This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Bifunctional apoptosis regulator (RING finger protein 47)Q9NZS9 1.2e-8 3.9e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		COG280214 / 0 / 14
Bifunctional apoptosis regulator (RING finger protein 47)Q9NZS9 0.0e+0 2.1e-4Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		COG280214 / 0 / 14
LON peptidase N-terminal domain and RING finger protein 2 (Neuroblastoma apoptosis-related protease) (RING finger protein 192)Q1L5Z9 0.0e+0 3.2e-7Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		COG280214 / 0 / 14
Bifunctional apoptosis regulatorQ8R079 0.0e+0 3.8e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG280214 / 0 / 14
Bifunctional apoptosis regulatorQ8R079 0.0e+0 3.5e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG280214 / 0 / 14
E3 ubiquitin-protein ligase RNF168 (EC 6.3.2.-) (RING finger protein 168)Q80XJ2 0.0e+0 4.5e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG280214 / 0 / 14
Bifunctional apoptosis regulatorQ8R079 2.9e-4 4.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		COG280214 / 0 / 14
Bifunctional apoptosis regulatorQ8R079 0.0e+0 4.8e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		COG280214 / 0 / 14
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 6.3.2.-) (RING finger protein 168)Q8IYW5 0.0e+0 3.6e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG280214 / 0 / 14
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 6.3.2.-) (RING finger protein 168)Q8IYW5 3.8e-13 4.3e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG280214 / 0 / 14
LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)Q17RB8 1.9e-2 1.5e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG280214 / 0 / 14
LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)Q17RB8 4.9e-2 2.2e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG280214 / 0 / 14
E3 ubiquitin-protein ligase RNF168 (EC 6.3.2.-) (RING finger protein 168)Q80XJ2 0.0e+0 1.2e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		COG280214 / 0 / 14
E3 ubiquitin-protein ligase RNF168 (EC 6.3.2.-) (RING finger protein 168)Q80XJ2 0.0e+0 1.9e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		COG280214 / 0 / 14
LON peptidase N-terminal domain and RING finger protein 3 (RING finger protein 127)Q496Y0 0.0e+0 7.2e-12Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		COG280214 / 0 / 14
LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)Q17RB8 0.0e+0 4.5e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG280214 / 0 / 14
LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)Q17RB8 0.0e+0 3.0e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG280214 / 0 / 14
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