This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Protein Iqgap3F8VQ29 2.5e-8 3.8e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 9.1e-9 3.7e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 5.9e-6 4.5e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1 (p195)P46940 0.0e+0 3.1e-3Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 0.0e+0 4.9e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 0.0e+0 4.0e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 1.3e-5 4.5e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 6.1e-11 3.2e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 1.8e-12 2.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 1.2e-7 3.3e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1Q9JKF1 8.0e-6 3.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP3Q86VI3 0.0e+0 4.8e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP3Q86VI3 0.0e+0 4.7e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1 (p195)P46940 0.0e+0 4.1e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1 (p195)P46940 0.0e+0 4.6e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP3Q86VI3 0.0e+0 4.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1 (p195)P46940 7.2e-11 4.6e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1 (p195)P46940 2.7e-5 4.7e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP2Q13576 1.6e-10 3.4e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1 (p195)P46940 0.0e+0 2.0e-7Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.
COG526112 / 0 / 12
Ras GTPase-activating-like protein IQGAP1 (p195)P46940 0.0e+0 3.8e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
COG526112 / 0 / 12
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