This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P97461 3.5e-9 3.6e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 3.3e-15 2.7e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt) (bMRP-27a) (bMRP27a)Q9Y2R9 0.0e+0 4.9e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 2.6e-3Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 3.6e-1Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)Q5I0K8 0.0e+0 3.3e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)Q80X85 0.0e+0 3.3e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)Q80X85 0.0e+0 4.3e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P97461 0.0e+0 2.6e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P97461 0.0e+0 9.5e-2Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P97461 0.0e+0 8.7e-2Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 1.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 9.0e-2Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 4.3e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 3.0e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt) (bMRP-27a) (bMRP27a)Q9Y2R9 0.0e+0 4.0e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 2.3e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 3.9e-2Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 4.2e-2Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 1.1e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)Q80X85 0.0e+0 4.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)Q80X85 0.0e+0 3.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)Q80X85 0.0e+0 3.3e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt) (bMRP-27a) (bMRP27a)Q9Y2R9 0.0e+0 1.1e-1Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 4.5e-7Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 0.0e+0Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		COG004922 / 0 / 22
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt) (bMRP-27a) (bMRP27a)Q9Y2R9 0.0e+0 3.8e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 3.4e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG004922 / 0 / 22
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]P46782 0.0e+0 6.0e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG004922 / 0 / 22
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