This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]P20827 3.1e-10 3.6e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG4111FMJ22 / 0 / 22
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)P52803 1.9e-10 3.6e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG4111FMJ22 / 0 / 22
Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)P52799 3.0e-8 4.0e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		ENOG4111FMJ22 / 0 / 22
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)P52798 0.0e+0 5.1e-3Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		ENOG4111FMJ22 / 0 / 22
Ephrin B3 (Predicted) (Protein Efnb3)G3V7D4 0.0e+0 1.5e-1Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		ENOG4111FMJ22 / 0 / 22
Ephrin B3 (Predicted) (Protein Efnb3)G3V7D4 0.0e+0 9.8e-2Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Cancer Res. 2010 Feb 15;70(4):1668-78. doi: 10.1158/0008-5472.CAN-09-2470. Epub 2010 Feb 2.		ENOG4111FMJ22 / 0 / 22
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)O08543 0.0e+0 4.0e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		ENOG4111FMJ22 / 0 / 22
Ephrin-B2 (ELF-2) (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)P52800 2.2e-6 4.2e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111FMJ22 / 0 / 22
Ephrin-B2 (ELF-2) (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)P52800 4.4e-7 3.4e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		ENOG4111FMJ22 / 0 / 22
Ephrin-B3 (EPH-related receptor transmembrane ligand ELK-L3) (EPH-related receptor tyrosine kinase ligand 8) (LERK-8)Q15768 0.0e+0 3.2e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.		ENOG4111FMJ22 / 0 / 22
Ephrin-B3 (EPH-related receptor transmembrane ligand ELK-L3) (EPH-related receptor tyrosine kinase ligand 8) (LERK-8)Q15768 0.0e+0 3.1e-1RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.
BMC Cancer. 2012 Jan 17;12:22. doi: 10.1186/1471-2407-12-22.		ENOG4111FMJ22 / 0 / 22
Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)P52799 2.1e-8 4.9e-1Identifying mRNA, microRNA and protein profiles of melanoma exosomes.
PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.		ENOG4111FMJ22 / 0 / 22
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)P52798 4.2e-2 7.2e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111FMJ22 / 0 / 22
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)P52798 3.7e-2 7.0e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111FMJ22 / 0 / 22
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)P52803 4.0e-2 8.0e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111FMJ22 / 0 / 22
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2)P98172 4.5e-2 9.6e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111FMJ22 / 0 / 22
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)P52798 4.5e-2 3.4e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111FMJ22 / 0 / 22
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2)P98172 2.6e-2 2.1e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		ENOG4111FMJ22 / 0 / 22
Ephrin-A2 (EPH-related receptor tyrosine kinase ligand 6) (LERK-6) (HEK7 ligand) (HEK7-L)O43921 1.7e-14 4.9e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		ENOG4111FMJ22 / 0 / 22
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)P52798 0.0e+0 3.9e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		ENOG4111FMJ22 / 0 / 22
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)P52798 0.0e+0 3.8e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		ENOG4111FMJ22 / 0 / 22
Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)P52799 0.0e+0 4.9e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		ENOG4111FMJ22 / 0 / 22
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)O08543 0.0e+0 2.0e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111FMJ22 / 0 / 22
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)O08543 0.0e+0 1.1e-2Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111FMJ22 / 0 / 22
Ephrin-B2 (ELF-2) (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)P52800 0.0e+0 4.0e-1Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.
J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.		ENOG4111FMJ22 / 0 / 22
Ephrin-A3 (EFL-2) (EHK1 ligand) (EHK1-L) (EPH-related receptor tyrosine kinase ligand 3) (LERK-3)P52797 0.0e+0 5.1e-10Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG4111FMJ22 / 0 / 22
Ephrin-A3 (EFL-2) (EHK1 ligand) (EHK1-L) (EPH-related receptor tyrosine kinase ligand 3) (LERK-3)P52797 0.0e+0 1.5e-3Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		ENOG4111FMJ22 / 0 / 22
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]P20827 0.0e+0 1.9e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111FMJ22 / 0 / 22
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]P20827 0.0e+0 1.6e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		ENOG4111FMJ22 / 0 / 22
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