EVpedia 2.0

This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote

Filter datasets:
- "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
- "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).

Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
    Please see user manual in the contact us/help menu for detail.

Number of molecules in one page:

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name	UniProt accession	FPR	TPR	Publication	Orthologous group	Identification count All / Prokaryote / Eukaryote (FPR<0.05,TPR<0.5)
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog)	Q6S5J6	3.8e-6	4.4e-1	Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog)	Q6S5J6	2.1e-6	4.3e-1	Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	7.8e-8	4.1e-1	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)	O00522	4.4e-5	4.3e-1	Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)	O00522	0.0e+0	4.5e-1	Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	0.0e+0	2.6e-1	Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q5U2R3	0.0e+0	4.6e-1	Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q5U2R3	0.0e+0	3.6e-1	Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q3UFK8	0.0e+0	3.9e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q3UFK8	0.0e+0	3.3e-1	Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog)	Q6S5J6	7.1e-5	4.3e-1	Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	0.0e+0	3.4e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)	O00522	0.0e+0	4.6e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)	O00522	0.0e+0	4.4e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	1.5e-8	4.9e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	2.6e-2	2.6e-2	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	1.5e-2	1.1e-2	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	2.5e-3	1.2e-2	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	6.3e-3	1.1e-2	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog)	Q6S5J6	0.0e+0	8.9e-2	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog)	Q6S5J6	0.0e+0	1.3e-1	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410ZV6V	20 / 0 / 20
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog)	Q6S5J6	0.0e+0	6.3e-2	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	0.0e+0	2.2e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410ZV6V	20 / 0 / 20
FERM domain-containing protein 8	Q9BZ67	0.0e+0	3.2e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410ZV6V	20 / 0 / 20

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