EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)JAK1 JAK1A JAK1BP234589
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)LYN JTK8P079489
U2 small nuclear ribonucleoprotein A' (U2 snRNP A')SNRPA1P096619
U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10)MPHOSPH10 MPP10O005669
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)LSM1 CASMO151169
U6 snRNA-associated Sm-like protein LSm5LSM5Q9Y4Y99
UBA-like domain-containing protein 2UBALD2 FAM100BQ8IYN69
Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a]RPS27A UBA80 UBCEP1P629799
Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)UBE2E1 UBCH6P519659
Ubiquitin-conjugating enzyme E2 K (EC 6.3.2.19) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)UBE2K HIP2 LIGP610869
Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)UBA6 MOP4 UBE1L2A0AVT19
Ubiquitin-like protein 7 (Bone marrow stromal cell ubiquitin-like protein) (BMSC-UbP) (Ubiquitin-like protein SB132)UBL7 BMSCUBP SB132Q96S829
Ubiquitin-protein ligase E3C (EC 6.3.2.-) (HectH2)UBE3C KIAA0010 KIAA10Q153869
Uncharacterized protein C6orf62 (HBV X-transactivated gene 12 protein) (HBV XAg-transactivated protein 12)C6orf62 XTP12 Nbla00237Q9GZU09
Uncharacterized protein KIAA0930KIAA0930 C22orf9Q6ICG69
UPF0184 protein C9orf16C9orf16 EST00098Q9BUW79
UPF0461 protein C5orf24C5orf24Q7Z6I89
UPF0488 protein C8orf33C8orf33Q9H7E99
V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)ATP6V1C1 ATP6C ATP6D VATCP212839
V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)ATP6V0D1 ATP6D VPATPDP614219
V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F)ATP6V1F ATP6S14 VATFQ168649
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)VAMP3 SYB3Q158369
Vitamin K epoxide reductase complex subunit 1 (EC 1.1.4.1) (Vitamin K1 2,3-epoxide reductase subunit 1)VKORC1 VKOR MSTP134 MSTP576 UNQ308/PRO351Q9BQB69
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))XRCC5 G22P2P130109
Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)XPNPEP1 XPNPEPL XPNPEPL1Q9NQW79
Zinc finger MYM-type protein 2 (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein) (Zinc finger protein 198)ZMYM2 FIM RAMP ZNF198Q9UBW79
Zinc finger MYM-type protein 4 (Zinc finger protein 262)ZMYM4 KIAA0425 ZNF262Q5VZL59
Zinc finger protein 626ZNF626Q68DY19
Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein)GLIS2 NKLQ9BZE09
ZW10 interactor (ZW10-interacting protein 1) (Zwint-1)ZWINTO952299
ZZ-type zinc finger-containing protein 3ZZZ3Q8IYH59
10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10) (Early-pregnancy factor) (EPF)HSPE1P616048
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (EC 3.2.2.-) (c-Myc-responsive protein RCL)DNPH1 C6orf108 RCLO435988
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)PSMD1Q994608
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)PSMD14 POH1O004878
28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt)MRPS16 RPMS16 CGI-132Q9Y3D38
28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt)MRPS23 CGI-138 HSPC329Q9Y3D98
28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt) (bMRP-47) (bMRP47)MRPS24 HSPC335Q96EL28
28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt) (Imogen 38)MRPS31 IMOGN38Q926658
39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37) (39S ribosomal protein L2, mitochondrial) (L2mt) (MRP-L2)MRPL37 MRPL2 RPML2 HSPC235Q9BZE18
39S ribosomal protein L40, mitochondrial (L40mt) (MRP-L40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome) (Up-regulated in metastasis)MRPL40 NLVCF URIMQ9NQ508
39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41) (39S ribosomal protein L27 homolog) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog)MRPL41 BMRP MRPL27 RPML27 PIG3Q8IXM38
39S ribosomal protein L51, mitochondrial (L51mt) (MRP-L51) (bMRP-64) (bMRP64)MRPL51 MRP64 CDA09 HSPC241Q4U2R68
39S ribosomal protein L55, mitochondrial (L55mt) (MRP-L55)MRPL55 UNQ5835/PRO19675Q7Z7F78
4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase)ALDH9A1 ALDH4 ALDH7 ALDH9P491898
40S ribosomal protein S18 (Ke-3) (Ke3)RPS18 D6S218EP622698
4F2 cell-surface antigen heavy chain (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)SLC3A2 MDU1P081958
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase)MTHFSP499148
6-phosphofructokinase type C (EC 2.7.1.11) (6-phosphofructokinase, platelet type) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphofructokinase 1) (Phosphohexokinase)PFKP PFKFQ018138
60S ribosomal protein L26RPL26P612548
60S ribosomal protein L7-like 1RPL7L1Q6DKI18
7,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55) (2-hydroxy-dATP diphosphatase) (EC 3.6.1.56) (8-oxo-dGTPase) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1)NUDT1 MTH1P366398
Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)ARPC1A SOP2LQ927478
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38)AHSA1 C14orf3 HSPC322O954338
Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)NECAP1Q8NC968
Adenomatous polyposis coli protein 2 (Adenomatous polyposis coli protein-like) (APC-like)APC2 APCLO959968
ADP-ribosylation factor 6ARF6P623308
Adrenodoxin-like protein, mitochondrial (Ferredoxin-1-like protein)FDX1LQ6P4F28
AKT-interacting protein (Ft1) (Fused toes protein homolog)AKTIP FTSQ9H8T08
Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1)GPT AAT1 GPT1P242988
Aldose reductase (AR) (EC 1.1.1.21) (Aldehyde reductase) (Aldo-keto reductase family 1 member B1)AKR1B1 ALDR1P151218
Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)AGPS AAG5O001168
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)MGAT4B UNQ906/PRO1927Q9UQ538
Alpha-amylase 1 (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase 1) (Salivary alpha-amylase)AMY1A AMY1; AMY1B AMY1; AMY1C AMY1P047458
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)ACTR1A CTRN1P611638
ALS2 C-terminal-like proteinALS2CLQ60I278
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]AIMP1 EMAP2 SCYE1Q129048
Ankyrin repeat domain-containing protein 9ANKRD9Q96BM18
Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II)ANXA4 ANX4P095258
Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CBP-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha)ANXA5 ANX5 ENX2 PP4P087588
Anthrax toxin receptor 1 (Tumor endothelial marker 8)ANTXR1 ATR TEM8Q9H6X28
AP-3 complex subunit mu-1 (AP-3 adapter complex mu3A subunit) (Adapter-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin)AP3M1Q9Y2T28
AP-3 complex subunit mu-2 (Adapter-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B)AP3M2P536778
Apolipoprotein C-I (Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I]APOC1P026548
Apoptotic chromatin condensation inducer in the nucleus (Acinus)ACIN1 ACINUS KIAA0670Q9UKV38
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Development and differentiation-enhancing factor 2) (Paxillin-associated protein with ARF GAP activity 3) (PAG3) (Pyk2 C-terminus-associated protein) (PAP)ASAP2 DDEF2 KIAA0400O431508
Arginine/serine-rich coiled-coil protein 2RSRC2Q7L4I28
Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)ASS1 ASSP009668
Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein)ATXN2L A2D A2LG A2LP A2RPQ8WWM78
ATPase family AAA domain-containing protein 2 (EC 3.6.1.3) (AAA nuclear coregulator cancer-associated protein) (ANCCA)ATAD2 L16 PRO2000Q6PL188
ATPase inhibitor, mitochondrial (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)ATPIF1 ATPIQ9UII28
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)AIRE APECEDO439188
B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28)BCAP31 BAP31 DXS1357EP515728
BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)BAG1 HAPQ999338
Basic leucine zipper and W2 domain-containing protein 2BZW2 HSPC028 MSTP017Q9Y6E28
Bcl10-interacting CARD protein (BinCARD)C9orf89Q96LW78
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2BNIP2 NIP2Q129828
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)SNTB2 D16S2531E SNT2B2 SNTLQ134258
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]EPRS GLNS PARS QARS QPRS PIG32P078148
Bromodomain-containing protein 3 (RING3-like protein)BRD3 KIAA0043 RING3LQ150598
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein)KCTD13 BACURD1 PDIP1 POLDIP1 FKSG86 PP6832Q8WZ198
C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (Chemokine receptor-like 3) (CKR-L3) (DRY6) (G-protein coupled receptor 29) (GPR-CY4) (GPRCY4) (LARC receptor) (CD antigen CD196)CCR6 CKRL3 CMKBR6 GPR29 STRL22P516848
Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22)CHP1 CHPQ996538
Calcium signal-modulating cyclophilin ligand (CAML)CAMLG CAMLP490698
Calcium-binding protein 39-like (Antigen MLAA-34) (MO25beta) (Mo25-like protein)CAB39LQ9H9S48
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 3.6.3.8) (ATP-dependent Ca(2+) pump PMR1)ATP2C1 KIAA1347 PMR1L HUSSY-28P981948
Calmodulin-binding transcription activator 1CAMTA1 KIAA0833 MSTP023Q9Y6Y18
Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)]CLSTN1 CS1 KIAA0911O949858
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)CSNK2A2 CK2A2P197848
Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a)CSNK2B CK2N G5AP678708
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