This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
MCG12357 (Protein Pabpc4l)G5E8X2 5.1e-10 3.4e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 1.1e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 1.4e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 2.7e-9 3.6e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 2.5e-6 4.3e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 8.6e-8 4.1e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 1.1e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 3.8e-2Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 2.5e-2Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)Q9H361 0.0e+0 1.2e-1Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)Q9EPH8 0.0e+0 4.5e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 3.7e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XR5X24 / 0 / 24
Poly A binding protein, cytoplasmic 2 (Poly(A) binding protein, cytoplasmic 2) (PolyA binding protein, testis-enriched isoform) (Protein Pabpc2)Q62029 0.0e+0 4.1e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 0.0e+0 2.2e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 2.2e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 1.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 0.0e+0 1.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 2.7e-6 4.3e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 3.0e-13 2.0e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 9.7e-14 1.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 3.0e-10 2.6e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 2.0e-7 3.3e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 2.8e-2Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 0.0e+0 3.6e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 1.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)Q9H361 0.0e+0 1.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)Q13310 0.0e+0 2.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 1.0e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)Q9H361 0.0e+0 8.2e-2Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)Q13310 0.0e+0 2.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1-like 2 (RNA-binding motif protein 32) (RNA-binding protein 32)Q5JQF8 3.0e-2 3.6e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1-like 2 (RNA-binding motif protein 32) (RNA-binding protein 32)Q5JQF8 3.6e-2 6.5e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1-like 2 (RNA-binding motif protein 32) (RNA-binding protein 32)Q5JQF8 3.0e-2 2.4e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1-like 2 (RNA-binding motif protein 32) (RNA-binding protein 32)Q5JQF8 6.0e-3 4.0e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1-like 2 (RNA-binding motif protein 32) (RNA-binding protein 32)Q5JQF8 2.0e-2 7.1e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)Q13310 0.0e+0 4.2e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 1.9e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)Q9H361 0.0e+0 1.8e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 2.9e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 0.0e+0 2.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XR5X24 / 0 / 24
MCG5546, isoform CRA_c (Poly(A) binding protein, cytoplasmic 4) (Protein Pabpc4)Q6PHQ9 0.0e+0 1.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 0.0e+0 2.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P29341 0.0e+0 2.8e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 5 (PABP-5) (Poly(A)-binding protein 5)Q96DU9 0.0e+0 3.6e-13Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)Q9H361 0.0e+0 5.6e-10Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 3.5e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)Q13310 0.0e+0 1.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)P11940 0.0e+0 6.1e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XR5X24 / 0 / 24
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)Q13310 0.0e+0 7.8e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410XR5X24 / 0 / 24
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