EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA)surA SF0050 S0052P0ABZ91
Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA)surA ABSDF1713B0VMX61
Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA)surA J804_2789A0A014CU901
Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA)surA SCH_0087Q57TG81
Chemotactic transducer for trichloroethylene [positive chemotaxis], CttPcttP PA0180Q9I6V21
Chemotaxis CheVVSAK1_02924A6CX771
Chemotaxis proteincheW Cj0283cQ0PBM31
Chemotaxis proteinPJ16_01170A0A0B6V4N01
Chemotaxis protein CheVVSAK1_26845A6D7W71
Chemotaxis protein CheYcheY PA1456Q514551
Chemotaxis protein CheY homologcheY Cj1118cP0C6351
Chemotaxis protein histidine kinase CheAVSAK1_03144A6CXC11
Chemotaxis protein MotAmotA PA4954Q9HUL11
Chemotaxis protein MotBmotB PA4953Q9HUL21
Chemotaxis response regulator protein-glutamate methylesterase (EC 3.1.1.61)cheB VSAK1_03149A6CXC21
Chitin binding proteinFTT_0816cQ5NGL91
Chitin-binding proteincbpA FTN_1485A0Q7Y71
ChitinasechiB FTN_1744A0Q8N11
ChitinasechiC PA2300Q9I1H51
Chitinase (EC 3.2.1.14) (Putative chitinase)FSU_2012A7UG631
Chitinase family 18 protein (EC 3.2.1.-)FTT_0715Q5NGW21
Chloramphenicol acetyltransferaseB195_18096M5QDY11
Chloramphenicol acetyltransferase (CAT) (EC 2.3.1.28)catPP268261
Cholera enterotoxin subunit B (Cholera enterotoxin B chain) (Cholera enterotoxin gamma chain) (Choleragenoid)ctxB toxB VC_1456P015561
Choline / betaine / carnitine ABC transporter-substrate binding protein BetX (EC 3.6.3.32)betX PP_1741Q88M341
Choline dehydrogenaseB195_00985M5QQY51
Choline kinasepck spr1147Q8DPI41
Choloylglycine hydrolaseB195_21665M5QE761
Choloylglycine hydrolaseVSAK1_26010A6D0Z21
Choloylglycine hydrolase family proteinFTN_1252A0Q7B81
Choloylglycine hydrolase family protein (EC 3.5.1.-)FTT_1109Q5NFV91
Choloylglycine hydrolase family protein (EC 3.5.1.-)FTT_1234Q5NFK01
Chorismate mutase (EC 5.4.99.5)FTT_1650cQ5NEI41
Chorismate synthase (CS) (EC 4.2.3.5) (5-enolpyruvylshikimate-3-phosphate phospholyase)aroC Fphi_0436B0U0251
Chorismate synthase (CS) (EC 4.2.3.5) (5-enolpyruvylshikimate-3-phosphate phospholyase)aroC FTN_0402A0Q4Z01
Chorismate synthase (CS) (EC 4.2.3.5) (5-enolpyruvylshikimate-3-phosphate phospholyase)aroC VSAK1_03274A6CXE71
Chorismate synthase (CS) (EC 4.2.3.5) (5-enolpyruvylshikimate-3-phosphate phospholyase)aroC aroF SPy_0810 M5005_Spy0625Q9A0E41
Chromosomal replication initiator protein DnaAdnaA FTN_0001A0Q3U71
Chromosomal replication initiator protein DnaAdnaA SPy_0002 M5005_Spy0001P0A3A41
Chromosomal replication initiator protein DnaAdnaA OOM_0001I2AWN11
Chromosome partition protein MukB (Structural maintenance of chromosome-related protein)mukB b0924 JW0907P225231
Chromosome partition protein MukB (Structural maintenance of chromosome-related protein)mukB KPR_3627R4YCA41
Chromosome partition protein MukEmukE VSAK1_04097A6D7K41
Chromosome partition protein Smcsmc SP70585_1309C1C7M51
Chromosome partition protein Smcsmc SPCG_1056B2IPN61
Chromosome partition protein Smcsmc spr1126Q8DPJ91
Chromosome partitioning protein ParAparA KW89_28A0A0K2DT071
Chromosome partitioning protein ParBparB KW89_27A0A0K2DT481
Chromosome partitioning protein Sojsoj PA5563Q9HT111
Citrate lyase acyl carrier protein (Citrate lyase gamma chain)citD SPy_1186 M5005_Spy0905Q99ZK91
Citrate lyase alpha chain (Citrase alpha chain) (EC 2.8.3.10) (EC 4.1.3.6) (Citrate (pro-3S)-lyase alpha chain) (Citrate CoA-transferase subunit)citF SPy_1189Q99ZK71
Citrate lyase subunit beta-like protein (EC 4.1.-.-)citE Rv2498cP9WPE11
Citrate synthaseFphi_0968B0TWT31
Citrate synthasegltA FTN_1640A0Q8D31
Citrate synthasegltA Cj1682cQ0P7U81
Citrate synthasegltA B195_20275M5QEL11
Citrate synthaseB195_10156M5QUC51
Citrate synthasegltA PP_4194Q88FA41
Citrate synthasegltA YPO1108Q7CH411
Citrate synthasegltA S0590 SF0577 AJR25_003700 AJR27_005200A0A0H2VVH01
Citrate synthaseVSAK1_25715A6D2Q51
Citrate synthaseprpC Smlt3609B2FQH71
Citrate synthaseECs0745A0A0H3JCM91
Citrate synthasegltA SCH_0736Q57RL91
Citrate synthasegltA FTT_0071cQ5NIJ61
Citrate synthase (EC 2.3.3.16)gltA jhp_0022Q9ZN371
Citrate synthase (EC 2.3.3.16)gltA gluT icdB b0720 JW0710P0ABH71
Citrate synthase 1 (EC 2.3.3.16)gltA2 gltA Rv0896 MTCY31.24P9WPD51
Citrate-dependent iron transport, periplasmic proteinfecB SSON_4462Q3YU731
Class B acid phosphatase (EC 3.1.3.2)HPSD74_1865U4SAK31
Class B acid phosphatase (EC 3.1.3.2)KW89_2601A0A0K2E0H61
Class I outer membrane protein (PorA)porAQ7BMY61
Class one outer membrane protein (Fragment)porAQ055201
Class one outer membrane protein (Fragment)porAQ991171
ClpXP protease specificity-enhancing factor (Fragment)VSAK1_04855A6D9I41
CNP1-like family proteinNMH_2293E6N0H71
Co-chaperone HscBHPSD74_0969U4SKL91
Co-chaperone protein DjlAdjlA HPSD74_0021U4SM591
Co-chaperone protein DjlAdjlA VSAK1_07724A6D7991
Co/Zn/Cd cation transporterOOM_1404I2B0601
Coat proteinSCH_0357Q57SP81
Coat protein B of bacteriophage Pf1 (Phage coat protein B)coaB PA0723 PA4673.7Q9I5K51
Cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17)VSAK1_03474A6CXI71
CobQ/CobB/MinD/ParA nucleotide-binding domain proteinKW89_1p36A0A0K2E1Y31
Cobyric acid synthasecobQ PA1277Q9I4671
Cobyrinic acid a,c-diamide synthasecbiA PG_1163Q7MVB31
Cobyrinic acid ac-diamide synthaseETAE_2748D0ZD191
Coenzyme A biosynthesis bifunctional protein CoaBC (EC 4.1.1.36) (EC 6.3.2.5) (DNA/pantothenate metabolism flavoprotein)SAOUHSC_01178Q2G2681
Coenzyme A biosynthesis bifunctional protein CoaBC (EC 4.1.1.36) (EC 6.3.2.5) (DNA/pantothenate metabolism flavoprotein)dfp FTT_1147cQ5NFS81
Coenzyme PQQ synthesis protein D (Pyrroloquinoline quinone biosynthesis protein D)pqqD PA1988Q9I2C11
Cold shock proteincspC YPO1746Q74V471
Cold shock protein CspB (Major cold shock protein)cspB cspA BSU09100P320811
Cold shock protein CspDcspD BSU21930P517771
Cold-shock proteinPP_1209Q88NJ81
Collagen-like surface proteiscl SPy_1983Q7DAL31
ComB2 proteincomB2Q9ZEK91
ComEA protein (Fragment)comEAQ9XAZ41
Competence proteincelB spr0857Q8DQ401
Competence proteincglB spr1863Q8DN871
Component of chemotactic signal transduction systemchpA PA0413Q9I6961
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