EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)sucA B195_20300M5QEL71
2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)odhA SAOUHSC_01418Q2FYM11
2-oxoglutarate dehydrogenase, E1 component (EC 1.2.4.2)sucA MXAN_6035Q1CZK31
2-oxoisovalerate dehydrogenase E1 component subunit alphaB195_09132M5R0U41
2-oxoisovalerate dehydrogenase subunit betaB195_09127M5QJ831
2-oxoisovalerate dehydrogenase subunit beta (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta)bfmBAB bfmB1b BSU24040P379411
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC synthase) (EC 2.2.1.9) (Menaquinone biosynthesis protein MenD)menD Rv0555P9WK111
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB (EC 2.1.1.185) (23S rRNA (guanosine2251 2'-O)-methyltransferase) (23S rRNA Gm2251 2'-O-methyltransferase)rlmB VSAK1_09923A6D8C51
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD (EC 2.1.1.190) (23S rRNA(m5U1939)-methyltransferase)rlmD VSAK1_07994A6D8G91
23S rRNA methyltransferase J (Fragment)rrmJ VSAK1_11033A6D8P71
27 kDa outer membrane protein (HopV protein)hopV omP27Q9X7491
28 kDa outer membrane protein Omp28PGN_0122B2RGZ61
29 kDa antigen CFP29cfp29 Rv0798cI6WZG61
3'-5' exoribonuclease YhaM (EC 3.1.-.-)yhaM lmo2220Q8Y5561
3'-5' ssDNA/RNA exonuclease TatD (EC 3.1.11.-) (EC 3.1.13.-) (DNase TatD)tatD SSON_4014Q3YVC61
3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12)ribB YPO0658 y3520 YP_2973Q8ZI561
3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12)ribB PA4054Q9HWX41
3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10) (Type I DHQase) (Type I dehydroquinase) (DHQ1)aroD SPy_0809 M5005_Spy0624P635901
3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10) (Type II DHQase)aroQ Fphi_0275B0TZ521
3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10) (Type II DHQase)aroQ B195_03553M5QPJ41
3-dehydroquinate synthase (EC 4.2.3.4)aroB PA5038P340021
3-dehydroquinate synthase (EC 4.2.3.4)aroB SPy_1577 M5005_Spy1298Q99YR31
3-dehydroquinate synthase (EC 4.2.3.4)aroB CD630_18330Q187E41
3-dehydroshikimate dehydratase (EC 4.2.1.118)quiC J560_2453A0A062EWV41
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC (EC 3.1.3.45) (KDO 8-P phosphatase)yrbI FTN_0905A0Q6C81
3-deoxy-D-manno-octulosonic-acid transferaseVSAK1_09673A6D0H51
3-Deoxy-D-manno-octulosonic-acid transferase (EC 2.-.-.-)kdtA FTT_1561Q5NEQ81
3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (CMP-2-keto-3-deoxyoctulosonic acid synthase) (CKS) (CMP-KDO synthase)kdsB FTN_0683A0Q5R01
3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.88)B195_17884M5QVY01
3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.88)mvaS.1 SPy_0880Q9A0941
3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.88)SAOUHSC_02859Q2FV771
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase (EC 2.3.1.245)lsrF YPO0408 y3773 YP_3773Q7CG471
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase (EC 2.3.1.245)lsrF SCH_3967Q57HD91
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ Fphi_1199B0TXG61
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ FTN_1479A0Q7Y11
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ CPF_1329Q0TRG51
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ STM0227P0A1H91
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ YPO1055 y3124 YP_2795Q8ZH571
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ SSON_0192Q3Z5H81
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ SPy_1746 M5005_Spy1487P641101
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ OOM_0745I2AYI71
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)fabZ SAOUHSC_02336Q2FWF51
3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55)crt CJD_2911B1V3D11
3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)hbd CD630_10580Q18AQ71
3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD)fadB2 Rv0468P9WNP71
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA) (Beta-hydroxydecanoyl thioester dehydrase) (Trans-2-decenoyl-[acyl-carrier-protein] isomerase) (EC 5.3.3.14)fabA B195_07982M5QJ801
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA) (Beta-hydroxydecanoyl thioester dehydrase) (Trans-2-decenoyl-[acyl-carrier-protein] isomerase) (EC 5.3.3.14)fabA PP_4174Q88FC41
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA) (Beta-hydroxydecanoyl thioester dehydrase) (Trans-2-decenoyl-[acyl-carrier-protein] isomerase) (EC 5.3.3.14)fabA YPO1430 y2740 YP_0875Q8ZG801
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA) (Beta-hydroxydecanoyl thioester dehydrase) (Trans-2-decenoyl-[acyl-carrier-protein] isomerase) (EC 5.3.3.14)fabA SFV_0962Q0T6811
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)FTT_1666cQ5NEG91
3-hydroxyisobutyrate dehydrogenase (HIBADH) (EC 1.1.1.31)B195_03887M5R2Q91
3-hydroxyisobutyrate dehydrogenase (HIBADH) (EC 1.1.1.31)mmsB PA3569P288111
3-isopropylmalate dehydratase large subunit (EC 4.2.1.-) (EC 4.2.1.33)leuC FTN_0061A0Q4071
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)leuC PA3121Q9HZA31
3-isopropylmalate dehydrogenase (EC 1.1.1.85)leuB FTN_0059A0Q4051
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)leuB NMB1031Q9JZI91
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)leuB Rv2995c MTV012.09P9WKK91
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)leuB PA3118Q513751
3-ketoacyl-(Acyl-carrier-protein) reductase (EC 1.1.1.100)fabG B195_09896M5QGK91
3-ketoacyl-(Acyl-carrier-protein) reductase (EC 1.1.1.100)fabG VSAK1_06765A6D1W11
3-ketoacyl-acyl carrier protein reductaseSC1083_1609G4A9U01
3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (KPHMT)panB FTN_1352A0Q7L21
3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (KPHMT)panB B195_04462M5R3331
3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (KPHMT)panB SSON_0142Q3Z5M61
3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (KPHMT)panB KW89_815A0A0K2DVB11
3-oxoacyl-(Acyl carrier protein) synthase (EC 2.3.1.41)VSAK1_06770A6D1W21
3-oxoacyl-(Acyl carrier protein) synthase I (EC 2.3.1.41)B195_07977M5R0801
3-oxoacyl-(Acyl-carrier-protein) reductase (EC 1.1.1.100)fabG HPSD74_1210U4SHD61
3-oxoacyl-(Acyl-carrier-protein) reductase (EC 1.1.1.100)fabG FTT_1375Q5NF681
3-oxoacyl-(Acyl-carrier-protein) reductase, putative (EC 1.1.1.100)SAOUHSC_01199Q2FZ531
3-oxoacyl-[acyl-carrier protein] reductase (3-ketoacyl-acyl carrier protein reductase) (EC 1.1.1.100)fabG CD630_11820Q18B451
3-oxoacyl-[acyl-carrier-protein] synthase 1 (EC 2.3.1.41) (3-oxoacyl-[acyl-carrier-protein] synthase I) (Beta-ketoacyl-ACP synthase I) (KAS I)fabB fabC b2323 JW2320P0A9531
3-oxoacyl-[acyl-carrier-protein] synthase 1 (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase 1) (KAS 1)kasA Rv2245 MTCY427.26P9WQD91
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)Fphi_1347B0TY111
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)fabF-1 NMB0219Q9K1D81
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)fabF1 PA2965G3XDA21
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)fabF SPy_1748Q99YD71
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)SAOUHSC_00921Q2FZR91
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179)fabF FTT_1377Q5NF661
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179) (3-oxoacyl-[acyl-carrier-protein] synthase II) (Beta-ketoacyl-ACP synthase II) (KAS II)fabF fabJ b1095 JW1081P0AAI51
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase 2) (KAS 2)kasB Rv2246 MTCY427.27P9WQD71
3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III)fabH FTN_1337A0Q7J71
3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III)fabH YPO1597 y1756 YP_2257Q8ZFT71
3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III)fabH SPy_1754 M5005_Spy1494Q99YD21
3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III)fabH FTT_1373Q5NF701
3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III)fabH LMRG_01630C0LNR01
3-oxoacyl-[acyl-carrier-protein] synthase IfabB SCH_2380Q57LX61
3-oxoacyl-[acyl-carrier-protein] synthase I (Beta-ketoacyl-[acyl-carrier-protein] synthase I)fabB S2534 SF2399 AJR25_001120 AJR27_002885Q83QQ91
3-oxoacyl-[acyl-carrier-protein] synthase I (EC 2.3.1.41)fabB YPO2757Q7CJB11
3-oxoacyl-[acyl-carrier-protein] synthase I (EC 4.1.2.13)fbaB STM2141Q7CQ971
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS)aroA SPy_1352 M5005_Spy1101Q99Z831
30S ribosomal protein S1rpsA jhp_0982Q9ZKF61
30S ribosomal protein S1Fphi_0665B0TVX71
30S ribosomal protein S1rpsA KPN_00938A6T7031
30S ribosomal protein S1rpsA ABSDF1738B0VN011
30S ribosomal protein S1rpsA B195_20705M5QTF81
30S ribosomal protein S1rpsA YPO1392Q7CHJ61
30S ribosomal protein S1rpsA SF0907 S0971P0AG701
30S ribosomal protein S1rpsA Rv1630 MTCY01B2.22P9WH431
30S ribosomal protein S1SC1083_0646G4A7551
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