EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (BAG6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)BAG6 BAT3 G3P4637913
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)LASP1 MLN50Q1484713
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)PPFIBP1 KIAA1230Q86W9213
Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B)SSBP0545513
Metaxin-1 (Mitochondrial outer membrane import complex protein 1)MTX1 MTX MTXNQ1350513
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)MRI1 MRDI UNQ6390/PRO21135Q9BV2013
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)MAPK1 ERK2 PRKM1 PRKM2P2848213
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)PDE4DIP CMYA2 KIAA0454 KIAA0477 MMGLQ5VU4313
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3NDUFAF3 C3orf60Q9BU6113
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a)NDUFA7O9518213
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)NEDD8Q1584313
Nipped-B-like protein (Delangin) (SCC2 homolog)NIPBL IDN3Q6KC7913
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)NFIXQ1493813
Nucleolar protein 56 (Nucleolar protein 5A)NOP56 NOL5AO0056713
OCIA domain-containing protein 2 (Ovarian carcinoma immunoreactive antigen-like protein)OCIAD2Q56VL313
Pericentriolar material 1 protein (PCM-1) (hPCM-1)PCM1Q1515413
Periphilin-1 (Gastric cancer antigen Ga50)PPHLN1 HSPC206 HSPC232Q8NEY813
Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)PHKBQ9310013
Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)PNN DRS MEMAQ9H30713
Plakophilin-4 (p0071)PKP4Q9956913
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)PTBP3 ROD1O9575813
Pre-mRNA branch site protein p14 (SF3b 14 kDa subunit)SF3B14 CGI-110 HSPC175 HT006Q9Y3B413
Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1)PA2G4 EBP1Q9UQ8013
Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)PSME3P6128913
Protein G8C6orf48 G8Q9UBA613
Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11)S100A10 ANX2LG CAL1L CLP11P6090313
Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)S100A4 CAPL MTS1P2644713
Protein transport protein Sec23B (SEC23-related protein B)SEC23BQ1543713
Ras-related protein Rab-5C (L1880) (RAB5L)RAB5C RABLP5114813
Receptor tyrosine-protein kinase erbB-2 (EC (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)ERBB2 HER2 MLN19 NEU NGLP0462613
Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-)RNASEKQ6P5S713
RNA demethylase ALKBH5 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5)ALKBH5 ABH5 OFOXD1Q6P6C213
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen)FBL FIB1 FLRNP2208713
S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC (Methionine adenosyltransferase 2) (MAT 2) (Methionine adenosyltransferase II) (MAT-II)MAT2A AMS2 MATA2P3115313
Selenoprotein W (SelW)SEPW1 SELWP6330213
Serine/threonine-protein phosphatase 2A activator (EC (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B')PPP2R4 PTPAQ1525713
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC (Protein phosphatase 1C catalytic subunit)PPP1CCP3687313
Signal recognition particle 14 kDa protein (SRP14) (18 kDa Alu RNA-binding protein)SRP14P3710813
Sp110 nuclear body protein (Interferon-induced protein 41/75) (Speckled 110 kDa) (Transcriptional coactivator Sp110)SP110Q9HB5813
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)HSPA9 GRP75 HSPA9B mt-HSP70P3864613
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS) (CII-4) (QPs3) (Succinate dehydrogenase complex subunit D) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit) (Succinate-ubiquinone reductase membrane anchor subunit)SDHD SDH4O1452113
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)SMARCC2 BAF170Q8TAQ213
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)TCP1 CCT1 CCTAP1798713
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)TAF15 RBP56 TAF2NQ9280413
Tax1-binding protein 1 (TRAF6-binding protein)TAX1BP1 T6BP PRO0105Q86VP113
TP53-target gene 3 protein (TP53-inducible gene 3 protein)TP53TG3 TP53TG3A; TP53TG3B; TP53TG3C; TP53TG3DQ9ULZ013
Transmembrane protein 160TMEM160Q9NX0013
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)UBQLN1 DA41 PLIC1Q9UMX013
Ubiquitin-conjugating enzyme E2 B (EC (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B)UBE2B RAD6BP6314613
Ubiquitin-conjugating enzyme E2 L3 (EC (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)UBE2L3 UBCE7 UBCH7P6803613
Uncharacterized protein C19orf48 (Multidrug resistance-related protein)C19orf48Q6RUI813
Uncharacterized protein C1orf43 (Hepatitis C virus NS5A-transactivated protein 4) (HCV NS5A-transactivated protein 4) (Protein NICE-3) (S863-3)C1orf43 NICE3 NS5ATP4 HSPC012Q9BWL313
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)RAD23BP5472713
Vacuolar protein sorting-associated protein 41 homolog (S53)VPS41P4975413
Vesicle-fusing ATPase (EC (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)NSFP4645913
Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3)VDAC3Q9Y27713
WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)WSB2Q9NYS713
YTH domain-containing protein 1 (Putative splicing factor YT521)YTHDC1 KIAA1966 YT521Q96MU713
40S ribosomal protein S15 (RIG protein)RPS15 RIGP6284112
60S ribosomal protein L19RPL19P8409812
60S ribosomal protein L5RPL5 MSTP030P4677712
A-kinase-interacting protein 1 (Breast cancer-associated gene 3 protein) (PKA-interacting protein) (Proline-rich protein BCA3)AKIP1 BCA3 C11orf17Q9NQ3112
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)ABI2 ARGBPIAQ9NYB912
Acetyl-CoA carboxylase 1 (ACC1) (EC (ACC-alpha) [Includes: Biotin carboxylase (EC]ACACA ACAC ACC1 ACCAQ1308512
Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (LANP) (Mapmodulin) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Putative HLA-DR-associated protein I) (PHAPI)ANP32A C15orf1 LANP MAPM PHAP1P3968712
Alcohol dehydrogenase [NADP(+)] (EC (Aldehyde reductase) (Aldo-keto reductase family 1 member A1)AKR1A1 ALDR1 ALRP1455012
Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC (Aldehyde dehydrogenase family 7 member A1) (EC (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)ALDH7A1 ATQ1P4941912
Amino-terminal enhancer of split (Amino enhancer of split) (Gp130-associated protein GAM) (Protein ESP1) (Protein GRG)AES GRGQ0811712
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)AIMP2 JTV1 PRO0992Q1315512
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)ANAPC1 TSG24Q9H1A412
Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16)ANKRD17 GTAR KIAA0697O7517912
AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 subunit sigma-1A) (Adaptor protein complex AP-1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin)AP1S1 AP19 CLAPS1P6196612
ATP synthase F(0) complex subunit C3, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P3) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C3) (ATPase protein 9) (ATPase subunit c)ATP5G3P4820112
ATP synthase subunit f, mitochondrialATP5J2 ATP5JLP5613412
Basic salivary proline-rich protein 1 (Salivary proline-rich protein) [Cleaved into: Proline-rich peptide II-2; Basic peptide IB-6; Peptide P-H]PRB1P0428012
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3BNIP3 NIP3Q1298312
Breast cancer metastasis-suppressor 1BRMS1Q9HCU912
Bromodomain-containing protein 4 (Protein HUNK1)BRD4 HUNK1O6088512
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))CTNND1 KIAA0384O6071612
Cathepsin L1 (EC (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]CTSL CTSL1P0771112
Caveolin-1CAV1 CAVQ0313512
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)CHAF1A CAF CAF1P150Q1311112
Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77)CSTF3Q1299612
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)COPB2P3560612
Coiled-coil domain-containing protein 90B, mitochondrialCCDC90B CUA003 MDS011 MDS025Q9GZT612
Cold shock domain-containing protein E1 (N-ras upstream gene protein) (Protein UNR)CSDE1 D1S155E KIAA0885 NRU UNRO7553412
COMM domain-containing protein 4COMMD4Q9H0A812
COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (hCOP9) (JAB1-containing signalosome subunit 8)COPS8 CSN8Q9962712
Cyclin-D1-binding protein 1 (Grap2 and cyclin-D-interacting protein) (Human homolog of Maid)CCNDBP1 DIP1 GCIP HHMO9527312
Cyclin-dependent kinase 2 (EC (Cell division protein kinase 2) (p33 protein kinase)CDK2 CDKN2P2494112
Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL)COX7A2 COX7ALP1440612
Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain)DYNC2LI1 D2LIC LIC3 CGI-60Q8TCX112
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)ECH1Q1301112
Deoxycytidylate deaminase (EC (dCMP deaminase)DCTDP3232112
Disabled homolog 2 (DOC-2) (Differentially-expressed protein 2)DAB2 DOC2P9808212
DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19)POLR1DQ9Y2S012
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)POLR2LP6287512
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)DNAJA1 DNAJ2 HDJ2 HSJ2 HSPF4P3168912
Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha)DRAP1Q1491912
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