This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)Q8VDF2 1.8e-4 5.0e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		COG34407 / 0 / 7
E3 ubiquitin-protein ligase UHRF2 (EC 6.3.2.-) (NIRF) (Np95-like ring finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)Q7TMI3 1.2e-5 4.6e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		COG34407 / 0 / 7
E3 ubiquitin-protein ligase UHRF2 (EC 6.3.2.-) (NIRF) (Np95-like ring finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)Q7TMI3 5.1e-8 3.9e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		COG34407 / 0 / 7
E3 ubiquitin-protein ligase UHRF2 (EC 6.3.2.-) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)Q96PU4 8.1e-6 4.7e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		COG34407 / 0 / 7
E3 ubiquitin-protein ligase UHRF2 (EC 6.3.2.-) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)Q96PU4 4.6e-8 1.8e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		COG34407 / 0 / 7
Protein Uhrf2 (Ubiquitin-like, containing PHD and RING finger domains 2 (Predicted))D3ZK36 0.0e+0 4.5e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		COG34407 / 0 / 7
E3 ubiquitin-protein ligase UHRF2 (EC 6.3.2.-) (NIRF) (Np95-like ring finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)Q7TMI3 0.0e+0 4.1e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG34407 / 0 / 7
E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)Q8VDF2 3.7e-5 4.6e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		COG34407 / 0 / 7
E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)Q8VDF2 2.5e-5 4.1e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		COG34407 / 0 / 7
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