This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
E3 ubiquitin-protein ligase RNF128 (EC 6.3.2.-) (Gene related to anergy in lymphocytes protein) (RING finger protein 128)Q8TEB7 2.6e-5 4.8e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 1.9e-7 4.2e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 1.3e-7 4.2e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167) (RING105)Q9H6Y7 1.5e-5 4.8e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167) (RING105)Q9H6Y7 1.2e-6 4.4e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z5DF13 / 0 / 13
Ring finger protein 148 (Ring finger protein 148, isoform CRA_b)A4D0X4 1.3e-5 4.7e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z5DF13 / 0 / 13
Zinc/RING finger protein 4 (RING finger protein 204)Q8WWF5 0.0e+0 1.7e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 7.7e-14 2.5e-2Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 0.0e+0 4.4e-16Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167) (RING105)Q9H6Y7 0.0e+0 3.9e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167) (RING105)Q9H6Y7 0.0e+0 3.6e-1Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167)Q5XIL0 0.0e+0 4.2e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167)Q5XIL0 0.0e+0 4.8e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O54965 0.0e+0 4.6e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF128 (EC 6.3.2.-) (Gene related to anergy in lymphocytes protein) (Goliath-related E3 ubiquitin-protein ligase 1) (RING finger protein 128)Q9D304 1.9e-5 4.5e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 0.0e+0 4.5e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 0.0e+0 4.5e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167) (RING105)Q9H6Y7 0.0e+0 4.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 2.2e-14 4.1e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (RING finger protein 13)O43567 0.0e+0 3.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167) (RING105)Q9H6Y7 0.0e+0 3.7e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167)Q91XF4 0.0e+0 3.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z5DF13 / 0 / 13
E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167)Q91XF4 0.0e+0 4.3e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG410Z5DF13 / 0 / 13
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