EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)aceF YPO3418Q7CKE51
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)pdhC MXAN_2668Q1D8Y61
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)SC1083_0758G4A7G21
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)aceF HPSD74_0593U4SK211
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)OOM_0732I2AYH51
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)pdhB Smlt4121B2FHZ81
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)aceF SCH_0152Q57TA31
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)KW89_2863A0A0K2E1B41
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)aceF FTT_1484cQ5NEX31
Acetyltransferase domain protein (EC 2.3.1.-)KW89_2616A0A0K2E0J11
Acetyltransferase protein (EC 2.3.1.-)FTT_1762cQ5NE891
Acetyltransferase protein (EC 2.3.1.-)FTT_1763cQ5NE881
Acid phosphataseFTN_0090A0Q4361
Acid phosphatase (EC 3.1.3.2)apy phoN2 AJR25_022340 SF_p0004Q599091
Acid phosphatase (Precursor) (EC 3.1.4.3)acpA FTT_0221Q5NI661
Acid stress chaperone HdeAhdeA SSON_3576Q3YWI41
Acid stress chaperone HdeA (10K-S protein)hdeA yhhC yhiB b3510 JW3478P0AES91
Acid stress chaperone HdeBhdeB YPO2674Q7CJS41
Acid stress chaperone HdeB (10K-L protein)hdeB yhhD yhiC b3509 JW5669P0AET21
Aconitate hydratase (Aconitase) (EC 4.2.1.3)Fphi_0995B0TWW11
Aconitate hydratase (Aconitase) (EC 4.2.1.3)citBQ8Y6P31
Aconitate hydratase (Aconitase) (EC 4.2.1.3)acnA B195_21010M5QCG51
Aconitate hydratase (Aconitase) (EC 4.2.1.3)acnA-I PP_2112Q88L241
Aconitate hydratase (Aconitase) (EC 4.2.1.3)acnA MXAN_1363Q1DCK31
Aconitate hydratase (Aconitase) (EC 4.2.1.3)VSAK1_25720A6D2Q61
Aconitate hydratase (Aconitase) (EC 4.2.1.3)SAOUHSC_01347Q2FYS91
Aconitate hydratase (Aconitase) (EC 4.2.1.3)acnA FTT_0087Q5NII11
Aconitate hydratase (EC 4.2.1.3)B195_10151M5QID41
Aconitate hydratase A (ACN) (Aconitase) (EC 4.2.1.3) ((2R,3S)-2-methylisocitrate dehydratase) ((2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase) (Iron-responsive protein-like) (IRP-like) (Probable 2-methyl-cis-aconitate hydratase) (EC 4.2.1.99) (RNA-binding protein)citB BSU18000P093391
Aconitate hydratase A (ACN) (Aconitase) (EC 4.2.1.3) ((2R,3S)-2-methylisocitrate dehydratase) ((2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase) (Iron-responsive protein-like) (IRP-like) (Probable 2-methyl-cis-aconitate hydratase) (EC 4.2.1.99) (RNA-binding protein)acn Rv1475c RVBD_1475c P425_01532O531661
Aconitate hydratase A (ACN) (Aconitase) (EC 4.2.1.3) (Iron-responsive protein-like) (IRP-like) (RNA-binding protein) (Stationary phase enzyme)acnA acn b1276 JW1268P255161
Aconitate hydratase B (ACN) (Aconitase) (EC 4.2.1.3) ((2R,3S)-2-methylisocitrate dehydratase) ((2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase) (2-methyl-cis-aconitate hydratase) (EC 4.2.1.99) (Iron-responsive protein-like) (IRP-like) (RNA-binding protein)acnB jhp_0716Q9ZL641
Aconitate hydratase B (ACN) (Aconitase) (EC 4.2.1.3) ((2R,3S)-2-methylisocitrate dehydratase) ((2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase) (2-methyl-cis-aconitate hydratase) (EC 4.2.1.99) (Iron-responsive protein-like) (IRP-like) (RNA-binding protein)acnB HP_0779P564181
Aconitate hydratase B (EC 4.2.1.3) (EC 4.2.1.99) (2-methylisocitrate dehydratase)acnB A7M79_18965 A7M90_03665 A7N09_10040 AB895_0156 AB988_4026 ABUW_1593 APD06_10270 APD31_09210 AZE33_12810 BGC29_08480 IX87_06625 LV38_01480B0V7B91
Aconitate hydratase B (EC 4.2.1.3) (EC 4.2.1.99) (2-methylisocitrate dehydratase)acnB NMB1572Q9JYI41
Aconitate hydratase B (EC 4.2.1.3) (EC 4.2.1.99) (2-methylisocitrate dehydratase)B195_07445M5QYB71
Aconitate hydratase B (EC 4.2.1.3) (EC 4.2.1.99) (2-methylisocitrate dehydratase)acnB PP_2339Q88KF11
Aconitate hydratase B (EC 4.2.1.3) (EC 4.2.1.99) (2-methylisocitrate dehydratase)acnB YPO3415Q7CKE21
Aconitate hydratase B (EC 4.2.1.3) (EC 4.2.1.99) (2-methylisocitrate dehydratase)acnB SSON_0126Q3Z5P21
AcrA proteinSC1083_0112G4A5M71
Acridine efflux pumpacrA SCH_0518Q57S871
Acriflavin resistance plasma membrane proteinVSAK1_07044A6D5561
Acriflavin resistance protein AcrFacrF KW89_120A0A0K2DSW91
Acriflavine resistance proteinSC1083_0113G4A5M81
Acyl carrier protein (ACP)acpP YPO1600 y1759 YP_2254Q8ZFT41
Acyl carrier protein (ACP)acpA acpP BSU15920P806431
Acyl carrier protein (ACP)acpP VSAK1_06705A6D1U91
Acyl carrier protein (ACP)acpP OOM_0914I2AYY41
Acyl carrier protein (ACP) (Cytosolic-activating factor) (CAF) (Fatty acid synthase acyl carrier protein)acpP b1094 JW1080P0A6A81
Acyl-CoA dehydrogenasefadE B195_10011M5QG441
Acyl-CoA dehydrogenase (EC 1.3.99.3)fadE FTT_1529Q5NET31
Acyl-CoA dehydrogenase FadE7fadE7 Rv0400cP952081
Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.-)acdB CD630_03990Q188I51
Acyl-CoA synthetase (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3)fadD1 FTT_1254Q5NFI01
Acyl-CoA thioester hydrolase-related proteinVSAK1_16497A6CUL01
Acyl-CoA thioesterase ItesA SSON_0484Q3Z4Q31
Acyl-coenzyme A dehydrogenase (ACDH) (EC 1.3.99.-)fadE YPO3244 y0946 YP_0688Q8ZBY61
Acyl-coenzyme A synthetase/AMP-(Fatty) acid ligaseFphi_1878B0U1851
Acyl-coenzyme A synthetase/AMP-(Fatty) acid ligasesacs FTN_0730A0Q5V61
Acyl-homoserine-lactone synthase (EC 2.3.1.184) (Autoinducer synthesis protein)VSAK1_16717A6CUQ41
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (EC 2.3.1.129)Fphi_1200B0TXG71
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (EC 2.3.1.129)lpxA FTT_1569cQ5NEQ11
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (UDP-N-acetylglucosamine acyltransferase) (EC 2.3.1.129)lpxA VSAK1_11720A6D8P01
AcyltransferaseFTN_1749A0Q8N51
Acyltransferase (EC 2.3.1.-)htrB FTT_0231cQ5NI581
Acyltransferase (EC 2.3.1.-)ddg FTT_0232cQ5NI571
Acyltransferase (EC 2.3.1.51)OOM_1800I2B1471
Acyltransferase familyOOM_0808I2AYM41
Adapter protein MecAmecA spr1220Q8DPE01
Adapter protein MecAmecA SAOUHSC_00935Q2G1U51
AdeK (Adenine deaminase) (Adenosine deaminase) (Efflux transporter, outer membrane factor (OMF) lipo, NodT family protein) (Multidrug efflux protein AdeK) (Outer membrane protein OprM) (RND efflux system, outer membrane lipoprotein CmeC)adeK oprM A7M79_01765 A7M90_18255 A7N09_11630 AB895_0719 AB988_0490 ABUW_0842 APD06_14010 APD31_14975 AZE33_16180 BGC29_00975 IX87_10265 LV38_03648Q24LT61
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)apt FTN_1633A0Q8C61
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)apt SPy_0927 M5005_Spy0728P635461
Adenine/cytosine DNA methyltransferaseHP_0054O248951
Adenosine kinase (ADK) (AK) (EC 2.7.1.20)adoK cbhK Rv2202c MTCY190.13cP9WID51
Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)ahcY B195_14540M5QU241
Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)ahcY MXAN_6516Q1CY841
Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)ahcY sahH Rv3248c MTCY20B11.23cP9WGV31
Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)sahH ahcY Smlt0775B2FPC31
Adenylate cyclase (EC 4.6.1.1)cyaA KPN_04305A6TGI91
Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk Fphi_0011B0TXR21
Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk CPF_2693Q0TMR71
Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk STM0488P0A1V41
Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk PP_1506P0A1361
Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk dnaW plsA b0474 JW0463P694411
Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk SPy_0074 M5005_Spy0065P698821
Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk Smlt3886B2FT481
Adenylosuccinate lyasepurB FTN_1694A0Q8I61
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase)purB Cj0023Q0PCA21
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase)purB spr0056Q8DRL71
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase)VSAK1_00155A6D5J41
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase)purB Smlt3193B2FLC81
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase)purB SPy_0036Q9A1Y31
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase)purB PA2629Q9I0K91
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase)purB SAOUHSC_02126Q2G2S01
Adenylosuccinate lyase (EC 4.3.2.2)Fphi_0911B0TWM61
Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)purA Fphi_0647B0TVV81
Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)purA FTN_0178A0Q4C31
Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)purA NMB0815Q9K0121
Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)purA YPO0378 y0635 YP_0534Q8ZIV71
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