This menu provides the list of EV mRNAs identified by high-throughput analyses.

Search:
Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q9D123 8.2e-5 4.9e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q9NWD8 5.9e-6 4.6e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q86XT9 0.0e+0 3.7e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q6AY76 0.0e+0 3.5e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q9D123 0.0e+0 3.3e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q9D123 0.0e+0 5.0e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q3TBN1 0.0e+0 4.3e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q3TBN1 0.0e+0 3.1e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q3TBN1 2.7e-11 3.1e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q3TBN1 7.1e-5 4.7e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q3TBN1 0.0e+0 2.2e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q9D123 1.4e-3 4.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q3TBN1 1.2e-3 4.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG411015513 / 0 / 13
Transmembrane protein 248Q3TBN1 4.3e-8 3.1e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q86XT9 4.4e-2 7.5e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q86XT9 3.7e-2 6.9e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q86XT9 3.3e-3 1.9e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q86XT9 1.6e-2 4.9e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q86XT9 0.0e+0 7.7e-3The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG411015513 / 0 / 13
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)Q86XT9 0.0e+0 5.7e-3The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG411015513 / 0 / 13
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