EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin)DCTN2 DCTN50Q1356112
Estradiol 17-beta-dehydrogenase 12 (EC (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (EC 1.3.1.-)HSD17B12Q53GQ012
Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit)EIF3H EIF3S3O1537212
Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2)EIF4EBP2Q1354212
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein)EIF4H KIAA0038 WBSCR1 WSCR1Q1505612
F-actin-capping protein subunit beta (CapZ beta)CAPZBP4775612
F-box only protein 9 (Cross-immune reaction antigen 1) (Renal carcinoma antigen NY-REN-57)FBXO9 FBX9 VCIA1Q9UK9712
Focal adhesion kinase 1 (FADK 1) (EC (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)PTK2 FAK FAK1Q0539712
G-rich sequence factor 1 (GRSF-1)GRSF1Q1284912
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)LGALS8O0021412
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)GABARAPL1 GEC1Q9H0R812
Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC
Glycogenin-1 (GN-1) (GN1) (EC GYGP4697612
Golgin subfamily A member 6-like protein 1GOLGA6L1I3L08712
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100)GAB2 KIAA0571Q9UQC212
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10GNG10 GNGT10P5015112
H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)DKC1 NOLA4O6083212
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)HMGA1 HMGIYP1709612
HIRA-interacting protein 3HIRIP3Q9BW7112
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)KMT2C HALR KIAA1506 MLL3Q8NEZ412
HLA class I histocompatibility antigen, alpha chain E (MHC class I antigen E)HLA-E HLA-6.2 HLAEP1374712
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)IPO7 RANBP7O9537312
Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)MCL1 BCL2L3Q0782012
Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC (Inositol hexaphosphate kinase 1)IP6K1 IHPK1 KIAA0263Q9255112
Inter-alpha-trypsin inhibitor heavy chain H5 (ITI heavy chain H5) (ITI-HC5) (Inter-alpha-inhibitor heavy chain 5)ITIH5 KIAA1953 PP14776 UNQ311/PRO354Q86UX212
Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Emoctakin) (Granulocyte chemotactic protein 1) (GCP-1) (Monocyte-derived neutrophil chemotactic factor) (MDNCF) (Monocyte-derived neutrophil-activating peptide) (MONAP) (Neutrophil-activating protein 1) (NAP-1) (Protein 3-10C) (T-cell chemotactic factor) [Cleaved into: MDNCF-a (GCP/IL-8 protein IV) (IL8/NAP1 form I); Interleukin-8 ((Ala-IL-8)77) (GCP/IL-8 protein II) (IL-8(1-77)) (IL8/NAP1 form II) (MDNCF-b); IL-8(5-77); IL-8(6-77) ((Ser-IL-8)72) (GCP/IL-8 protein I) (IL8/NAP1 form III) (Lymphocyte-derived neutrophil-activating factor) (LYNAP) (MDNCF-c) (Neutrophil-activating factor) (NAF); IL-8(7-77) (GCP/IL-8 protein V) (IL8/NAP1 form IV); IL-8(8-77) (GCP/IL-8 protein VI) (IL8/NAP1 form V); IL-8(9-77) (GCP/IL-8 protein III) (IL8/NAP1 form VI)]IL8 CXCL8P1014512
Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (hIscA)ISCA1 HBLD2 GK004Q9BUE612
Isopentenyl-diphosphate Delta-isomerase 1 (EC (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1)IDI1Q1390712
Keratin-associated protein 4-11 (Keratin-associated protein 4-14) (Keratin-associated protein 4.11) (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14)KRTAP4-11 KAP4.14 KRTAP4-14 KRTAP4.11 KRTAP4.14Q9BYQ612
Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2)L3MBTL2Q969R512
Leukocyte-specific transcript 1 protein (Protein B144)LST1 B144O0045312
Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta)LAPTM4B PSEC0001Q86VI412
Melanoma-associated antigen D1 (MAGE tumor antigen CCF) (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog)MAGED1 NRAGE PP2250 PRO2292Q9Y5V312
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)MAPRE1Q1569112
Mitogen-activated protein kinase kinase kinase MLT (EC (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)MLTK ZAK HCCS4Q9NYL212
Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7)MAD2L2 MAD2B REV7Q9UI9512
Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC (AIR carboxylase) (AIRC)]PAICS ADE2 AIRC PAISP2223412
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)BIN1 AMPHLO0049912
Myotubularin-related protein 2 (EC 3.1.3.-)MTMR2 KIAA1073Q1361412
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)MARCKS MACS PRKCSLP2996612
N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)ASMTLO9567112
NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC (Malic enzyme 2)ME2P2336812
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)NDUFB8O9516912
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC (EC (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) (TYKY subunit)NDUFS8O0021712
Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein)NFIBO0071212
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)NFIC NFIP0865112
Nuclear pore complex-interacting protein family member A1 (Nuclear pore complex-interacting protein) (NPIP)NPIPA1 NPIPQ9UND312
Nucleolar protein 7 (Nucleolar protein of 27 kDa)NOL7 C6orf90 NOP27Q9UMY112
PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Tax interaction protein 2) (TIP-2)GIPC1 C19orf3 GIPC RGS19IP1O1490812
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]FKBP4 FKBP52Q0279012
Peroxiredoxin-1 (EC (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2)PRDX1 PAGA PAGB TDPX2Q0683012
Peroxiredoxin-2 (EC (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1)PRDX2 NKEFB TDPX1P3211912
PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein)PCNPQ8WW1212
Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3)SLC25A3 PHC OK/SW-cl.48Q0032512
Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha)PITPNA PITPNQ0016912
Phosphoglucomutase-like protein 5 (Aciculin) (Phosphoglucomutase-related protein) (PGM-RP)PGM5 PGMRPQ1512412
Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)PAIP1Q9H07412
Polymerase I and transcript release factor (Cavin-1)PTRF FKSG13Q6NZI212
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)PFN1P0773712
Programmed cell death protein 4 (Neoplastic transformation inhibitor protein) (Nuclear antigen H731-like) (Protein 197/15a)PDCD4 H731Q53EL612
Prostaglandin G/H synthase 2 (EC (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)PTGS2 COX2P3535412
Proteasome subunit beta type-2 (EC (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)PSMB2P4972112
Protein arginine N-methyltransferase 1 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT1) (EC (Interferon receptor 1-bound protein 4)PRMT1 HMT2 HRMT1L2 IR1B4Q9987312
Protein cornichon homolog 1 (CNIH-1) (Cornichon family AMPA receptor auxiliary protein 1) (Protein cornichon homolog) (T-cell growth-associated molecule 77) (TGAM77)CNIH1 CNIH CNIL UNQ155/PRO181O9540612
Protein CutA (Acetylcholinesterase-associated protein) (Brain acetylcholinesterase putative membrane anchor)CUTA ACHAP C6orf82O6088812
Protein DJ-1 (EC 3.4.-.-) (Oncogene DJ1) (Parkinson disease protein 7)PARK7Q9949712
Protein enabled homologENAH MENAQ8N8S712
Protein phosphatase 1 regulatory subunit 14B (Phospholipase C-beta-3 neighbouring gene protein)PPP1R14B PLCB3N PNGQ96C9012
Protein SSXT (Protein SYT) (Synovial sarcoma translocated to X chromosome protein)SS18 SSXT SYTQ1553212
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase)PCMT1P2206112
Pumilio homolog 1 (HsPUM) (Pumilio-1)PUM1 KIAA0099 PUMH1Q1467112
Puromycin-sensitive aminopeptidase (PSA) (EC (Cytosol alanyl aminopeptidase) (AAP-S)NPEPPS PSAP5578612
Ras-related protein Rab-11A (Rab-11) (YL8)RAB11A RAB11P6249112
Reactive oxygen species modulator 1 (ROS modulator 1) (Epididymis tissue protein Li 175) (Glyrichin) (Mitochondrial targeting GxxxG motif protein) (MTGM) (Protein MGR2 homolog)ROMO1 C20orf52P6060212
Recombining binding protein suppressor of hairless (CBF-1) (J kappa-recombination signal-binding protein) (RBP-J kappa) (RBP-J) (RBP-JK) (Renal carcinoma antigen NY-REN-30)RBPJ IGKJRB IGKJRB1 RBPJK RBPSUHQ0633012
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)RARA NR1B1P1027612
Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1)RSL1D1 CATX11 CSIG PBK1 L12O7602112
Ribosomal protein 63, mitochondrial (hMRP63)MRP63Q9BQC612
RNA-binding protein Musashi homolog 2 (Musashi-2)MSI2Q96DH612
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)RNPS1 LDC2Q1528712
Selenide, water dikinase 1 (EC (Selenium donor protein 1) (Selenophosphate synthase 1)SEPHS1 SELD SPS SPS1P4990312
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)SRRM1 SRM160Q8IYB312
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)SRSF10 FUSIP1 FUSIP2 SFRS13A TASRO7549412
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)SRSF2 SFRS2Q0113012
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)SRSF3 SFRS3 SRP20P8410312
Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)SRSF9 SFRS9 SRP30CQ1324212
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC PPP1AP6213612
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)SNRPEP6230412
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)SNRPG PBSCGP6230812
Sodium/potassium-transporting ATPase subunit gamma (Na(+)/K(+) ATPase subunit gamma) (FXYD domain-containing ion transport regulator 2) (Sodium pump gamma chain)FXYD2 ATP1C ATP1G1P5471012
Sorbitol dehydrogenase (EC (L-iditol 2-dehydrogenase)SORDQ0079612
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)SPTBN1 SPTB2Q0108212
Speedy protein E1 (Williams-Beuren syndrome chromosomal region 19 protein)SPDYE1 WBSCR19Q8NFV512
Spliceosome RNA helicase DDX39B (EC (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein)DDX39B BAT1 UAP56Q1383812
STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)STAMBP AMSHO9563012
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57)SMARCE1 BAF57Q969G312
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)CCT2 99D8.1 CCTBP7837112
Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17) (UBX domain-containing protein 9)ASPSCR1 ASPL RCC17 TUG UBXD9 UBXN9Q9BZE912
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)TXNIP VDUP1Q9H3M712
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