This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
    Please see user manual in the contact us/help menu for detail.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia)Q9UKJ5 0.0e+0 2.1e-1Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA.
Blood. 2007 Oct 1;110(7):2440-8. Epub 2007 May 29.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia)Q9UKJ5 1.2e-13 3.0e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein)Q5VXU3 1.2e-4 4.8e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia)Q9UKJ5 0.0e+0 4.6e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia)Q9UKJ5 0.0e+0 3.9e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 proteinQ9D9G3 0.0e+0 4.1e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 proteinQ9D9G3 2.7e-4 4.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 proteinQ9D9G3 1.7e-3 4.9e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 proteinQ9D9G3 0.0e+0 3.5e-1Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 proteinQ9D9G3 0.0e+0 9.9e-2Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.
PLoS One. 2012;7(4):e34653. doi: 10.1371/journal.pone.0034653. Epub 2012 Apr 10.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia)Q9UKJ5 1.9e-2 1.5e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia)Q9UKJ5 0.0e+0 4.6e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia)Q9UKJ5 0.0e+0 4.5e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein)Q8CBW7 0.0e+0 9.3e-3Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein)Q8CBW7 0.0e+0 6.2e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG4111JK615 / 0 / 15
Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein)Q8CBW7 0.0e+0 5.8e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.
ENOG4111JK615 / 0 / 15
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