This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Number of molecules in one page:

The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
BTB/POZ domain-containing protein KCTD17Q8N5Z5 2.2e-7 4.2e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerization domain-containing protein 2)Q14681 0.0e+0 7.0e-3Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerization domain-containing protein 2)Q14681 0.0e+0 7.0e-3Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q9NXV2 0.0e+0 0.0e+0Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q9NXV2 0.0e+0 2.6e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.
ENOG410XT4J14 / 0 / 14
KCTD2 protein (Fragment)Q8IYY2 0.0e+0 4.9e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD17Q8N5Z5 0.0e+0 4.9e-1Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 4.5e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 4.5e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD17Q8N5Z5 6.7e-10 4.7e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q9NXV2 3.7e-2 2.9e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410XT4J14 / 0 / 14
KCTD2 protein (Fragment)Q8IYY2 2.1e-14 5.0e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q9NXV2 0.0e+0 3.7e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q9NXV2 0.0e+0 3.8e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 1.7e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 2.8e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 4.3e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 2.0e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 5.7e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XT4J14 / 0 / 14
BTB/POZ domain-containing protein KCTD5Q8VC57 0.0e+0 9.4e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410XT4J14 / 0 / 14
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