This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
E3 ubiquitin-protein ligase TTC3 (Tetratricopeptide repeat domain 3, isoform CRA_b)G5E8T2 2.9e-6 4.4e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 5.3e-8 4.1e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 2.0e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (Tetratricopeptide repeat domain 3, isoform CRA_b)G5E8T2 2.4e-7 4.0e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (Tetratricopeptide repeat domain 3, isoform CRA_b)G5E8T2 1.5e-8 3.7e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (Tetratricopeptide repeat domain 3, isoform CRA_b)G5E8T2 4.2e-6 4.3e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (Tetratricopeptide repeat domain 3, isoform CRA_b)G5E8T2 4.5e-8 3.1e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 3.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 3.7e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 3.5e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 3.3e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 3.3e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 2.5e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 3.1e-10 4.7e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 2.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 3.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 1.3e-4 4.9e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 1.5e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG41103HK10 / 0 / 10
E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (Protein DCRR1) (RING finger protein 105) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)P53804 0.0e+0 1.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG41103HK10 / 0 / 10
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