This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (C-JUN leucine zipper interactive protein JZA-3) (Thymine-DNA glycosylase)P56581 0.0e+0 1.5e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (C-JUN leucine zipper interactive protein JZA-3) (Thymine-DNA glycosylase)P56581 4.0e-14 2.7e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (cDNA FLJ50939, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-))B4E127 0.0e+0 3.2e-2Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA.
Blood. 2007 Oct 1;110(7):2440-8. Epub 2007 May 29.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (cDNA FLJ50939, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-))B4E127 2.8e-6 4.5e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG)Q13569 0.0e+0 4.3e-1Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.
J Cell Mol Med. 2010 Jun;14(6B):1605-18. doi: 10.1111/j.1582-4934.2009.00860.x. Epub 2009 Jul 24.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (cDNA FLJ50939, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-))B4E127 0.0e+0 3.9e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (cDNA FLJ50939, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-))B4E127 0.0e+0 3.9e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		COG366311 / 0 / 11
T:G mismatch thymine glycosylaseQ99NG8 0.0e+0 1.8e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		COG366311 / 0 / 11
T:G mismatch thymine glycosylaseQ99NG8 0.0e+0 2.7e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (C-JUN leucine zipper interactive protein JZA-3) (Thymine-DNA glycosylase)P56581 0.0e+0 4.8e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (C-JUN leucine zipper interactive protein JZA-3) (Thymine-DNA glycosylase)P56581 0.0e+0 4.3e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG)Q13569 0.0e+0 4.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG)Q13569 0.0e+0 3.0e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG)Q13569 0.0e+0 2.4e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		COG366311 / 0 / 11
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG)Q13569 0.0e+0 3.1e-13Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		COG366311 / 0 / 11
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