EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
CRISPR-associated endonuclease Cpf1 (EC 3.1.-.-) (FnCpf1)cpf1 FTN_1397A0Q7Q21
CRISPR-associated protein Csy3csy3 csy1-3 PA14_33310Q02MM11
Cryptic nitrate reductase 2, alpha subunitnarZ SSON_1657Q3Z1L11
CsuEcsuEQ6XBY21
CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)pyrG ctrA MW2051P659241
CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)pyrG jhp_0323Q9ZM991
CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)pyrG spr0438Q8DQY01
CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)pyrG b2780 JW2751P0A7E51
CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)pyrG SPy_1894 M5005_Spy1610 M5005_Spy1609P659251
CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)pyrG SAOUHSC_02368Q2FWD11
Cu(I)-translocating P-type ATPasecopA KPN_00464A6T5P41
Curli production assembly/transport component CsgFVSAK1_16577A6CUM61
Curli production assembly/transport component CsgGVSAK1_16582A6CUM71
Curli production assembly/transport component CsgG family proteinHPSD74_1610U4SDH31
Curli production assembly/transport component CsgG family proteinKW89_2690A0A0K2E0571
Curli production assembly/transport component, 2nd curli operoncsgG SSON_1046Q3Z3891
CvpA family proteinLMRG_00676A0A0H3GBG01
Cwp13 (N-acetylmuramoyl-L-alanine amidase LytC) (EC 3.5.1.28)cwp13 lytC_25 SAMEA3374989_02948L7PG661
Cyanophycin synthetaseFphi_1494B0TYX31
Cyanophycin synthetase (EC 6.-.-.-)cphA FTT_1130cQ5NFT91
Cyclic AMP receptor proteincrp KPN_03743A6TEZ61
Cyclic di-GMP-binding protein (Cellulose synthase regulatory subunit)bcsB yhjN b3532 JW3500P376521
Cyclic nucleotide-binding domain proteinMXAN_6248Q1CYZ61
Cyclic nucleotide-binding domain proteinMXAN_6249Q1CYZ51
Cyclic pyranopterin monophosphate synthase (EC 4.6.1.17) (Molybdenum cofactor biosynthesis protein C)moaC Plav_3176A7HXZ91
Cyclic pyranopterin monophosphate synthase (EC 4.6.1.17) (Molybdenum cofactor biosynthesis protein C)moaC VSAK1_03690A6D3S61
Cyclopropane fatty acid synthase, methyltransferasecfa FTN_1456A0Q7V91
Cyclopropane mycolic acid synthase 2 (CMAS) (EC 2.1.1.79) (Cyclopropane-fatty-acyl-phospholipid synthase) (CFA synthase) (Cyclopropane fatty acid synthase) (Mycolic acid methyltransferase) (MA-MT) (S-adenosylmethionine-dependent methyltransferase) (AdoMet-MT) (SAM-MT)cmaA2 cma2 CMAS-2 Rv0503c MTCY20G9.30cP9WPB51
Cyclopropane-fatty-acyl-phospholipid synthaseB195_01210M5R4I31
CylM protein, cytolytic toxin systemcylM spr1767Q8DNF61
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase (EC 4.2.-.-)SPy_0599Q9A0V41
Cystathionine beta-lyase (EC 4.4.1.8)VSAK1_01262A6D2D81
Cystathionine gamma-synthase (CGS) (EC 2.5.1.48) (O-succinylhomoserine (thiol)-lyase)metB Rv1079 MTV017.32P9WGB71
Cystathionine gamma-synthase (CGS) (O-succinylhomoserine(Thiol)-lyase) (EC 2.5.1.48)SP70585_1564C1C8B61
Cystathionine gamma-synthase (EC 2.5.1.48)VSAK1_09473A6D0D51
Cysteine desulfurase (EC 2.8.1.7)SPy_0288Q9A1G31
Cysteine desulfurase (EC 2.8.1.7)sufS KW89_1440A0A0B8UQE61
Cysteine desulfurase IscS (EC 2.8.1.7)iscS CPC_2029B1BJ741
Cysteine desulfurase IscS (EC 2.8.1.7)iscS SC1083_0170G4A5T51
Cysteine desulfurase IscS (EC 2.8.1.7)yfhO iscS SSON_2612Q3YZ221
Cysteine desulfurase IscS (EC 2.8.1.7)iscS HPSD74_0331U4SJA71
Cysteine desulfurase IscS (EC 2.8.1.7)iscS_2 iscS SAMEA3374989_02403 SAMEA3375059_02465A0A160WY741
Cysteine desulfurase IscS (EC 2.8.1.7)iscS SCH_2537Q57LG91
Cysteine desulfurase IscS (EC 2.8.1.7) (NifS protein homolog) (ThiI transpersulfidase) (TusA transpersulfidase)iscS nuvC yfhO yzzO b2530 JW2514P0A6B71
Cysteine synthasecysK FTN_1302A0Q7G81
Cysteine synthase (EC 2.5.1.47)cysK AC1_1717B1RCB11
Cysteine synthase (EC 2.5.1.47)cysK PA2709Q9I0D31
Cysteine synthase (EC 2.5.1.47)cysK YPO2992Q7CJF51
Cysteine synthase (EC 2.5.1.47)cysK cysK_1 AGG09_21630 BB749_07505 BCB67_11260 BL143_04905 PMK1_00258 SAMEA3531778_01627 SM57_03014Q0ZB891
Cysteine synthase (EC 2.5.1.47)cysK HPSD74_2038U4SAY81
Cysteine synthase (EC 2.5.1.47)cysK SCH_2428Q57LS81
Cysteine synthase (EC 2.5.1.47)SAOUHSC_00488Q2G0Q81
Cysteine synthase ASC1083_1109G4A8G11
Cysteine synthase B (CSase B) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase B) (OAS-TL B) (O-acetylserine sulfhydrylase B)cysM Cj0912cP711281
Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)cysS Fphi_0516B0U0I31
Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)cysS spr0519Q8DQS81
Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)cysS PA1795Q9I2U71
Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)cysS SFV_0484Q0T7761
Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)cysS SPy_1941 M5005_Spy1655Q99XZ91
Cysteine-rich repeat proteinMXAN_1733Q1DBJ01
Cysteine/glutathione ABC transporter membrane/ATP-binding component (EC 3.6.3.44)OOM_1225I2AZQ11
Cytidylate kinase (CK) (EC 2.7.4.25) (Cytidine monophosphate kinase) (CMP kinase)cmk FTN_0956A0Q6H91
Cytochrome bpetB PP_1318Q88N941
Cytochrome b561PP_2010Q88LC51
Cytochrome b562 family proteinHPSD74_2051U4S9Z61
Cytochrome bd ubiquinol oxidase subunit 2 (EC 1.10.3.-) (Cytochrome d ubiquinol oxidase subunit II)cydB yxkL BSU38750P943651
Cytochrome bd ubiquinol oxidase subunit ISC1083_1311G4A9051
Cytochrome bd-II terminal oxidase subunit IappC FTN_1619A0Q8B31
Cytochrome bo(3) ubiquinol oxidase subunit 2 (Cytochrome b562-o complex subunit II) (Cytochrome o ubiquinol oxidase subunit 2) (Cytochrome o subunit 2) (Oxidase bo(3) subunit 2) (Ubiquinol oxidase chain B) (Ubiquinol oxidase polypeptide II) (Ubiquinol oxidase subunit 2)cyoA b0432 JW0422P0ABJ11
Cytochrome c biogenesis ATP-binding export protein CcmA (EC 3.6.3.41) (Heme exporter protein A)ccmA VSAK1_03174A6CXC71
Cytochrome c oxidase subunit (Cbb3-type)PA4133Q9HWP81
Cytochrome c oxidase subunit 1 (EC 1.9.3.1)ctaD PP_0104Q88RM51
Cytochrome c oxidase subunit 2 (EC 1.9.3.1)PP_0103Q88RM61
Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Caa-3605 subunit 2) (Cytochrome aa3 subunit 2) (Cytochrome c oxidase polypeptide II) (Oxidase aa(3) subunit 2)ctaC BSU14890P240111
Cytochrome c oxidase subunit I, cbb3-type (EC 1.9.3.1)ccoN-II PP_4255Q88F441
Cytochrome c oxidase, subunit III (EC 1.9.3.1)coxC MXAN_6088Q1CZF01
Cytochrome c-552 (EC 1.7.2.2)nrfA Cj1357cQ0P8Q21
Cytochrome c-553 (Cytochrome c553)jhp_1148Q9ZJZ91
Cytochrome c-type biogenesis protein CcmE (Cytochrome c maturation protein E) (Heme chaperone CcmE)ccmE cycJ PP_4323Q88EX91
Cytochrome c-type biogenesis protein CcmE (Cytochrome c maturation protein E) (Heme chaperone CcmE)ccmE cycJ PA1479Q9I3N31
Cytochrome c-type biogenesis protein CcmE (Cytochrome c maturation protein E) (Heme chaperone CcmE)ccmE cycJ HPSD74_2113U4SB691
Cytochrome c-type biogenesis protein CcmE (Cytochrome c maturation protein E) (Heme chaperone CcmE)ccmE cycJ VSAK1_03194A6CXD11
Cytochrome c-type biogenesis protein CcmFVSAK1_03199A6CXD21
Cytochrome c-type biogenesis protein CcmHccmH PA1482Q9I3N01
Cytochrome c-type protein TorCtorC b0996 JW0981P332261
Cytochrome c-type protein TorYtorY yecK b1873 JW1862P520051
Cytochrome c5NMB1677Q9JYA21
Cytochrome C551 peroxidase (EC 1.11.1.5)Cj0020cQ0PCA51
Cytochrome d terminal oxidase polypeptide subunit IcydA SSON_0685Q3Z4711
Cytochrome d terminal oxidase polypeptide subunit I (Cytochrome d terminal oxidase, polypeptide subunit I)cydA ECs0768 Z0900Q8X9791
Cytochrome d terminal oxidase polypeptide subunit IIcydB SCH_0745Q57RL01
Cytochrome d terminal oxidase, polypeptide subunit IcydA SCH_0744Q57RL11
Cytochrome d terminal oxidase, polypeptide subunit I (EC 1.10.3.-)cydA FTT_0279cQ5NI131
Cytochrome d ubiquinol oxidase subunit IOOM_0172I2AX341
Cytochrome d ubiquinol oxidase, subunit I, putativeSAOUHSC_01031Q2FZH31
Cytochrome d ubiquinol oxidase, subunit II, putative (EC 1.10.3.-)SAOUHSC_01032Q2FZH21
Cytochrome o ubiquinol oxidase subunit IcyoB SCH_0484Q57SC11
Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)cyoB FTT_0282Q5NI101
Cytochrome o ubiquinol oxidase, subunit IVSAK1_06660A6D1U01
Cytochrome oxidase (CBB3-TYPE)fixN jhp_0132Q9ZMT61
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