EVpedia 2.0

This menu provides the list of EV mRNAs identified by high-throughput analyses.

Search:

Superdomain: All Prokaryote Eukaryote

Filter datasets:
- "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
- "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).

Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
    Please see user manual in the contact us/help menu for detail.

Number of molecules in one page:

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name	UniProt accession	FPR	TPR	Publication	Orthologous group	Identification count All / Prokaryote / Eukaryote (FPR<0.05,TPR<0.5)
E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1)	Q86TM6	3.5e-6	4.6e-1	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.	COG5243	12 / 0 / 12
Putative uncharacterized protein DKFZp547B0914 (Fragment)	Q8NDT8	5.9e-12	3.3e-1	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196)	Q96EP1	0.0e+0	4.6e-1	Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.	COG5243	12 / 0 / 12
Protein LOC100910831 (Syvn1 protein)	B2RYC4	0.0e+0	4.6e-1	Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase AMFR (EC 6.3.2.-) (Autocrine motility factor receptor) (AMF receptor)	Q9R049	0.0e+0	3.4e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase RNF139 (EC 6.3.2.-) (RING finger protein 139) (Translocation in renal carcinoma on chromosome 8 protein)	Q7TMV1	0.0e+0	4.3e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1)	Q9DBY1	0.0e+0	2.5e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	COG5243	12 / 0 / 12
RING finger protein 145	Q5SWK7	0.0e+0	4.4e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase RNF139 (EC 6.3.2.-) (RING finger protein 139) (Translocation in renal carcinoma on chromosome 8 protein)	Q8WU17	0.0e+0	4.2e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196)	Q96EP1	4.7e-2	8.9e-2	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196)	Q96EP1	3.3e-2	5.6e-2	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196)	Q96EP1	1.2e-2	9.2e-2	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196)	Q96EP1	4.3e-2	1.9e-1	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1)	Q86TM6	3.3e-16	4.8e-1	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1)	Q86TM6	0.0e+0	4.4e-1	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.	COG5243	12 / 0 / 12
E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196)	Q96EP1	0.0e+0	4.9e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	COG5243	12 / 0 / 12

[1]