EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
ABC transporter, membrane proteinFTT_1247Q5NFI71
ABC transporter, NBP/MSD fusion proteinSP70585_1294C1C7L01
ABC transporter, permease/ATP-binding proteinCPC_0392B1BGK01
ABC transporter, permease/ATP-binding proteinAC1_0597B1R3S11
ABC transporter, permease/ATP-binding proteinAC3_0499B1BNT01
ABC transporter, substrate-binding proteinAC1_2647B1R3N81
ABC transporter, substrate-binding proteinAC3_1668B1BRM71
ABC transporter, substrate-binding proteinCD196_1859A0A0H3N7W81
ABC transporter, substrate-binding protein, family 5 (ABC-type transport system, oligopeptide-family solute-binding protein) (Oligopeptide-binding protein AppA)appA appA_1 BN1095_250054 BN1096_520027 BN1097_680156 SAMEA3374989_00890 SAMEA3375059_00056A0A069AL861
ABC transporter, substrate-binding protein, putativeSAOUHSC_00634Q2G2D81
ABC transporter-related proteinETAE_2124D0Z9I31
ABC transporter: Outer membrane protein (OMP)VS_II0860B7VSP31
ABC transporter: Substrate-binding protein Maltooligosaccharides uptakeVS_II0220B7VQI91
ABC transporter: TonB-dependant outer membrane receptorVS_II0501B7VRB51
ABC-2 type transport system permeaseLMRG_01329A0A0H3GHE61
ABC-transporter (ATP-binding protein)-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharidergpDc SPy_0790Q9A0G21
ABC-type anion transport system, duplicated permease componentFTN_0140A0Q4861
ABC-type oligopeptide transport system, periplasmic componentoppA FTN_1593A0Q8881
ABC-type phosphate transport system, periplasmic componentVSAK1_14212A6D7361
ABC-type transport system permease proteinFTN_1266A0Q7D21
ABC-type transport system, aminoacid-family extracellular solute-binding proteinCD630_07500Q189U71
ABC-type transport system, aminoacid-family permeaseCD630_07510Q189U61
ABC-type transport system, glycine betaine/carnitine/choline ATP-binding protein (EC 3.6.3.-) (Glycine betaine/L-proline transport ATP-binding protein ProV) (Glycine betaine/carnitine/choline/choline sulfate ABC transporter (ATP-binding protein))opuCA proV BN1096_340023 BN1097_350027 SAMEA3374989_02111A0A069A4U81
ABC-type transport system, methionine-specific substrate-binding lipoproteinmetQ CD630_14910Q18C111
ABC-type transport system, multidrug-family ATP-binding protein (EC 3.6.3.-)CD630_21050Q188H31
ABC-type transport system, sugar-family extracellular solute-binding proteinCD630_26450Q182Y01
ABC-type transport system,cystine/aminoacid-family extracellular solute-binding proteinCD630_21740Q185W21
ABC-type transport system,cystine/aminoacid-family extracellular solute-binding proteinCD630_21770Q185W51
ABC-type transport system,nitrate/sulfonate/taurine extracellular solute-binding proteinCD630_23650Q185N51
AccC proteinaccC KPR_4851R4YI801
Acetate kinaseKU39_630A0A0K2L0X81
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA MW1654Q8NW531
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA FTN_0125A0Q4711
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA Cj0689Q9PPL81
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA AC3_2203B1BW701
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA S2507 SF2372 AJR25_000975 AJR27_002740Q83KB01
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA SC1083_0750G4A7F41
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA SPy_0109 M5005_Spy0094P634151
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA SCH_2338Q57M181
Acetate kinase (EC 2.7.2.1) (Acetokinase)ackA SAOUHSC_01820Q2FXL51
Acetate permeaseactP-I PP_1743Q88M321
Acetoacetate decarboxylaseFTN_0808A0Q6311
Acetoacetate decarboxylase (EC 4.1.1.4)Fphi_1806B0U0T01
Acetolactate synthase (EC 2.2.1.6)ilvB FTN_1042A0Q6R41
Acetolactate synthase (EC 2.2.1.6)ilvB spr0401Q8DR051
Acetolactate synthase (EC 2.2.1.6)VSAK1_05125A6D3481
Acetyl CoA carboxylase, biotin carboxylase subunitaccC SCH_3318Q57J881
Acetyl xylan esterase/carboyhdrate-binding protein, CBM6 familyFSU_3103D9S8961
Acetyl-CoA acetyltransferasefadA FTN_1439A0Q7U21
Acetyl-CoA acetyltransferasepaaJ KPN_01478A6T8I91
Acetyl-CoA acetyltransferaseB195_15954M5QWH31
Acetyl-CoA acetyltransferaseCPC_2507B1BK981
Acetyl-CoA acetyltransferase (EC 2.3.1.9)B195_16939M5QW661
Acetyl-CoA acetyltransferase (EC 2.3.1.9)MXAN_3791Q1D5V01
Acetyl-CoA acetyltransferase (EC 2.3.1.9)VSAK1_25625A6D2N71
Acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)thlA CD630_10590Q18AR01
Acetyl-CoA acetyltransferase, putativeSAOUHSC_00195Q2G1D01
Acetyl-CoA C-acetyltransferase family protein (EC 2.3.1.9)KW89_1096A0A0K2DW271
Acetyl-CoA carboxylase biotin carboxylase subunit (EC 6.4.1.2)B195_03543M5R3U41
Acetyl-CoA carboxylase, biotin carboxy carrier protein subunitFphi_0274B0TZ511
Acetyl-CoA carboxylase, biotin carboxy carrier protein subunitaccB FTN_0563A0Q5E31
Acetyl-CoA carboxylase, biotin carboxy carrier protein subunit (EC 4.1.1.3)OOM_1141I2AZH71
Acetyl-CoA carboxylase, biotin carboxyl carrier proteinaccB HPSD74_1426U4SHW31
Acetyl-CoA carboxylase, biotin carboxylaseB195_07680M5R2501
Acetyl-CoA carboxylase, biotin carboxylase (EC 6.3.4.14)accC NMB1861Q9JXW31
Acetyl-CoA carboxylase, biotin carboxylase (EC 6.4.1.2)accC HPSD74_1424U4SI251
Acetyl-CoA carboxylase, biotin carboxylase subunit (EC 6.3.4.14)OOM_1142I2AZH81
Acetyl-CoA carboxylase, biotin carboxylase subunit (EC 6.4.1.2)accC FTT_0473Q5NHI11
Acetyl-CoA carboxylase, biotin carboxylase, putative (EC 6.4.1.2)SAOUHSC_01709Q2FXX11
Acetyl-CoA carboxylase-biotin carboxylase subunit (EC 6.3.4.14) (EC 6.4.1.2)accC PP_0558Q88QD61
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 2.1.3.15)accA FTT_1498cQ5NEV91
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 6.4.1.2)accA Fphi_1134B0TXA01
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 6.4.1.2)accA Cj0443Q9PI621
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 6.4.1.2)accA NGK_0989B4RLH91
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 6.4.1.2)accA b0185 JW0180P0ABD51
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 6.4.1.2)accA SPy_1743Q99YE11
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 6.4.1.2)accA OOM_0718I2AYG31
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC 6.4.1.2)accA KU39_736A0A0K2L1791
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 2.1.3.15)accD SAOUHSC_01809Q2FXM61
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 6.4.1.2)accD Cj0127cQ0PC101
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 6.4.1.2)accD STM2366Q7CQ411
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 6.4.1.2)accD dedB usg b2316 JW2313P0A9Q51
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 6.4.1.2)accD SFV_2385Q0T2G91
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 6.4.1.2)accD SPy_1744 M5005_Spy1485Q99YE01
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 6.4.1.2)accD KW89_1919A0A0K2DYF51
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC 6.4.1.2)accD FTT_0372cQ5NHS31
Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme)acsA B195_06660M5QKM51
Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme)acs YPO0253 y0510 YP_0406Q8D1G81
Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme)acs yfaC b4069 JW4030P275501
Acetyl-coenzyme A synthetase 2 (AcCoA synthetase 2) (Acs 2) (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acyl-activating enzyme 2)acsA2 acsB PA4733Q9HV661
Acetylornithine aminotransferase (ACOAT) (EC 2.6.1.11)argD B195_06695M5QY011
Acetylornithine aminotransferase (ACOAT) (EC 2.6.1.11)argD Rv1655 MTCY06H11.20P9WPZ71
Acetylornithine deacetylase (EC 3.5.1.-) (EC 3.5.1.16)argE MXAN_1012Q1DDK01
AcetyltransferaseVSAK1_25830A6D2S81
Acetyltransferase (EC 2.3.1.-)FTT_0180Q5NIA11
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)Fphi_1186B0TXF31
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)aceF KPN_00119A6T4Q81
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)aceF NMB1342Q9JZ111
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)B195_02843M5R3F51
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)aceF STM14_0184A0A0F6AWU91
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