This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
BTB/POZ domain-containing protein KCTD1Q5M956 9.6e-8 4.0e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD11Q8K485 3.1e-5 4.7e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)Q96CX2 1.6e-12 3.2e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z15518 / 0 / 18
Potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4)Q8N5I3 3.8e-7 4.3e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)Q96CX2 1.4e-15 1.3e-2Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD14Q9BQ13 0.0e+0 1.1e-5Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410Z15518 / 0 / 18
Potassium channel tetramerisation domain containing 8 (Predicted) (Potassium channel tetramerization domain containing 8) (Protein Kctd8)A6Y7S3 0.0e+0 4.3e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD6Q8BNL5 0.0e+0 4.6e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410Z15518 / 0 / 18
Potassium channel tetramerisation domain containing 12b (Potassium channel tetramerisation domain containing 12b, isoform CRA_a) (Protein Kctd12b)Q8C7J6 0.0e+0 3.8e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD1Q5M956 1.2e-5 3.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD18Q6PI47 0.0e+0 4.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)Q96CX2 7.4e-13 4.3e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD14Q9BQ13 4.1e-2 6.8e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD14Q9BQ13 3.1e-2 4.9e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD14Q9BQ13 2.2e-2 1.8e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD14Q9BQ13 4.4e-2 2.0e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)Q96SI1 2.2e-16 4.8e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)Q96SI1 0.0e+0 3.4e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD11Q8K485 0.0e+0 3.1e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)Q8K0E1 0.0e+0 1.3e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD6Q8BNL5 0.0e+0 2.1e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD11Q8K485 0.0e+0 3.0e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)Q8K0E1 0.0e+0 4.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
Potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4)Q2TUM3 0.0e+0 4.7e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
Potassium channel tetramerisation domain containing 14 (Potassium channel tetramerization domain containing 14) (Protein Kctd14)Q5EER8 0.0e+0 3.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD6Q8BNL5 0.0e+0 4.2e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
Potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4)Q2TUM3 0.0e+0 2.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
Potassium channel tetramerisation domain containing 14 (Potassium channel tetramerization domain containing 14) (Protein Kctd14)Q5EER8 0.0e+0 3.0e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
Potassium channel tetramerisation domain containing 18, isoform CRA_a (Protein Kctd18)E0CZ26 0.0e+0 4.1e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z15518 / 0 / 18
BTB/POZ domain-containing protein KCTD6Q8NC69 0.0e+0 4.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG410Z15518 / 0 / 18
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