EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Microtubule-associated protein 4 (MAP-4)Map4 Mtap4P275465
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2)Aldh1l2Q8K0095
Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute carrier family 25 member 11)Slc25a11Q9CR625
Mitochondrial import inner membrane translocase subunit Tim9Timm9 Tim9 Tim9a Timm9aQ9WV985
Mitochondrial import receptor subunit TOM40 homolog (Mitochondrial outer membrane protein of 35 kDa) (MOM35) (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog)Tomm40 Mom35 Tom40Q9QYA25
Mitochondrial-processing peptidase subunit alpha (EC 3.4.24.64) (Alpha-MPP) (P-55)Pmpca Inpp5eQ9DC615
Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)Mapk13 Serk4Q9Z1B75
Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)Map4k5Q8BPM25
MOB kinase activator 2 (Mob2 homolog) (Mps one binder kinase activator-like 2) (Ovary-specific MOB-like protein)Mob2 MmhQ8VI635
Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog)Trmt112Q9DCG95
Murinoglobulin-2 (MuG2)Mug2 Mug-2P286665
Muscleblind-like protein 2Mbnl2 Kiaa4072Q8C1815
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1) (SH3 domain-containing protein 9)Bin1 Amphl Sh3p9O085395
Myeloid cysteine-rich protein (Putative uncharacterized protein) (Resistin like gamma, isoform CRA_a) (Resistin-like gamma) (Resistin-like molecule gamma)Retnlg Xcp1 mCG_1038166Q8K4265
MyoferlinMyofE9Q3905
Myosin phosphatase Rho-interacting proteinMpripQ5SWZ55
Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9)Myl9 Myrl2Q9CQ195
N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2)Galk2Q68FH45
N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase)GalnsQ571E45
N-alpha-acetyltransferase 16, NatA auxiliary subunit (NMDA receptor-regulated 1-like protein) (NARG1-like protein)Naa16 Narg1l Nat2Q9DBB45
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)Ndufa10Q99LC35
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit)Ndufa2Q9CQ755
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit)Ndufa9Q9DC695
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 24 kDa subunit)Ndufv2Q9D6J65
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)Ndufs2Q91WD55
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit)Ndufs8Q8K3J15
Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2)Slc11a2 Dct1 Dmt1 Nramp2P492825
NEDD4 family-interacting protein 1 (NEDD4 WW domain-binding protein 5)Ndfip1 N4wbp5Q8R0W65
Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)Syne2Q6ZWQ05
Neuronal membrane glycoprotein M6-b (M6b)Gpm6b M6bP358035
NIF3-like protein 1Nif3l1Q9EQ805
Non-SMC condensin I complex, subunit GNcapgE9PWG65
Notchless protein homolog 1Nle1Q8VEJ45
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)Ncbp2 Cbp20Q9CQ495
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)NficP702555
Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133)Nup133Q8R0G95
Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)Nup210 Kiaa0906Q9QY815
Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein)NvlQ9DBY85
Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor)Noc2l NirQ9WV705
Nucleolar GTP-binding protein 2Gnl2Q99LH15
Nucleolar protein 11Nol11Q8BJW55
Nucleolar protein 16Nop16 D13Wsu177eQ9CPT55
Osteopontin (2AR) (Bone sialoprotein 1) (Calcium oxalate crystal growth inhibitor protein) (Early T-lymphocyte activation 1 protein) (Minopontin) (Secreted phosphoprotein 1) (SPP-1)Spp1 Eta-1 Op Spp-1P109235
Paraspeckle component 1 (Paraspeckle protein 1) (mPSP1)Pspc1 Psp1Q8R3265
Peptidyl-prolyl cis-trans isomerase FKBP10 (PPIase FKBP10) (EC 5.2.1.8) (65 kDa FK506-binding protein) (65 kDa FKBP) (FKBP-65) (FK506-binding protein 10) (FKBP-10) (Immunophilin FKBP65) (Rotamase)Fkbp10 Fkbp-rs Fkbp1-rs Fkbp6 Fkbp65 FkbprpQ615765
Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29)Ptrh2 Pth2Q8R2Y85
Peroxiredoxin-6Prdx6D3Z0Y25
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)Pik3r1P264505
Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta)Pi4k2bQ8CBQ55
Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1)Pik3r4 Vps15Q8VD655
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4)Gpx4O703255
Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2)Plscr2Q9DCW25
Phosphomannomutase 2 (PMM 2) (EC 5.4.2.8)Pmm2Q9Z2M75
Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein)PterQ608665
Piezo-type mechanosensitive ion channel component 1 (Protein FAM38A)Piezo1 Fam38aE2JF225
PininPnnO356915
Placenta-expressed transcript 1 protein (Antigen mAgK114)Plet1Q8VEN25
Plakophilin-3Pkp3Q9QY235
Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1)Serpine1 Mr1 Pai1 Planh1P227775
Platelet factor 4 (PF-4) (C-X-C motif chemokine 4)Pf4 Cxcl4 Scyb4Q9Z1265
Pleckstrin homology-like domain family A member 3 (TDAG51/Ipl homolog 1)Phlda3 Tih1Q9WV955
Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)Phldb1 Kiaa0638 Ll5aQ6PDH05
Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)Parp14 Kiaa1268Q2EMV95
Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Polyadenylate-specific ribonuclease)ParnQ8VDG35
Polyadenylate-binding protein (PABP)Pabpc4Q91YZ85
Polycomb protein EEDEedQ921E65
Polycomb protein Suz12 (Suppressor of zeste 12 protein homolog)Suz12 D11Ertd530e Kiaa0160Q80U705
Polymeric immunoglobulin receptor (PIgR) (Poly-Ig receptor) [Cleaved into: Secretory component]PigrO705705
PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)Prdm16 Kiaa1675 Mel1A2A9355
Pre-mRNA-splicing factor SYF1 (XPA-binding protein 2)Xab2 Syf1Q9DCD25
Prefoldin subunit 4Pfdn4E9Q6U45
Probable 28S rRNA (cytosine-C(5))-methyltransferaseNop2E9QN315
Probable 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120)Nop2 Nol1Q922K75
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41)Ddx41Q91VN65
Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 56)Ddx56 D11Ertd619e Noh61Q9D0R45
Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase)Dimt1 Dimt1lQ9D0D45
Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (mDTX2) (RING-type E3 ubiquitin transferase DTX2)Dtx2Q8R3P25
Probable rRNA-processing protein EBP2Ebna1bp2 Ebp2Q9D9035
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Ubiquitin specific protease 9 SSSRF-isoform)Usp9xQ4FE565
Procollagen C-endopeptidase enhancer 2 (Procollagen COOH-terminal proteinase enhancer 2) (PCPE-2) (Procollagen C-proteinase enhancer 2)Pcolce2 Pcpe2Q8R4W65
Profilin-2 (Profilin II)Pfn2Q9JJV25
Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19)Pdcd5 Tfar19P568125
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor)Pelp1 MnarQ9DBD55
Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133)Prom1 Prom Proml1O549905
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha)PccaQ91ZA35
ProsaposinPsapE9PZ005
ProsaposinPsapJ3QPG55
Prostaglandin E synthase 2 (EC 5.3.99.3) (GATE-binding factor 1) (GBF-1) (Microsomal prostaglandin E synthase 2) (mPGES-2) [Cleaved into: Prostaglandin E synthase 2 truncated form]Ptges2 Gbf1 Pges2Q8BWM05
Protein ABHD17B (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 17B) (Abhydrolase domain-containing protein 17B)Abhd17bQ7M7595
Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen homolog)Kiaa1524 Cip2aQ8BWY95
Protein CREG1 (Cellular repressor of E1A-stimulated genes 1)Creg1 CregO886685
Protein DJ-1Park7A2A8135
Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)Dpy30Q99LT05
Protein FAM162A (E2-induced gene 5 protein homolog) (Growth and transformation-dependent protein) (HGTD-P)Fam162a E2ig5Q9D6U85
Protein FAM177A1Fam177a1Q8BR635
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Prkca PkcaP204445
Protein LSM12 homologLsm12Q9D0R85
Protein misato homolog 1Msto1Q2YDW25
Protein MON2 homolog (Protein SF21)Mon2 Kiaa1040 Sf21Q80TL75
Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1)Pbdc1Q9D0B65
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