EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Serine incorporator 3 (Tumor differentially expressed protein 1)SERINC3 DIFF33 TDE1 SBBI99Q1353014
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3Q0795514
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29)PPP2R5C KIAA0044Q1336214
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC
Signal recognition particle 54 kDa protein (SRP54)SRP54P6101114
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)SNRPF PBSCFP6230614
Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8)SLC6A8P4802914
Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Prosolin) (Protein Pr22) (pp17)STMN1 C1orf215 LAP18 OP18P1694914
Superoxide dismutase [Cu-Zn] (EC (Superoxide dismutase 1) (hSod1)SOD1P0044114
Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8)TCEAL8Q8IYN214
Transcription elongation factor B polypeptide 2 (Elongin 18 kDa subunit) (Elongin-B) (EloB) (RNA polymerase II transcription factor SIII subunit B) (SIII p18)TCEB2Q1537014
Transcription factor IIIA (TFIIIA)GTF3AQ9266414
Transcription factor jun-DJUNDP1753514
Translation machinery-associated protein 7 (Coiled-coil domain-containing protein 72)TMA7 CCDC72 HSPC016 HSPC330Q9Y2S614
TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin)TRIOBP KIAA1662 TARA HRIHFB2122Q9H2D614
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)TPM1 C15orf13 TMSAP0949314
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')SNRPB2P0857914
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)ATG12 APG12 APG12LO9481714
Uncharacterized protein KIAA2013KIAA2013Q8IYS214
UPF0585 protein C16orf13C16orf13 JFP2Q96S1914
14-3-3 protein epsilon (14-3-3E)YWHAEP6225813
26S protease regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)PSMC6 SUG2P6233313
28S ribosomal protein S11, mitochondrial (MRP-S11) (S11mt) (Cervical cancer proto-oncogene 2 protein) (HCC-2)MRPS11 RPMS11 HCC2P8291213
28S ribosomal protein S21, mitochondrial (MRP-S21) (S21mt)MRPS21 RPMS21 MDS016P8292113
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC PDK1O1553013
39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9)MRPL9Q9BYD213
40S ribosomal protein S28RPS28P6285713
40S ribosomal protein S3RPS3 OK/SW-cl.26P2339613
40S ribosomal protein S4, X isoform (SCR10) (Single copy abundant mRNA protein)RPS4X CCG2 RPS4 SCARP6270113
60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2)TROVE2 RO60 SSA2P1015513
60S ribosomal protein L10 (Laminin receptor homolog) (Protein QM) (Tumor suppressor QM)RPL10 DXS648E QMP2763513
60S ribosomal protein L28RPL28P4677913
60S ribosomal protein L29 (Cell surface heparin-binding protein HIP)RPL29P4791413
60S ribosomal protein L6 (Neoplasm-related protein C140) (Tax-responsive enhancer element-binding protein 107) (TaxREB107)RPL6 TXREB1Q0287813
A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen)AKAP12 AKAP250Q0295213
A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta)AKAP7 AKAP15 AKAP18O4368713
Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein)FIBPO4342713
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)ARPC3 ARC21O1514513
Adenylate kinase 4, mitochondrial (AK 4) (EC (EC (Adenylate kinase 3-like) (GTP:AMP phosphotransferase AK4)AK4 AK3 AK3L1P2714413
ADP-ribosylation factor 4ARF4 ARF2P1808513
ADP-ribosylation factor-like protein 1ARL1P4061613
ADP-ribosylation factor-like protein 17 (ADP-ribosylation factor 7 variant)ARL17A ARL17P1; ARL17B ARF1P2 ARL17A PRO2667Q8IVW113
ADP-ribosylation factor-like protein 5AARL5A ARFLP5 ARL5Q9Y68913
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)SNCA NACP PARK1P3784013
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 (AGAP-4) (Centaurin-gamma-like family member 1)AGAP4 CTGLF1 MRIP2Q96P6413
Aspartate aminotransferase, cytoplasmic (cAspAT) (EC (EC (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A)GOT1P1717413
ATP synthase subunit O, mitochondrial (Oligomycin sensitivity conferral protein) (OSCP)ATP5O ATPOP4804713
ATP-dependent RNA helicase DDX18 (EC (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)DDX18Q9NVP113
Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147)BSG UNQ6505/PRO21383P3561313
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)BAIAP2Q9UQB813
Calcium-regulated heat stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24)CARHSP1Q9Y2V213
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2)CTDSP2 NIF2 OS4 SCP2O1459513
Carnitine O-acetyltransferase (Carnitine acetylase) (EC (Carnitine acetyltransferase) (CAT) (CrAT)CRAT CAT1P4315513
Casein kinase II subunit alpha (CK II alpha) (EC CK2A1P6840013
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)CNOT1 CDC39 KIAA1007 NOT1 AD-005A5YKK613
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)CD63 MLA1 TSPAN30P0896213
Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)CHMP3 CGI149 NEDF VPS24 CGI-149Q9Y3E713
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)CHD4Q1483913
Coatomer subunit beta (Beta-coat protein) (Beta-COP)COPB1 COPB MSTP026P5361813
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)GPS1 COPS1 CSN1Q1309813
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (DNA-binding protein TAXREB67) (Tax-responsive enhancer element-binding protein 67) (TaxREB67)ATF4 CREB2 TXREBP1884813
Cyclin-A2 (Cyclin-A)CCNA2 CCN1 CCNAP2024813
Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1)COX6B1 COX6BP1485413
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)DYNC1LI2 DNCLI2 LIC2O4323713
D-dopachrome decarboxylase (EC (D-dopachrome tautomerase) (Phenylpyruvate tautomerase II)DDTP3004613
Diablo homolog, mitochondrial (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac)DIABLO SMACQ9NR2813
DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1)MSH3 DUC1 DUGP2058513
DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2)RAD51C RAD51L2O4350213
Dolichol-phosphate mannosyltransferase (EC (Dolichol-phosphate mannose synthase) (DPM synthase) (Dolichyl-phosphate beta-D-mannosyltransferase) (Mannose-P-dolichol synthase) (MPD synthase)DPM1O6076213
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)DCTN1Q1420313
Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22)DCTN3 DCTN22O7593513
EEF1G protein (Eukaryotic translation elongation factor 1 gamma) (Eukaryotic translation elongation factor 1 gamma, isoform CRA_c) (GIG35)EEF1G hCG_2039458Q53YD713
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog)HSP90B1 GRP94 TRA1P1462513
Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF-2-gamma X) (eIF-2gX)EIF2S3 EIF2GP4109113
Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) (eIF-3-zeta) (eIF3 p66)EIF3D EIF3S7O1537113
Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48)EIF3E EIF3S6 INT6P6022813
Exosome complex component CSL4 (Exosome component 1)EXOSC1 CSL4 CGI-108Q9Y3B213
F-box only protein 7FBXO7 FBX7Q9Y3I113
FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)FARP1 CDEP PLEKHC2Q9Y4F113
Fibulin-1 (FIBL-1)FBLN1 PP213P2314213
Fructose-bisphosphate aldolase C (EC (Brain-type aldolase)ALDOC ALDCP0997213
Glioma tumor suppressor candidate region gene 2 protein (p60)GLTSCR2Q9NZM513
Glutathione S-transferase Mu 1 (EC (GST HB subunit 4) (GST class-mu 1) (GSTM1-1) (GSTM1a-1a) (GSTM1b-1b) (GTH4)GSTM1 GST1P0948813
Glutathione S-transferase omega-1 (GSTO-1) (EC (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC (S-(Phenacyl)glutathione reductase) (SPG-R)GSTO1 GSTTLP28P7841713
Glutathione synthetase (GSH synthetase) (GSH-S) (EC (Glutathione synthase)GSSP4863713
Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7)ACBD3 GCP60 GOCAP1 GOLPH1Q9H3P713
GTPase HRas (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]HRAS HRAS1P0111213
H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)CLCN7P5179813
Heat shock 70kDa protein 8 isoform 2 variant (Fragment)0Q53HF213
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]HNRNPH1 HNRPH HNRPH1P3194313
Heterogeneous nuclear ribonucleoprotein R (hnRNP R)HNRNPR HNRPRO4339013
HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) (RCF1 homolog A) (RCF1a)HIGD1A HIG1 HSPC010Q9Y24113
High mobility group nucleosome-binding domain-containing protein 4 (Non-histone chromosomal protein HMG-17-like 3) (Non-histone chromosomal protein)HMGN4 HMG17L3 NHCO0047913
Histone-arginine methyltransferase CARM1 (EC 2.1.1.-) (EC (Coactivator-associated arginine methyltransferase 1) (Protein arginine N-methyltransferase 4)CARM1 PRMT4Q86X5513
Homeobox protein Hox-B7 (Homeobox protein HHO.C1) (Homeobox protein Hox-2C)HOXB7 HOX2CP0962913
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)HIF1A BHLHE78 MOP1 PASD8Q1666513
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (NifU-like N-terminal domain-containing protein) (NifU-like protein)ISCU NIFUNQ9H1K113
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)IDH3AP5021313
L-lactate dehydrogenase B chain (LDH-B) (EC (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46)LDHBP0719513
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