This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)Q9Y3D2 7.0e-11 7.2e-2Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.-)Q8IXL7 8.0e-10 1.0e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)Q9NZV6 0.0e+0 4.4e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)Q9Y3D2 0.0e+0 3.6e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)Q9NZV6 0.0e+0 2.3e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.-)Q8IXL7 0.0e+0 4.8e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.-)Q8IXL7 0.0e+0 4.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)Q9Y3D2 1.8e-2 1.4e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.-)Q8IXL7 3.2e-2 2.5e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)Q9NZV6 0.0e+0 4.6e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)Q9NZV6 2.2e-16 4.8e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)Q9Y3D2 0.0e+0 2.2e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)Q9Y3D2 0.0e+0 2.4e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)Q9NZV6 0.0e+0 8.0e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)Q9Y3D2 0.0e+0 4.3e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)Q9NZV6 0.0e+0 1.1e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG022911 / 0 / 11
Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)Q9Y3D2 0.0e+0 5.0e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG022911 / 0 / 11
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