This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)Q86UP8 0.0e+0 7.8e-16Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)Q86UP8 0.0e+0 3.8e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)Q86UP8 0.0e+0 4.3e-2Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.
ENOG410XPSC17 / 0 / 17
EPM2A-interacting protein 1 (Laforin-interacting protein)Q8VEH5 0.0e+0 4.1e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2 (GTF2I repeat domain-containing protein 2) (Transcription factor GTF2IRD2)Q99NI3 0.0e+0 4.8e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2 (GTF2I repeat domain-containing protein 2) (Transcription factor GTF2IRD2)Q99NI3 0.0e+0 4.4e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)Q86UP8 0.0e+0 4.0e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)Q86UP8 0.0e+0 2.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 3.8e-2 5.9e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 2.3e-2 2.9e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 6.3e-3 4.2e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 1.1e-2 2.8e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 0.0e+0 3.3e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 0.0e+0 4.1e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 0.0e+0 3.2e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 0.0e+0 4.0e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)Q86UP8 2.7e-5 4.7e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.
ENOG410XPSC17 / 0 / 17
EPM2A-interacting protein 1 (Laforin-interacting protein)Q8VEH5 0.0e+0 3.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XPSC17 / 0 / 17
EPM2A-interacting protein 1 (Laforin-interacting protein)Q8VEH5 0.0e+0 4.9e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XPSC17 / 0 / 17
EPM2A-interacting protein 1 (Laforin-interacting protein)Q8VEH5 0.0e+0 4.0e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XPSC17 / 0 / 17
EPM2A-interacting protein 1 (Laforin-interacting protein)Q8VEH5 0.0e+0 4.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XPSC17 / 0 / 17
General transcription factor II-I repeat domain-containing protein 2B (GTF2I repeat domain-containing protein 2B) (Transcription factor GTF2IRD2-beta)Q6EKJ0 0.0e+0 3.1e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410XPSC17 / 0 / 17
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