EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)EPS15L1 EPS15RQ9UBC27
ERI1 exoribonuclease 3 (EC 3.1.-.-) (Prion interactor 1) (Prion protein-interacting protein)ERI3 PINT1 PRNPIP PRNPIP1O434147
Ester hydrolase C11orf54 (EC 3.1.-.-)C11orf54 LP4947 PTD012Q9H0W97
ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1)ELK4 SAP1P283247
ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F) (Polyomavirus enhancer activator 3 homolog) (Protein PEA3)ETV4 E1AF PEA3P432687
Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein)EIF2AK4 GCN2 KIAA1338Q9P2K87
Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin)EIF2D HCA56 LGTNP412147
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (mRNA cap-binding protein type 3)EIF4E2 EIF4EL3O605737
Eukaryotic translation initiation factor 5A-1-like (eIF-5A-1-like) (eIF-5A1-like) (Eukaryotic initiation factor 5A isoform 1-like)EIF5AL1Q6IS147
Exocyst complex component 1 (Exocyst complex component Sec3)EXOC1 SEC3 SEC3L1 BM-012Q9NV707
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)XPO1 CRM1O149807
Eyes absent homolog 3 (EC 3.1.3.48)EYA3Q995047
F-actin-capping protein subunit alpha-1 (CapZ alpha-1)CAPZA1P529077
F-box only protein 18 (EC 3.6.4.12) (F-box DNA helicase 1)FBXO18 FBH1 FBX18Q8NFZ07
F-box only protein 50 (NCC receptor protein 1 homolog) (NCCRP-1) (Non-specific cytotoxic cell receptor protein 1 homolog)NCCRP1 FBXO50Q6ZVX77
F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked)TBL1X TBL1O609077
F-box/LRR-repeat protein 15 (F-box only protein 37)FBXL15 FBXO37Q9H4697
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)SUPT16H FACT140 FACTP140Q9Y5B97
FAS-associated factor 2 (Protein ETEA) (UBX domain-containing protein 3B) (UBX domain-containing protein 8)FAF2 ETEA KIAA0887 UBXD8 UBXN3BQ96CS37
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]FGAP026717
Fibroblast growth factor 22 (FGF-22)FGF22 UNQ2500/PRO5800Q9HCT07
Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14)FOXC2 FKHL14 MFH1Q999587
Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells)FOXM1 FKHL16 HFH11 MPP2 WINQ080507
Forkhead box protein N2 (Human T-cell leukemia virus enhancer factor)FOXN2 HTLFP323147
Fos-related antigen 1 (FRA-1)FOSL1 FRA1P154077
FXYD domain-containing ion transport regulator 3 (Chloride conductance inducer protein Mat-8) (Mammary tumor 8 kDa protein) (Phospholemman-like)FXYD3 MAT8 PLMLQ148027
G protein pathway suppressor 2 (GPS-2)GPS2Q132277
Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced gene 1 protein)LGALS7 PIG1; LGALS7BP479297
Gamma-glutamylcyclotransferase (EC 2.3.2.4) (Cytochrome c-releasing factor 21)GGCT C7orf24 CRF21O752237
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)IFI16 IFNGIP1Q166667
GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)TSTA3 SDR4E1Q136307
GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)GMDSO605477
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)GSNP063967
Gem-associated protein 6 (Gemin-6) (SIP2)GEMIN6Q8WXD57
General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon)GTF3C5 CDABP0017Q9Y5Q87
General transcription factor IIF subunit 2 (EC 3.6.4.12) (ATP-dependent helicase GTF2F2) (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30)GTF2F2 RAP30P139847
General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit)GTF2H5 C6orf175 TTDAQ6ZYL47
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)NR3C1 GRLP041507
Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)GCLC GLCL GLCLCP485067
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 1) (Glutamine:fructose-6-phosphate amidotransferase 1) (GFAT 1) (GFAT1) (Hexosephosphate aminotransferase 1)GFPT1 GFAT GFPTQ062107
Glutathione S-transferase C-terminal domain-containing proteinGSTCDQ8NEC77
Glycogen phosphorylase, liver form (EC 2.4.1.1)PYGLP067377
Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186)GYG2O154887
Glycophorin-EGYPE GPEP154217
Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A)LARGE KIAA0609 LARGE1O954617
Glyoxalase domain-containing protein 4GLOD4 C17orf25 CGI-150 My027Q9HC387
Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2)GLIPR2 C9orf19 GAPR1Q9H4G47
Golgin subfamily A member 8A (88 kDa Golgi matrix protein) (GM88) (GM88 autoantigen)GOLGA8AA7E2F47
GPN-loop GTPase 2 (ATP-binding domain 1 family member B)GPN2 ATPBD1B UNQ5828/PRO19647Q9H9Y47
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (GM-CSF-R-alpha) (GMCSFR-alpha) (GMR-alpha) (CDw116) (CD antigen CD116)CSF2RA CSF2R CSF2RYP155097
Growth arrest-specific protein 8 (GAS-8) (Growth arrest-specific protein 11) (GAS-11)GAS8 GAS11O959957
Growth factor receptor-bound protein 2 (Growth factor receptor-bound protein 2, isoform CRA_a) (cDNA, FLJ96637, Homo sapiens growth factor receptor-bound protein 2 (GRB2), mRNA)GRB2 hCG_27179B0LPF37
Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasing peptide receptor) (GHRP) (Ghrelin receptor)GHSRQ928477
GTP-binding protein SAR1a (COPII-associated small GTPase)SAR1A SAR1 SARA SARA1Q9NR317
GTP-binding protein SAR1b (GTP-binding protein B) (GTBPB)SAR1B SARA2 SARBQ9Y6B67
GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (Adenylate kinase 3 alpha-like 1)AK3 AK3L1 AK6 AKL3LQ9UIJ77
GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]KRAS KRAS2 RASK2P011167
Guanine nucleotide exchange factor VAV2 (VAV-2)VAV2P527357
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)GNAS GNAS1 GSPP630927
H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1)GAR1 NOLA1Q9NY127
Hamartin (Tuberous sclerosis 1 protein)TSC1 KIAA0243 TSCQ925747
Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP)SKIV2L DDX13 SKI2W SKIV2 WQ154777
Hematopoietic cell signal transducer (DNAX-activation protein 10) (Membrane protein DAP10) (Transmembrane adapter protein KAP10)HCST DAP10 KAP10 PIK3AP UNQ587/PRO1157Q9UBK57
Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75)HCLS1 HS1P143177
Heme transporter HRG1 (Heme-responsive gene 1 protein homolog) (HRG-1) (hHRG-1) (Solute carrier family 48 member 1)SLC48A1 HRG1Q6P1K17
Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL)HEBP2 C6orf34 SOULQ9Y5Z47
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)HNRNPL HNRPL P/OKcl.14P148667
Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) (Stromal RNA-regulating factor)HNRNPLL HNRPLL SRRF BLOCK24Q8WVV97
HIG1 domain family member 2A, mitochondrial (RCF1 homolog B) (RCF1b)HIGD2AQ9BW727
Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)HARS HRSP120817
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)HDAC5 KIAA0600Q9UQL67
Histone H2B type 2-FHIST2H2BFQ5QNW67
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)CENPAP494507
Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.43) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (NSD2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) (WHSC1)WHSC1 KIAA1090 MMSET NSD2 TRX5O960287
HLA class I histocompatibility antigen, alpha chain G (HLA G antigen) (MHC class I antigen G)HLA-G HLA-6.0 HLAGP176937
HRAS-like suppressor 3 (HRSL3) (EC 3.1.1.32) (EC 3.1.1.4) (Adipose-specific phospholipase A2) (AdPLA) (Group XVI phospholipase A1/A2) (H-rev 107 protein homolog) (HRAS-like suppressor 1) (HREV107-1) (HREV107-3) (Renal carcinoma antigen NY-REN-65)PLA2G16 HRASLS3 HREV107P538167
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)HADH HAD HADHSC SCHADQ168367
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)HMGCS1 HMGCSQ015817
Immunoglobulin superfamily containing leucine-rich repeat proteinISLR UNQ189/PRO215O144987
Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2)ING2 ING1LQ9H1607
Inhibitor of growth protein 3 (p47ING3)ING3 HSPC301Q9NXR87
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]IGF1RP080697
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)IGF2BP1 CRDBP VICKZ1 ZBP1Q9NZI87
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)IGF2BP3 IMP3 KOC1 VICKZ3O004257
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)TMEM219Q86XT97
Insulin-like growth factor-binding protein 6 (IBP-6) (IGF-binding protein 6) (IGFBP-6)IGFBP6 IBP6P245927
Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)CPSF3L INTS11 RC68Q5TA457
Integrator complex subunit 4 (Int4)INTS4 MSTP093Q96HW77
Integrator complex subunit 5 (Int5)INTS5 KIAA1698Q6P9B97
Intercellular adhesion molecule 4 (ICAM-4) (Landsteiner-Wiener blood group glycoprotein) (LW blood group protein) (CD antigen CD242)ICAM4 LWQ147737
Interferon alpha-inducible protein 27-like protein 1 (Interferon-stimulated gene 12c protein) (ISG12(c))IFI27L1 FAM14BQ96BM07
Interferon gamma receptor 2 (IFN-gamma receptor 2) (IFN-gamma-R2) (Interferon gamma receptor accessory factor 1) (AF-1) (Interferon gamma transducer 1)IFNGR2 IFNGT1P384847
Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa)ILF2 NF45 PRO3063Q129057
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)IRAK1 IRAKP516177
Interleukin-1 receptor-like 1 (Protein ST2)IL1RL1 DER4 ST2 T1Q016387
Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69)ICA1Q050847
Isochorismatase domain-containing protein 2, mitochondrialISOC2Q96AB37
IST1 homolog (hIST1) (Putative MAPK-activating protein PM28)IST1 KIAA0174P539907
KazrinKAZN KAZ KIAA1026 HRIHFB2003Q674X77
Kelch domain-containing protein 10KLHDC10 KIAA0265Q6PID87
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