barrel assembly-enhancing protease (EC 3.4.-.-)VSAK1_07389A6D3F52
Putative beta-lactamase HcpE (EC 3.5.2.6) (Cysteine-rich protein E)hcpE HP_0235O250212
Putative binding-protein-dependent transport periplasmic proteinBP2396Q7VW702
Putative binding-protein-dependent transport proteinBP3322Q7VU182
Putative binding-protein-dependent transport protein (Periplasmic)BP3237Q7VU862
Putative biopolymer transport ExbD2 proteinexbD2 Smlt0012B2FT902
Putative c'cytochromeBP2889Q7VV212
Putative capsular polysaccharide export proteinwza BP1628Q7VXV02
Putative carbohydrate kinaseVSAK1_25215A6CZ992
Putative carboxy-terminal processing proteasectpA BP0609Q7VS412
Putative carboxypeptidase YodJ (EC 3.4.-.-)yodJ yokZ BSU19620O348662
Putative cell division protein FtsNVSAK1_09503A6D0E12
Putative cell surface proteinBP2219Q7VWJ62
Putative cell-division ATP-binding proteinftsE SPy_0644Q9A0S42
Putative class II pilin PilEpilE Smlt3758B2FRS82
Putative cyclaseBP3130Q7VUG62
Putative cyclohexadienyl dehydratase signal peptide proteinVSAK1_24575A6D4122
Putative cyclomaltodextrin glucanotransferase (EC 2.4.1.19)amyA SPy_1302Q99ZB32
Putative cysteine aminopeptidase CpepC SPy_1651Q99YL02
Putative cytochromeBP2490Q7VVZ02
Putative cytochromeBP2491Q7VVY92
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