This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9QXT5 2.1e-11 3.1e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XP6K23 / 0 / 23
Protein jagged-2 (Jagged2)Q9QYE5 8.9e-5 4.9e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XP6K23 / 0 / 23
Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3)Q9NYJ7 3.6e-5 4.9e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410XP6K23 / 0 / 23
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9UHF1 7.9e-11 7.4e-2Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410XP6K23 / 0 / 23
Notch homolog 2 N-terminal-like proteinQ7Z3S9 6.5e-14 2.4e-2Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410XP6K23 / 0 / 23
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)P78504 1.5e-6 2.9e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1)Q9NQ36 3.3e-9 1.3e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410XP6K23 / 0 / 23
Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3)Q9NYJ7 0.0e+0 3.0e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		ENOG410XP6K23 / 0 / 23
Protein jagged-2 (Jagged2) (hJ2)Q9Y219 0.0e+0 4.7e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		ENOG410XP6K23 / 0 / 23
Protein jagged-1 (Jagged1) (CD antigen CD339)Q9QXX0 0.0e+0 4.2e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XP6K23 / 0 / 23
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9QXT5 2.3e-5 4.6e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XP6K23 / 0 / 23
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9QXT5 1.3e-5 4.0e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XP6K23 / 0 / 23
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9QXT5 9.5e-4 4.8e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XP6K23 / 0 / 23
Cryptic protein (Cryptic family protein 1)P0CG37 0.0e+0 5.0e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.		ENOG410XP6K23 / 0 / 23
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9QXT5 0.0e+0 2.4e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XP6K23 / 0 / 23
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)P78504 2.3e-11 4.5e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XP6K23 / 0 / 23
Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3)Q9NYJ7 3.7e-2 6.7e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XP6K23 / 0 / 23
Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]P80370 4.3e-2 9.0e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XP6K23 / 0 / 23
Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3)Q9NYJ7 1.6e-2 1.3e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XP6K23 / 0 / 23
Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]P80370 4.9e-2 3.7e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XP6K23 / 0 / 23
Protein jagged-2 (Jagged2) (hJ2)Q9Y219 4.4e-2 3.3e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XP6K23 / 0 / 23
Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3)Q9NYJ7 3.0e-2 1.2e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XP6K23 / 0 / 23
Notch homolog 2 N-terminal-like proteinQ7Z3S9 3.3e-16 4.8e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410XP6K23 / 0 / 23
Delta-like 1 homolog (Drosophila)Q969Y6 5.4e-15 4.9e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410XP6K23 / 0 / 23
Fibulin-7 (FIBL-7)Q53RD9 0.0e+0 4.0e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410XP6K23 / 0 / 23
Notch homolog 2 N-terminal-like proteinQ7Z3S9 0.0e+0 4.0e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410XP6K23 / 0 / 23
Notch homolog 2 N-terminal-like proteinQ7Z3S9 0.0e+0 4.0e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410XP6K23 / 0 / 23
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9QXT5 0.0e+0 3.3e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)Q9QXT5 0.0e+0 4.3e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Putative uncharacterized proteinQ3UZP8 0.0e+0 2.1e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2D3YVM9 0.0e+0 2.7e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Putative uncharacterized proteinQ3UZP8 0.0e+0 7.3e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2D3YVM9 0.0e+0 4.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Putative uncharacterized proteinQ3UZP8 0.0e+0 8.6e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Putative uncharacterized proteinQ3UZP8 0.0e+0 4.2e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2D3YVM9 0.0e+0 1.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1)Q9NQ36 0.0e+0 0.0e+0Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG410XP6K23 / 0 / 23
Teratocarcinoma-derived growth factor 1 (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1)P13385 0.0e+0 5.7e-2Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1)Q9NQ36 0.0e+0 4.7e-3Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1)Q9NQ36 0.0e+0 2.3e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XP6K23 / 0 / 23
Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1)Q9NQ36 0.0e+0 1.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XP6K23 / 0 / 23
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