This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Protein Tob2 (Transducer of erbB-2 2)Q9JM55 1.8e-6 4.3e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.
ENOG410ZZC024 / 0 / 24
Protein Tob2 (Transducer of erbB-2 2)Q9JM55 4.6e-6 4.4e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.
ENOG410ZZC024 / 0 / 24
Protein Tob2 (Protein Tob4) (Transducer of erbB-2 2)Q14106 0.0e+0 2.3e-3Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.
ENOG410ZZC024 / 0 / 24
B-cell translocation gene 1, anti-proliferative (B-cell translocation gene 1, anti-proliferative, isoform CRA_b) (BTG1) (BTG1 protein) (cDNA, FLJ93822, Homo sapiens B-cell translocation gene 1, anti-proliferative(BTG1), mRNA)Q6IBC8 0.0e+0 3.1e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.
ENOG410ZZC024 / 0 / 24
BTG family, member 3, isoform CRA_b (BTG3 protein) (cDNA FLJ75072, highly similar to Homo sapiens BTG family, member 3 (BTG3), mRNA)Q6IAU3 0.0e+0 2.4e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.
ENOG410ZZC024 / 0 / 24
Protein Tob1 (Transducer of erbB-2 1)P50616 0.0e+0 4.3e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62324 0.0e+0 1.6e-1Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)P78543 0.0e+0 4.6e-3Nanostructural and transcriptomic analyses of human saliva derived exosomes.
PLoS One. 2010 Jan 5;5(1):e8577. doi: 10.1371/journal.pone.0008577.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (Anti-proliferative factor) (B-cell translocation gene 1 protein)Q63073 0.0e+0 2.9e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)P27049 0.0e+0 2.3e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.
ENOG410ZZC024 / 0 / 24
Protein Tob2 (Transducer of ERBB2, 2)Q5U4F2 0.0e+0 2.5e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (Anti-proliferative factor) (B-cell translocation gene 1 protein)Q63073 0.0e+0 3.7e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)P27049 0.0e+0 3.6e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.
ENOG410ZZC024 / 0 / 24
Protein Tob2 (Transducer of ERBB2, 2)Q5U4F2 0.0e+0 3.2e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 0.0e+0 2.4e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 0.0e+0 4.4e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible protein TIS21)Q04211 0.0e+0 5.0e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible protein TIS21)Q04211 0.0e+0 4.4e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410ZZC024 / 0 / 24
Protein Tob2 (Transducer of erbB-2 2)Q9JM55 0.0e+0 4.9e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410ZZC024 / 0 / 24
Protein Tob2 (Transducer of erbB-2 2)Q9JM55 0.0e+0 4.5e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 2.7e-5 4.6e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
ENOG410ZZC024 / 0 / 24
Protein Tob2 (Transducer of erbB-2 2)Q9JM55 3.3e-5 4.6e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 2.1e-3 5.0e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 0.0e+0 4.9e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62324 0.0e+0 2.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62324 0.0e+0 2.6e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 4.1e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 3.5e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein Tob1 (Transducer of erbB-2 1)P50616 0.0e+0 4.0e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62324 0.0e+0 2.8e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 2.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 3.8e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein Tob1 (Transducer of erbB-2 1)P50616 2.3e-13 4.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62324 1.9e-2 1.5e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)P78543 4.5e-2 3.4e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 1.0e-2 7.4e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 2.8e-2 1.1e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG410ZZC024 / 0 / 24
B-cell translocation gene 1, anti-proliferative (B-cell translocation gene 1, anti-proliferative, isoform CRA_b) (BTG1) (BTG1 protein) (cDNA, FLJ93822, Homo sapiens B-cell translocation gene 1, anti-proliferative(BTG1), mRNA)Q6IBC8 0.0e+0 4.6e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.
ENOG410ZZC024 / 0 / 24
B-cell translocation gene 1, anti-proliferative (B-cell translocation gene 1, anti-proliferative, isoform CRA_b) (BTG1) (BTG1 protein) (cDNA, FLJ93822, Homo sapiens B-cell translocation gene 1, anti-proliferative(BTG1), mRNA)Q6IBC8 0.0e+0 4.0e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.
ENOG410ZZC024 / 0 / 24
Protein Tob1 (Transducer of erbB-2 1)P50616 1.3e-14 4.9e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 2.2e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 2.3e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 7.4e-5 4.8e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.
ENOG410ZZC024 / 0 / 24
Protein 4930430D24Rik (Uncharacterized protein)Q3V0X0 0.0e+0 3.1e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 0.0e+0 4.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)P50615 0.0e+0 3.2e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410ZZC024 / 0 / 24
Protein 4930430D24Rik (Uncharacterized protein)Q3V0X0 0.0e+0 3.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 0.0e+0 4.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410ZZC024 / 0 / 24
Protein 4930430D24Rik (Uncharacterized protein)Q3V0X0 0.0e+0 1.9e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62325 0.0e+0 1.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62324 0.0e+0 9.1e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)P78543 0.0e+0 4.0e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 2.8e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
Protein Tob1 (Transducer of erbB-2 1)P50616 0.0e+0 1.1e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
Protein BTG1 (B-cell translocation gene 1 protein)P62324 0.0e+0 2.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)P78543 0.0e+0 2.5e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)Q14201 0.0e+0 2.6e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
Protein Tob1 (Transducer of erbB-2 1)P50616 0.0e+0 1.2e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.
ENOG410ZZC024 / 0 / 24
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