This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Transcription factor E2F5 (E2F-5)Q61502 0.0e+0 8.5e-2Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 9.3e-11 3.5e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 6.0e-8 4.1e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 2.9e-5 4.9e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)Q01094 0.0e+0 4.7e-5Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F5 (E2F-5)Q15329 2.7e-8 1.7e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 1.0e-4 4.8e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 0.0e+0 4.9e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F3 (E2F-3)O35261 0.0e+0 4.3e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F5 (E2F-5)Q61502 0.0e+0 4.7e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 4.4e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 3.9e-9 3.6e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 1.1e-4 4.8e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F5 (E2F-5)Q61502 0.0e+0 1.6e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 3.8e-5 4.2e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F5 (E2F-5)Q61502 0.0e+0 5.5e-2Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 0.0e+0 4.3e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 0.0e+0 4.1e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 0.0e+0 2.5e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)P56931 0.0e+0 1.9e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)P56931 0.0e+0 2.8e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 2.1e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 6.5e-2Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 1.1e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F3 (E2F-3)O00716 0.0e+0 5.0e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F3 (E2F-3)O00716 0.0e+0 3.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 0.0e+0 3.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)Q01094 8.1e-10 4.7e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F3 (E2F-3)O00716 0.0e+0 3.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F3 (E2F-3)O00716 0.0e+0 3.3e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 1.1e-13 4.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 3.3e-2 4.4e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 3.1e-2 5.1e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)Q14209 2.8e-2 2.2e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F3 (E2F-3)O00716 3.5e-2 2.7e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F4 (E2F-4)Q16254 3.4e-2 2.6e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 8.9e-3 6.5e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 1.6e-2 4.8e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)Q01094 3.6e-10 3.5e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 0.0e+0 6.1e-6Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)P56931 0.0e+0 2.2e-3Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)P56931 0.0e+0 1.1e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 2.1e-4Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 6.9e-4Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 0.0e+0 1.1e-4Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)P56931 0.0e+0 5.2e-3Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)P56931 0.0e+0 2.7e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 6.6e-5Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 3.4e-5Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F1 (E2F-1)Q61501 0.0e+0 4.1e-3Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F2 (E2F-2)P56931 0.0e+0 2.0e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 3.7e-5Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA)O54917 0.0e+0 1.9e-3Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 0.0e+0 0.0e+0Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F4 (E2F-4)Q16254 0.0e+0 1.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 0.0e+0 3.9e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F4 (E2F-4)Q16254 0.0e+0 2.6e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XNYI22 / 0 / 22
Transcription factor E2F6 (E2F-6)O75461 0.0e+0 2.3e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XNYI22 / 0 / 22
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