EVpedia 2.0

This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote

Filter datasets:
- "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
- "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).

Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
    Please see user manual in the contact us/help menu for detail.

Number of molecules in one page:

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name	UniProt accession	FPR	TPR	Publication	Orthologous group	Identification count All / Prokaryote / Eukaryote (FPR<0.05,TPR<0.5)
DENN domain-containing protein 2A	Q9ULE3	7.1e-9	3.9e-1	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2A	Q9ULE3	2.1e-9	3.8e-1	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2C	Q68D51	3.1e-13	3.0e-1	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.	ENOG410XT3N	13 / 0 / 13
KIAA1608 protein (Fragment)	Q9HCG4	4.2e-8	4.1e-1	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2C	Q68D51	9.2e-6	3.6e-1	Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.	ENOG410XT3N	13 / 0 / 13
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B) (HeLa tumor suppression 1)	P78524	1.2e-7	2.1e-1	Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.	ENOG410XT3N	13 / 0 / 13
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B) (HeLa tumor suppression 1)	P78524	1.2e-7	2.1e-1	Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.	ENOG410XT3N	13 / 0 / 13
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B) (HeLa tumor suppression 1)	P78524	0.0e+0	1.1e-3	Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A)	Q8TEH3	0.0e+0	4.4e-1	Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn)	Q8K382	0.0e+0	4.6e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn)	Q8K382	0.0e+0	4.1e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2A	Q8C4S8	0.0e+0	3.6e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	ENOG410XT3N	13 / 0 / 13
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B)	Q924W7	0.0e+0	5.0e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1B (Connecdenn 2) (Protein FAM31B)	Q6P3S1	0.0e+0	4.8e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XT3N	13 / 0 / 13
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B) (HeLa tumor suppression 1)	P78524	0.0e+0	5.0e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1B (Connecdenn 2) (Protein FAM31B)	Q6P3S1	2.2e-8	4.9e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2D	Q9H6A0	2.7e-2	2.1e-1	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2D	Q9H6A0	4.3e-2	1.9e-1	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1C (Connecdenn 3)	Q8CFK6	0.0e+0	1.5e-1	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1C (Connecdenn 3)	Q8CFK6	0.0e+0	8.6e-2	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2A	Q8C4S8	0.0e+0	4.6e-1	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 1C (Connecdenn 3)	Q8CFK6	0.0e+0	1.8e-4	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2D	Q9H6A0	0.0e+0	5.8e-2	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410XT3N	13 / 0 / 13
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B) (HeLa tumor suppression 1)	P78524	0.0e+0	3.2e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2A	Q9ULE3	0.0e+0	4.5e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410XT3N	13 / 0 / 13
DENN domain-containing protein 2D	Q9H6A0	0.0e+0	1.1e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410XT3N	13 / 0 / 13
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B) (HeLa tumor suppression 1)	P78524	0.0e+0	2.4e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410XT3N	13 / 0 / 13

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