This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
E74-like factor 5 (Ets domain transcription factor), isoform CRA_a (cDNA FLJ78106, highly similar to Homo sapiens E74-like factor 5 (ets domain transcription factor) (ELF5), transcript variant 2, mRNA) (cDNA FLJ90716 fis, clone PLACE1008549, highly similar to ETS-related transcription factor Elf-5) (cDNA, FLJ92906, Homo sapiens E74-like factor 5 (ets domain transcription factor)(ELF5), mRNA)A8K443 1.7e-7 4.2e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG4111K4J19 / 0 / 19
Putative uncharacterized protein DKFZp686H0575Q6MZZ4 6.8e-6 4.7e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P41212 1.0e-14 2.8e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG4111K4J19 / 0 / 19
ETS homologous factor (hEHF) (ETS domain-containing transcription factor) (Epithelium-specific Ets transcription factor 3) (ESE-3)Q9NZC4 4.5e-6 3.3e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)P78545 1.3e-5 3.8e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)Q9UKW6 0.0e+0 0.0e+0Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 0.0e+0 3.9e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P41212 0.0e+0 3.2e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P97360 7.1e-5 4.7e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111K4J19 / 0 / 19
ETS homologous factor (ETS domain-containing transcription factor)O70273 1.0e-3 4.8e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)Q60775 1.9e-5 4.0e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P97360 5.3e-4 4.7e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 0.0e+0 4.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 0.0e+0 4.1e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 0.0e+0 4.7e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P41212 0.0e+0 4.5e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P41212 0.0e+0 4.8e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 6.9e-14 4.2e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 0.0e+0 3.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)P78545 4.2e-2 8.7e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 4.2e-2 3.2e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 4.0e-2 3.1e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)P78545 2.3e-2 1.8e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)Q9UKW6 4.9e-2 3.6e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P41212 5.0e-2 3.7e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor)Q99607 0.0e+0 3.9e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor)Q99607 0.0e+0 4.1e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 7.5e-8 4.0e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 5.1e-8 3.9e-1Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q9JHC9 0.0e+0 4.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)Q3UPW2 0.0e+0 2.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)Q3UPW2 0.0e+0 3.1e-3Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-5 (E74-like factor 5)Q8VDK3 0.0e+0 1.3e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q9JHC9 0.0e+0 3.0e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)Q3UPW2 0.0e+0 4.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)Q3UPW2 0.0e+0 3.0e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-5 (E74-like factor 5)Q8VDK3 0.0e+0 3.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q9JHC9 0.0e+0 1.6e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)Q3UPW2 0.0e+0 5.7e-4Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-5 (E74-like factor 5)Q8VDK3 0.0e+0 1.5e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 0.0e+0 5.4e-8Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 0.0e+0 7.6e-3Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 0.0e+0 3.2e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 0.0e+0 4.4e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)P78545 0.0e+0 1.7e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor)Q99607 0.0e+0 3.3e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)Q9UKW6 0.0e+0 3.4e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P41212 0.0e+0 1.1e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-1 (E74-like factor 1)P32519 0.0e+0 3.4e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Q15723 0.0e+0 2.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1)P78545 0.0e+0 3.2e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)Q9UKW6 0.0e+0 1.5e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)P41212 0.0e+0 1.2e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111K4J19 / 0 / 19
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