This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 8.3e-12 3.0e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG4111HZ416 / 0 / 16
CDC42 effector protein (Rho GTPase binding) 4, isoform CRA_a (cDNA FLJ14479 fis, clone MAMMA1002143, highly similar to Cdc42 effector protein 4 (Binder of Rho GTPases 4)) (cDNA, FLJ92905, Homo sapiens CDC42 effector protein (Rho GTPase binding) 4(CDC42EP4), mRNA)B2R6D8 7.0e-5 5.0e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 0.0e+0 5.0e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 0.0e+0 4.5e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 1.0e-8 3.7e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 1.6e-9 2.8e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111HZ416 / 0 / 16
CDC42 effector protein (Rho GTPase binding) 4, isoform CRA_a (cDNA FLJ14479 fis, clone MAMMA1002143, highly similar to Cdc42 effector protein 4 (Binder of Rho GTPases 4)) (cDNA, FLJ92905, Homo sapiens CDC42 effector protein (Rho GTPase binding) 4(CDC42EP4), mRNA)B2R6D8 0.0e+0 2.8e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.		ENOG4111HZ416 / 0 / 16
CDC42 effector protein (Rho GTPase binding) 4, isoform CRA_a (cDNA FLJ14479 fis, clone MAMMA1002143, highly similar to Cdc42 effector protein 4 (Binder of Rho GTPases 4)) (cDNA, FLJ92905, Homo sapiens CDC42 effector protein (Rho GTPase binding) 4(CDC42EP4), mRNA)B2R6D8 0.0e+0 2.6e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9H3Q1 2.9e-2 3.3e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9H3Q1 4.0e-2 7.8e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9H3Q1 1.8e-2 1.5e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9H3Q1 2.3e-2 8.4e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 0.0e+0 5.3e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 0.0e+0 1.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9JM96 0.0e+0 1.4e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9H3Q1 0.0e+0 1.0e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111HZ416 / 0 / 16
Cdc42 effector protein 4 (Binder of Rho GTPases 4)Q9H3Q1 0.0e+0 5.4e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111HZ416 / 0 / 16
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